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eif2a eif2a rpl44e rpl44e srp54 srp54 rpl37e rpl37e rpl21e rpl21e rps3ae rps3ae rpl15e rpl15e rpl37ae rpl37ae rpl3 rpl3 rpl4 rpl4 rpl23 rpl23 rpl2 rpl2 rps19p rps19p rpl22 rpl22 rps3 rps3 rpl29 rpl29 rps17 rps17 rpl14 rpl14 rpl24 rpl24 rps4e rps4e rpl5 rpl5 rps14P rps14P rps8 rps8 rpl32e rpl32e rpl19e rpl19e rpl18 rpl18 rps5 rps5 rpl30 rpl30 rpl34e rpl34e AOL15885.1 AOL15885.1 proS proS AOL15957.1 AOL15957.1 rps24e rps24e AOL15975.1 AOL15975.1 eif2g eif2g rps15 rps15 rpl14e rpl14e AOL16003.1 AOL16003.1 rps19e rps19e rpl39e rpl39e AOL16036.1 AOL16036.1 rpl18a rpl18a rpl11 rpl11 rpl1 rpl1 rpl10 rpl10 rpl12 rpl12 rpl10e rpl10e rps7 rps7 rps28e rps28e rpl40e rpl40e rps8e rps8e gltX gltX rpl7ae rpl7ae rps13 rps13 rps4 rps4 rps11 rps11 rpl18e rpl18e rpl13 rpl13 AOL16252.1 AOL16252.1 rps2 rps2 eif1a eif1a AOL17823.1 AOL17823.1 AOL17113.1 AOL17113.1 rpl13e rpl13e
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
eif2aTranslation initiation factor IF-2 subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (268 aa)
rpl44e50S ribosomal protein L44e; Binds to the 23S rRNA. (95 aa)
srp54Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (445 aa)
rpl37e50S ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (61 aa)
rpl21e50S ribosomal protein L21e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL21 family. (100 aa)
rps3ae30S ribosomal protein S3ae; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS1 family. (208 aa)
rpl15e50S ribosomal protein L15e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL15 family. (216 aa)
rpl37ae50S ribosomal protein L37ae; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily. (70 aa)
rpl350S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (350 aa)
rpl450S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (267 aa)
rpl2350S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (81 aa)
rpl250S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (238 aa)
rps19p30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (140 aa)
rpl2250S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (157 aa)
rps330S ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (225 aa)
rpl2950S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family. (77 aa)
rps1730S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (114 aa)
rpl1450S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (115 aa)
rpl2450S ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit. (133 aa)
rps4e30S ribosomal protein S4e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS4 family. (239 aa)
rpl550S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (177 aa)
rps14P30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles. (54 aa)
rps830S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (133 aa)
rpl32e50S ribosomal protein L32e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL32 family. (134 aa)
rpl19e50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (151 aa)
rpl1850S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (196 aa)
rps530S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy. (214 aa)
rpl3050S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
rpl34e50S ribosomal protein L34e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL34 family. (88 aa)
AOL15885.130S ribosomal protein S26e; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
proSproline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (488 aa)
AOL15957.1Translation initiation factor Sui1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SUI1 family. (100 aa)
rps24e30S ribosomal protein S24e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS24 family. (120 aa)
AOL15975.130S ribosomal protein S25e; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
eif2gTranslation initiation factor IF-2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (413 aa)
rps1530S ribosomal protein S15; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
rpl14e50S ribosomal protein L14e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL14 family. (96 aa)
AOL16003.1Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
rps19e30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (154 aa)
rpl39e50S ribosomal protein L39e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa)
AOL16036.150S ribosomal protein L31e; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)
rpl18a50S ribosomal protein L18a; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
rpl1150S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (170 aa)
rpl150S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (218 aa)
rpl1050S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (335 aa)
rpl1250S ribosomal protein P1; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (106 aa)
rpl10e50S ribosomal protein L16; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL16 family. (175 aa)
rps730S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (193 aa)
rps28e30S ribosomal protein S28e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS28 family. (83 aa)
rpl40e50S ribosomal protein L40e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family. (56 aa)
rps8e30S ribosomal protein S8e; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
gltXglutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (566 aa)
rpl7ae50S ribosomal protein L7ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (128 aa)
rps1330S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (161 aa)
rps430S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa)
rps1130S ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (132 aa)
rpl18e50S ribosomal protein L18e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL18 family. (119 aa)
rpl1350S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (152 aa)
AOL16252.130S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (137 aa)
rps230S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family. (216 aa)
eif1aTranslation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (108 aa)
AOL17823.1Translation initiation factor IF-2 subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
AOL17113.1Elongation factor 1-alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
rpl13e50S ribosomal protein L13e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL13 family. (86 aa)
Your Current Organism:
Sulfolobus sp. A20
NCBI taxonomy Id: 1891280
Other names: S. sp. A20
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