STRINGSTRING
AIQ66384.1 AIQ66384.1 AIQ66458.1 AIQ66458.1 zwf zwf AIQ66991.1 AIQ66991.1 AIQ67171.1 AIQ67171.1 AIQ67196.1 AIQ67196.1 AIQ67428.1 AIQ67428.1 ilvC ilvC ldh ldh leuB leuB AIQ67600.1 AIQ67600.1 AIQ70078.1 AIQ70078.1 AIQ70016.1 AIQ70016.1 dxr dxr AIQ69304.1 AIQ69304.1 AIQ69291.1 AIQ69291.1 ldh-2 ldh-2 murB murB AIQ69068.1 AIQ69068.1 AIQ68995.1 AIQ68995.1 AIQ68485.1 AIQ68485.1 AIQ68465.1 AIQ68465.1 AIQ68381.1 AIQ68381.1 gldA-2 gldA-2 AIQ68317.1 AIQ68317.1 AIQ67849.1 AIQ67849.1 AIQ67959.1 AIQ67959.1 AIQ68058.1 AIQ68058.1 AIQ69870.1 AIQ69870.1 AIQ69843.1 AIQ69843.1 gpsA gpsA AIQ69798.1 AIQ69798.1 AIQ69614.1 AIQ69614.1 AIQ69767.1 AIQ69767.1 mtlD mtlD aroE aroE mdh mdh AIQ68114.1 AIQ68114.1 gldA gldA guaB guaB AIQ66292.1 AIQ66292.1 AIQ66342.1 AIQ66342.1 hisD hisD AIQ70691.1 AIQ70691.1 AIQ70676.1 AIQ70676.1 AIQ70636.1 AIQ70636.1 AIQ70462.1 AIQ70462.1 lutA lutA AIQ70163.1 AIQ70163.1 AIQ70133.1 AIQ70133.1 AIQ70799.1 AIQ70799.1 zwf-2 zwf-2 AIQ71276.1 AIQ71276.1 AIQ71591.1 AIQ71591.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIQ66384.1Acetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (875 aa)
AIQ66458.1Diacetylchitobiose-6-phosphate hydrolase; Catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (503 aa)
AIQ66991.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (471 aa)
AIQ67171.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
AIQ67196.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
AIQ67428.1Glycerol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (330 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (320 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (360 aa)
AIQ67600.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
AIQ70078.1Altronate oxidoreductase; Catalyzes the formation of D-tagaturonate from D-altronate; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
AIQ70016.1Acetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (873 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (379 aa)
AIQ69304.16-phosphogluconate dehydrogenase; Similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
AIQ69291.11,2-propanediol oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
ldh-2Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (308 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (303 aa)
AIQ69068.1Alpha-galactosidase; Catalyses the hydrolysis of terminal non-reducing alpha-D-galactose residues in alpha-D-galactosides; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
AIQ68995.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
AIQ68485.1Acetoin utilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
AIQ68465.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa)
AIQ68381.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
gldA-2Glycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
AIQ68317.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
AIQ67849.1Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
AIQ67959.1Alpha-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
AIQ68058.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
AIQ69870.15-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (366 aa)
AIQ69843.1D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (346 aa)
AIQ69798.12-dehydropantoate 2-reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
AIQ69614.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
AIQ69767.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
mtlDMannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (277 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (313 aa)
AIQ68114.1Diacetylchitobiose-6-phosphate hydrolase; Catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
gldAGlycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa)
AIQ66292.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (315 aa)
AIQ66342.16-phosphogluconate dehydrogenase; Similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa)
AIQ70691.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
AIQ70676.1Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
AIQ70636.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
AIQ70462.1Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (325 aa)
lutAFe-S oxidoreductase; Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. (248 aa)
AIQ70163.1Riboflavin biosynthesis protein RibD; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
AIQ70133.1Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (536 aa)
AIQ70799.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (279 aa)
zwf-2Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (516 aa)
AIQ71276.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (286 aa)
AIQ71591.1FAD-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (663 aa)
Your Current Organism:
Paenibacillus graminis
NCBI taxonomy Id: 189425
Other names: ATCC BAA-95, DSM 15220, LMG 19080, LMG:19080, P. graminis, Paenibacillus graminis Berge et al. 2002, Paenibacillus sp. RSA19, strain RSA19
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