STRINGSTRING
ANB04276.1 ANB04276.1 mutA mutA yliK yliK ANB04883.1 ANB04883.1 ANB06037.1 ANB06037.1 iolA iolA accA accA fadA fadA ANB06998.1 ANB06998.1 accA-2 accA-2 acs acs ANB07840.1 ANB07840.1 ANB08102.1 ANB08102.1 sucC sucC sucD sucD ANB08170.1 ANB08170.1 bccA bccA pccB pccB ANB08621.1 ANB08621.1 ANB08622.1 ANB08622.1 icmA icmA ackA ackA pta pta gabT gabT ANB09249.1 ANB09249.1 ANB09364.1 ANB09364.1 ANB09454.1 ANB09454.1 ANB09690.1 ANB09690.1 ANB09691.1 ANB09691.1 bktB bktB ANB10360.1 ANB10360.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANB04276.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
mutAmethylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa)
yliKmethylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. (725 aa)
ANB04883.14-aminobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
ANB06037.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
iolAMethylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
accAacetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (646 aa)
fadAacetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
ANB06998.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
accA-2acety-l/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (616 aa)
acsAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
ANB07840.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (428 aa)
ANB08102.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (393 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
ANB08170.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (532 aa)
bccAacetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (590 aa)
pccBmethylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (530 aa)
ANB08621.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
ANB08622.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (382 aa)
icmAmethylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (404 aa)
ptaPhosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (697 aa)
gabT4-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
ANB09249.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
ANB09364.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
ANB09454.1Aminotransferase class III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
ANB09690.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
ANB09691.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (732 aa)
bktBacetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (408 aa)
ANB10360.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (532 aa)
Your Current Organism:
Streptomyces ambofaciens
NCBI taxonomy Id: 1889
Other names: ATCC 23877, BCRC 11857, CBS 616.68, CCRC 11857, CCRC:11857, CECT 3101, DSM 40053, IFO 12836, ISP 5053, JCM 4204, JCM 4618, KCTC 9111, NBRC 12836, NRRL 2420, NRRL B-2516, NRRL-ISP 5053, S. ambofaciens
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