(19 nodes) Bacterial chemotaxis network (Methanosarcina acetivorans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	cheD2	Chemotaxis protein CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family. (159 aa)
	cheC2	Chemotaxis protein CheC. (208 aa)
	cheR	cheR methyltransferase. (382 aa)
	cheA2	Chemotaxis sensor histidine kinase. (635 aa)
	cheB2	Chemotaxis protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (356 aa)
	cheY2	Chemotaxis response regulator. (131 aa)
	mcp-2	Methyl-accepting chemotaxis protein. (739 aa)
	cheW2	Chemotaxis signal transduction coupling protein. (184 aa)
	MA_1989	Hypothetical protein (multi-domain). (1052 aa)
	MA_2012	Response regulator receiver. (124 aa)
	cheR-2	cheR methyltransferase. (270 aa)
	cheD1	Chemotaxis protein CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family. (220 aa)
	cheC1	Chemotaxis protein CheC. (203 aa)
	cheA1	Chemotaxis sensor histidine kinase. (882 aa)
	cheB1	Chemotaxis protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (349 aa)
	cheY1	Chemotaxis response regulator. (120 aa)
	cheW1	Chemotaxis signal transduction coupling protein. (182 aa)
	mcp-1	Methyl-accepting chemotaxis protein. (667 aa)
	MA_3542	Conserved hypothetical chemotaxis protein. (1060 aa)

Your Current Organism:

Methanosarcina acetivorans

NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MA_1989	cheA1	MA_1989	MA_3066	Hypothetical protein (multi-domain).	Chemotaxis sensor histidine kinase.	0.916
MA_1989	cheA2	MA_1989	MA_0014	Hypothetical protein (multi-domain).	Chemotaxis sensor histidine kinase.	0.916
MA_1989	cheW1	MA_1989	MA_3070	Hypothetical protein (multi-domain).	Chemotaxis signal transduction coupling protein.	0.729
MA_1989	cheW2	MA_1989	MA_0020	Hypothetical protein (multi-domain).	Chemotaxis signal transduction coupling protein.	0.726
MA_1989	mcp-1	MA_1989	MA_3071	Hypothetical protein (multi-domain).	Methyl-accepting chemotaxis protein.	0.920
MA_1989	mcp-2	MA_1989	MA_0019	Hypothetical protein (multi-domain).	Methyl-accepting chemotaxis protein.	0.918
MA_2012	cheA1	MA_2012	MA_3066	Response regulator receiver.	Chemotaxis sensor histidine kinase.	0.903
MA_2012	cheA2	MA_2012	MA_0014	Response regulator receiver.	Chemotaxis sensor histidine kinase.	0.903
MA_2012	cheB1	MA_2012	MA_3067	Response regulator receiver.	Chemotaxis protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.	0.406
MA_2012	cheC1	MA_2012	MA_3065	Response regulator receiver.	Chemotaxis protein CheC.	0.915
MA_2012	cheC2	MA_2012	MA_0012	Response regulator receiver.	Chemotaxis protein CheC.	0.915
MA_2012	cheW1	MA_2012	MA_3070	Response regulator receiver.	Chemotaxis signal transduction coupling protein.	0.929
MA_2012	cheW2	MA_2012	MA_0020	Response regulator receiver.	Chemotaxis signal transduction coupling protein.	0.929
MA_2012	cheY1	MA_2012	MA_3068	Response regulator receiver.	Chemotaxis response regulator.	0.974
MA_2012	cheY2	MA_2012	MA_0016	Response regulator receiver.	Chemotaxis response regulator.	0.968
MA_2012	mcp-1	MA_2012	MA_3071	Response regulator receiver.	Methyl-accepting chemotaxis protein.	0.950
MA_2012	mcp-2	MA_2012	MA_0019	Response regulator receiver.	Methyl-accepting chemotaxis protein.	0.901
MA_3542	cheA1	MA_3542	MA_3066	Conserved hypothetical chemotaxis protein.	Chemotaxis sensor histidine kinase.	0.916
MA_3542	cheA2	MA_3542	MA_0014	Conserved hypothetical chemotaxis protein.	Chemotaxis sensor histidine kinase.	0.915
MA_3542	cheW1	MA_3542	MA_3070	Conserved hypothetical chemotaxis protein.	Chemotaxis signal transduction coupling protein.	0.728