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ORV45136.1 ORV45136.1 ORV46922.1 ORV46922.1 aspA aspA AWC02_01630 AWC02_01630 ORV51827.1 ORV51827.1 dapF dapF dapA dapA dapB dapB AWC02_04485 AWC02_04485 gltD gltD aroQ aroQ aroB aroB aroK aroK ORV49911.1 ORV49911.1 ORV49276.1 ORV49276.1 ORV49311.1 ORV49311.1 ORV47563.1 ORV47563.1 dapD dapD ORV47283.1 ORV47283.1 mdh mdh ORV47315.1 ORV47315.1 lysA lysA ORV47176.1 ORV47176.1 ORV47052.1 ORV47052.1 ORV47086.1 ORV47086.1 ORV46530.1 ORV46530.1 ORV46531.1 ORV46531.1 ORV46532.1 ORV46532.1 ORV45803.1 ORV45803.1 ORV45778.1 ORV45778.1 aroA aroA ORV45063.1 ORV45063.1 ORV45102.1 ORV45102.1 asd asd ORV43357.1 ORV43357.1 ORV42743.1 ORV42743.1 ORV42764.1 ORV42764.1 ORV42811.1 ORV42811.1 ORV42857.1 ORV42857.1 ORV41055.1 ORV41055.1 ORV41102.1 ORV41102.1 ORV41107.1 ORV41107.1 ORV41327.1 ORV41327.1 nadA nadA ORV40153.1 ORV40153.1 ORV39686.1 ORV39686.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ORV45136.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (297 aa)
ORV46922.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (465 aa)
aspAClass II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
AWC02_01630Metal transporter; Catalyzes the Claisen rearrangement of chorismate to prephenate. (183 aa)
ORV51827.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (292 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (300 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (245 aa)
AWC02_04485Glutamine synthetase; Incomplete; too short partial abutting assembly gap; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (1534 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
aroQHypothetical protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (154 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (365 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (201 aa)
ORV49911.1Chorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
ORV49276.1N-acyl-L-amino acid amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
ORV49311.1Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
ORV47563.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (314 aa)
ORV47283.1Succinyl-diaminopimelate desuccinylase; Catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
ORV47315.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (475 aa)
ORV47176.1Dipeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
ORV47052.1Dihydrodipicolinate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
ORV47086.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (81 aa)
ORV46530.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (278 aa)
ORV46531.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (129 aa)
ORV46532.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
ORV45803.1Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (449 aa)
ORV45778.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (429 aa)
ORV45063.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
ORV45102.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (421 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (348 aa)
ORV43357.1Dihydrodipicolinate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
ORV42743.1Citrate lyase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (266 aa)
ORV42764.1NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1617 aa)
ORV42811.1Dihydrodipicolinate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
ORV42857.1Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
ORV41055.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
ORV41102.1Dihydrodipicolinate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
ORV41107.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
ORV41327.1Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family. (462 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (350 aa)
ORV40153.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
ORV39686.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
Your Current Organism:
Mycolicibacter engbaekii
NCBI taxonomy Id: 188915
Other names: ATCC 27353, DSM 45694, M. engbaekii, Mycobacterium engbaekii, Mycobacterium engbaekii Tortoli et al. 2013, Mycolicibacter engbaekii (Tortoli et al. 2013) Gupta et al. 2018
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