(72 nodes) Signal transduction response regulator, receiver domain network (Streptomyces ambofaciens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANB04722.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1333 aa)
	mtrA	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
	ANB04246.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
	ANB04411.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1386 aa)
	yxjL	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	yvfU	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
	yxjL-6	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
	mprA	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
	yxjL-7	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
	mtrA-2	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
	regX	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
	ANB06861.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
	ANB06868.1	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	liaR	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
	regX-2	XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
	ANB07132.1	Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
	mprA-2	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
	yxjL-8	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
	desR	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
	tcrX	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
	ANB07283.1	Nickel transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (1497 aa)
	ANB07444.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
	resD	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
	ANB07556.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
	yxjL-9	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
	yxjL-10	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	yxjL-11	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	cseB	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
	ANB07733.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
	mprA-3	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
	ANB07944.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
	ANB07994.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
	ANB08069.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
	ANB08094.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
	afsQ-4	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
	ANB08289.1	Septum formation initiator; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
	cseB-2	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
	ANB08573.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
	yxjL-12	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
	pcoR	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
	ANB08649.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
	ANB08900.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1793 aa)
	ANB08901.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
	regX-3	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
	ANB08936.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
	ANB08977.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
	cutR	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
	kdpE	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
	ANB09108.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
	ANB09189.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
	tcrX-2	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
	ANB09328.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
	lipReg	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
	yxjL-13	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
	ANB10179.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
	mprA-4	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
	ANB10377.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
	ANB10632.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
	ANB04751.1	Fused response regulator/thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (558 aa)
	afsQ-2	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
	yxjL-2	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
	ANB05026.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
	ANB05099.1	LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
	yxjL-3	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
	yxjL-4	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
	narL	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
	pdtaR	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
	ANB05978.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
	ykoG	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
	ANB06010.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
	yxjL-5	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
	ANB06066.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)

Your Current Organism:

Streptomyces ambofaciens

NCBI taxonomy Id: 1889
Other names: ATCC 23877, BCRC 11857, CBS 616.68, CCRC 11857, CCRC:11857, CECT 3101, DSM 40053, IFO 12836, ISP 5053, JCM 4204, JCM 4618, KCTC 9111, NBRC 12836, NRRL 2420, NRRL B-2516, NRRL-ISP 5053, S. ambofaciens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANB04246.1	ANB06868.1	SAM40697_0283	SAM40697_2910	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.765
ANB04246.1	ANB08900.1	SAM40697_0283	SAM40697_4943	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.845
ANB04246.1	ANB09189.1	SAM40697_0283	SAM40697_5233	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.662
ANB04411.1	ANB04722.1	SAM40697_0449	SAM40697_0761	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.593
ANB04411.1	ANB04751.1	SAM40697_0449	SAM40697_0790	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fused response regulator/thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
ANB04411.1	ANB05099.1	SAM40697_0449	SAM40697_1139	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.414
ANB04411.1	ANB06010.1	SAM40697_0449	SAM40697_2050	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.593
ANB04411.1	ANB07132.1	SAM40697_0449	SAM40697_3174	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.480
ANB04411.1	ANB07283.1	SAM40697_0449	SAM40697_3325	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nickel transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.983
ANB04411.1	ANB08289.1	SAM40697_0449	SAM40697_4331	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Septum formation initiator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.468
ANB04411.1	ANB08573.1	SAM40697_0449	SAM40697_4615	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.612
ANB04411.1	ANB08900.1	SAM40697_0449	SAM40697_4943	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
ANB04411.1	ANB08901.1	SAM40697_0449	SAM40697_4944	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.732
ANB04411.1	ANB10179.1	SAM40697_0449	SAM40697_6226	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.593
ANB04411.1	ANB10632.1	SAM40697_0449	SAM40697_6679	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.610
ANB04411.1	afsQ-2	SAM40697_0449	SAM40697_0861	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.610
ANB04411.1	afsQ-4	SAM40697_0449	SAM40697_4251	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.609
ANB04411.1	cseB	SAM40697_0449	SAM40697_3770	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.613
ANB04411.1	cseB-2	SAM40697_0449	SAM40697_4559	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.613
ANB04411.1	cutR	SAM40697_0449	SAM40697_5044	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.614

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