STRINGSTRING
AF331_00370 AF331_00370 murA-2 murA-2 AF331_19995 AF331_19995 noc noc AF331_21515 AF331_21515 spoVG spoVG murC murC AF331_00545 AF331_00545 ezrA ezrA AF331_01020 AF331_01020 GCA_900166615_04173 GCA_900166615_04173 tig tig engB engB AF331_01325 AF331_01325 minC minC AF331_01375 AF331_01375 AF331_01695 AF331_01695 AF331_02310 AF331_02310 xerD xerD scpA scpA scpB scpB gpsB gpsB murG murG spoVS spoVS AF331_06230 AF331_06230 xerC xerC AF331_06890 AF331_06890 AF331_06900 AF331_06900 sepF sepF ftsZ ftsZ ftsA ftsA AF331_06955 AF331_06955 AF331_06960 AF331_06960 divIB divIB AF331_06970 AF331_06970 murD murD mraY mraY murE-2 murE-2 ftsL ftsL AF331_07205 AF331_07205 murE murE GCA_900166615_02697 GCA_900166615_02697 GCA_900166615_02348 GCA_900166615_02348 GCA_900166615_02128 GCA_900166615_02128 whiA whiA AF331_16000 AF331_16000 AF331_15915 AF331_15915 ftsE ftsE murB murB AF331_15370 AF331_15370 AF331_10075 AF331_10075 murF murF murA murA AF331_09690 AF331_09690
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AF331_00370Unannotated protein. (539 aa)
murA-2Unannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (434 aa)
AF331_19995Unannotated protein. (1481 aa)
nocUnannotated protein; Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage. Belongs to the ParB family. (287 aa)
AF331_21515Unannotated protein. (125 aa)
spoVGUnannotated protein; Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation. (97 aa)
murCUnannotated protein; Cell wall formation; Belongs to the MurCDEF family. (437 aa)
AF331_00545Unannotated protein. (716 aa)
ezrAUnannotated protein; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (562 aa)
AF331_01020Unannotated protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (86 aa)
GCA_900166615_04173Unannotated protein. (329 aa)
tigUnannotated protein; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (428 aa)
engBUnannotated protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (194 aa)
AF331_01325Unannotated protein. (311 aa)
minCUnannotated protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (240 aa)
AF331_01375Unannotated protein. (267 aa)
AF331_01695Unannotated protein. (582 aa)
AF331_02310Unannotated protein. (98 aa)
xerDUnannotated protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (298 aa)
scpAUnannotated protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. (260 aa)
scpBUnannotated protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (194 aa)
gpsBUnannotated protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. (104 aa)
murGUnannotated protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (356 aa)
spoVSUnannotated protein. (86 aa)
AF331_06230Unannotated protein; Belongs to the FtsK/SpoIIIE/SftA family. (781 aa)
xerCUnannotated protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (297 aa)
AF331_06890Unannotated protein. (171 aa)
AF331_06900Unannotated protein. (87 aa)
sepFUnannotated protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (148 aa)
ftsZUnannotated protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (385 aa)
ftsAUnannotated protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (432 aa)
AF331_06955Unannotated protein. (236 aa)
AF331_06960Unannotated protein. (236 aa)
divIBUnannotated protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. (261 aa)
AF331_06970Unannotated protein; Belongs to the SEDS family. (366 aa)
murDUnannotated protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (450 aa)
mraYUnannotated protein; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (324 aa)
murE-2Unannotated protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (486 aa)
ftsLUnannotated protein; Essential cell division protein; Belongs to the FtsL family. (119 aa)
AF331_07205Unannotated protein; Belongs to the SEDS family. (403 aa)
murEUnannotated protein; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (491 aa)
GCA_900166615_02697Unannotated protein. (305 aa)
GCA_900166615_02348Unannotated protein. (106 aa)
GCA_900166615_02128Unannotated protein. (70 aa)
whiAUnannotated protein; Involved in cell division and chromosome segregation. (315 aa)
AF331_16000Unannotated protein. (395 aa)
AF331_15915Unannotated protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (294 aa)
ftsEUnannotated protein; Part of the ABC transporter FtsEX involved in cellular division. (228 aa)
murBUnannotated protein; Cell wall formation. (306 aa)
AF331_15370Unannotated protein; Belongs to the 'phage' integrase family. (279 aa)
AF331_10075Unannotated protein. (301 aa)
murFUnannotated protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (457 aa)
murAUnannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (428 aa)
AF331_09690Unannotated protein; Belongs to the SEDS family. (390 aa)
Your Current Organism:
Bacillus marisflavi
NCBI taxonomy Id: 189381
Other names: B. marisflavi, Bacillus marisflavi Yoon et al. 2003, Bacillus sp. JP44SK15, Bacillus sp. JP44SK40, Bacillus sp. LK16, Bacillus sp. LK19, Bacillus sp. LK26, JCM 11544, KCCM 41588, strain TF-11
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