STRINGSTRING
AIQ66660.1 AIQ66660.1 AIQ66813.1 AIQ66813.1 AIQ67217.1 AIQ67217.1 AIQ67495.1 AIQ67495.1 AIQ67496.1 AIQ67496.1 ilvC ilvC leuA leuA leuB leuB ilvD ilvD AIQ67929.1 AIQ67929.1 AIQ68057.1 AIQ68057.1 AIQ68058.1 AIQ68058.1 AIQ68143.1 AIQ68143.1 AIQ68261.1 AIQ68261.1 AIQ68605.1 AIQ68605.1 AIQ68636.1 AIQ68636.1 AIQ69026.1 AIQ69026.1 AIQ69370.1 AIQ69370.1 leuD leuD leuC leuC AIQ69846.1 AIQ69846.1 AIQ69991.1 AIQ69991.1 AIQ70486.1 AIQ70486.1 AIQ70511.1 AIQ70511.1 AIQ70549.1 AIQ70549.1 ilvE ilvE argD argD argB argB argJ argJ argC argC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIQ66660.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
AIQ66813.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (914 aa)
AIQ67217.12-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). Belongs to the alpha-IPM synthase/homocitrate synthase family. (518 aa)
AIQ67495.1Acetolactate synthase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa)
AIQ67496.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (330 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (513 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (360 aa)
ilvDDihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (561 aa)
AIQ67929.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
AIQ68057.1Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
AIQ68058.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
AIQ68143.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
AIQ68261.1Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (539 aa)
AIQ68605.1Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of aspartate semialdehyde from aspartyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family. (347 aa)
AIQ68636.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (367 aa)
AIQ69026.1Acetolactate synthase catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
AIQ69370.1Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (406 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa)
AIQ69846.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (544 aa)
AIQ69991.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (417 aa)
AIQ70486.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
AIQ70511.1Catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (562 aa)
AIQ70549.1Acetyltransferase; Catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. (151 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (293 aa)
argDAcetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (417 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (269 aa)
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (410 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (351 aa)
Your Current Organism:
Paenibacillus graminis
NCBI taxonomy Id: 189425
Other names: ATCC BAA-95, DSM 15220, LMG 19080, LMG:19080, P. graminis, Paenibacillus graminis Berge et al. 2002, Paenibacillus sp. RSA19, strain RSA19
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