STRINGSTRING
AF331_19640 AF331_19640 murA murA murA-2 murA-2 AF331_19215 AF331_19215 AF331_09690 AF331_09690 ddl ddl murF murF AF331_14340 AF331_14340 AF331_09070 AF331_09070 AF331_15720 AF331_15720 murB murB AF331_16405 AF331_16405 AF331_17535 AF331_17535 murE murE AF331_07205 AF331_07205 AF331_06995 AF331_06995 murE-2 murE-2 mraY mraY murD murD AF331_06970 AF331_06970 divIB divIB ftsA ftsA ftsZ ftsZ AF331_06915 AF331_06915 AF331_06910 AF331_06910 sepF sepF AF331_06900 AF331_06900 AF331_06895 AF331_06895 AF331_06890 AF331_06890 AF331_06170 AF331_06170 AF331_05160 AF331_05160 AF331_04880 AF331_04880 AF331_04265 AF331_04265 murG murG AF331_03800 AF331_03800 gpsB gpsB AF331_03435 AF331_03435 AF331_02170 AF331_02170 AF331_01695 AF331_01695 ezrA ezrA AF331_00595 AF331_00595 AF331_00545 AF331_00545 murC murC AF331_21515 AF331_21515
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AF331_19640Unannotated protein. (689 aa)
murAUnannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (428 aa)
murA-2Unannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (434 aa)
AF331_19215Unannotated protein. (336 aa)
AF331_09690Unannotated protein; Belongs to the SEDS family. (390 aa)
ddlUnannotated protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (354 aa)
murFUnannotated protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (457 aa)
AF331_14340Unannotated protein. (334 aa)
AF331_09070Unannotated protein; Belongs to the peptidase S11 family. (448 aa)
AF331_15720Unannotated protein. (698 aa)
murBUnannotated protein; Cell wall formation. (306 aa)
AF331_16405Unannotated protein. (390 aa)
AF331_17535Unannotated protein. (617 aa)
murEUnannotated protein; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (491 aa)
AF331_07205Unannotated protein; Belongs to the SEDS family. (403 aa)
AF331_06995Unannotated protein. (638 aa)
murE-2Unannotated protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (486 aa)
mraYUnannotated protein; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (324 aa)
murDUnannotated protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (450 aa)
AF331_06970Unannotated protein; Belongs to the SEDS family. (366 aa)
divIBUnannotated protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. (261 aa)
ftsAUnannotated protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (432 aa)
ftsZUnannotated protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (385 aa)
AF331_06915Unannotated protein; Belongs to the multicopper oxidase YfiH/RL5 family. (271 aa)
AF331_06910Unannotated protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (224 aa)
sepFUnannotated protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (148 aa)
AF331_06900Unannotated protein. (87 aa)
AF331_06895Unannotated protein. (256 aa)
AF331_06890Unannotated protein. (171 aa)
AF331_06170Unannotated protein. (302 aa)
AF331_05160Unannotated protein. (716 aa)
AF331_04880Unannotated protein. (711 aa)
AF331_04265Unannotated protein; Belongs to the peptidase S11 family. (393 aa)
murGUnannotated protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (356 aa)
AF331_03800Unannotated protein. (279 aa)
gpsBUnannotated protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. (104 aa)
AF331_03435Unannotated protein. (904 aa)
AF331_02170Unannotated protein. (727 aa)
AF331_01695Unannotated protein. (582 aa)
ezrAUnannotated protein; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (562 aa)
AF331_00595Unannotated protein. (978 aa)
AF331_00545Unannotated protein. (716 aa)
murCUnannotated protein; Cell wall formation; Belongs to the MurCDEF family. (437 aa)
AF331_21515Unannotated protein. (125 aa)
Your Current Organism:
Bacillus marisflavi
NCBI taxonomy Id: 189381
Other names: B. marisflavi, Bacillus marisflavi Yoon et al. 2003, Bacillus sp. JP44SK15, Bacillus sp. JP44SK40, Bacillus sp. LK16, Bacillus sp. LK19, Bacillus sp. LK26, JCM 11544, KCCM 41588, strain TF-11
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