STRINGSTRING
spsE-3 spsE-3 dltB-10 dltB-10 LB_285 LB_285 dltB-9 dltB-9 dltB-8 dltB-8 LB_207 LB_207 LB_181 LB_181 LB_170 LB_170 acpP acpP LB_080 LB_080 LB_030 LB_030 lpxD-3 lpxD-3 LA_4215 LA_4215 lpxA lpxA wecE-7 wecE-7 pgi pgi glmU glmU LA_3802 LA_3802 LA_3697 LA_3697 lpxK lpxK wecE-6 wecE-6 kdsB-2 kdsB-2 mdoC mdoC LA_3338 LA_3338 ara1 ara1 LA_3168 LA_3168 LA_3166 LA_3166 LA_2953 LA_2953 LA_2823 LA_2823 dltB-7 dltB-7 rfaF rfaF LA_2580 LA_2580 LA_2546 LA_2546 wcaJ-3 wcaJ-3 kdsA kdsA lpxC lpxC dltB-4 dltB-4 fbp fbp LA_2173 LA_2173 LA_1984 LA_1984 LA_1978 LA_1978 LA_1949 LA_1949 pgk pgk tpiA tpiA LA_1666 LA_1666 LA_1664 LA_1664 LA_1663 LA_1663 rfbA rfbA LA_1658 LA_1658 wecE-5 wecE-5 LA_1650 LA_1650 LA_1649 LA_1649 wcaJ-2 wcaJ-2 LA_1643 LA_1643 kdsB kdsB wecE-4 wecE-4 spsE-2 spsE-2 spsE spsE wecE-3 wecE-3 wecE-2 wecE-2 manC manC kdtA kdtA ugd ugd LA_1382 LA_1382 dltB-2 dltB-2 LA_1307 LA_1307 LA_1280 LA_1280 LA_1276 LA_1276 dltB dltB LA_1097 LA_1097 lpxB lpxB LA_0843 LA_0843 wecE wecE lpxD lpxD LA_0450 LA_0450 LA_0399 LA_0399 LA_0396 LA_0396 wcaJ wcaJ LA_0328 LA_0328 pckA pckA LA_0137 LA_0137
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
spsE-3N-acetylneuraminic (sialic) acid synthetase. (332 aa)
dltB-10Predicted membrane protein involved in D-alaninealginate export/acetyltransferase of MBOAT family; Belongs to the membrane-bound acyltransferase family. (487 aa)
LB_285Hypothetical protein. (264 aa)
dltB-9Predicted membrane protein involved in D-alaninealginate export/acetyltransferase of MBOAT family; Belongs to the membrane-bound acyltransferase family. (465 aa)
dltB-8Predicted membrane protein involved in D-alaninealginate export/acetyltransferase of MBOAT family; Belongs to the membrane-bound acyltransferase family. (470 aa)
LB_207Hypothetical protein. (461 aa)
LB_181Hypothetical protein. (410 aa)
LB_170Nucleoside-diphosphate sugar epimerase. (629 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (77 aa)
LB_080Hypothetical protein. (608 aa)
LB_030Intercellular adhesion protein C. (387 aa)
lpxD-3UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. (371 aa)
LA_4215Strictosidine synthase. (358 aa)
lpxAUDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (259 aa)
wecE-7Pyridoxal phosphate-dependent aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (402 aa)
pgiGlucose-6-phosphate isomerase. (445 aa)
glmUUDP-N-acetylglucosamine diphosphorylase. (252 aa)
LA_3802Glucose-1-phosphate thymidylyltransferase. (348 aa)
LA_3697Hypothetical protein. (674 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (347 aa)
wecE-6Pyridoxal phosphate-dependent aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (374 aa)
kdsB-23-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (247 aa)
mdoCGlucans biosynthesis protein. (358 aa)
LA_3338Putative lipoprotein. (125 aa)
ara1Aldo/keto reductase. (278 aa)
LA_3168Cytoplasmic membrane protein. (67 aa)
LA_3166Metallophosphoesterase. (280 aa)
LA_2953Polysaccharide biosynthesis protein. (428 aa)
LA_2823Putative lipoprotein. (349 aa)
dltB-7Predicted membrane protein involved in D-alaninealginate export/acetyltransferase of MBOAT family; Belongs to the membrane-bound acyltransferase family. (474 aa)
rfaFLipopolysaccharide heptosyltransferase II. (343 aa)
LA_2580Phosphoglycerol transferase-related protein. (651 aa)
LA_2546Capsule biosynthesis protein. (153 aa)
wcaJ-3Glycosyl transferase. (471 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (287 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (337 aa)
dltB-4Predicted membrane protein involved in D-alaninealginate export/acetyltransferase of MBOAT family; Belongs to the membrane-bound acyltransferase family. (494 aa)
fbpFructose-1,6-bisphosphatase. (374 aa)
LA_2173Lipopolysaccharide core biosynthesis protein. (353 aa)
LA_1984Hypothetical protein. (583 aa)
LA_1978Hypothetical protein. (493 aa)
LA_1949Hypothetical protein. (370 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (396 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
LA_1666Glycosyl transferase. (282 aa)
LA_1664dTDP-rhamnosyl transferase. (303 aa)
LA_1663Glycosyl transferase. (301 aa)
rfbAGlucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (294 aa)
LA_1658Glycosyltransferase. (582 aa)
wecE-5Pyridoxal phosphate-dependent aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (363 aa)
LA_1650Glycosyltransferase. (313 aa)
LA_1649Membrane protein involved in the export of O-antigen and teichoic acid. (447 aa)
wcaJ-2Glycosyl transferase. (421 aa)
LA_1643FnlA. (344 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family. (251 aa)
wecE-4Pyridoxal phosphate-dependent aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (394 aa)
spsE-2N-acetylneuraminic (sialic) acid synthetase. (753 aa)
spsEN-acetylneuraminic (sialic) acid synthetase. (344 aa)
wecE-3Pyridoxal phosphate-dependent aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (387 aa)
wecE-2Pyridoxal phosphate-dependent aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (358 aa)
manCMannose-1-phosphate guanylyltransferase. (353 aa)
kdtA3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (418 aa)
ugdUDP-glucose 6-dehydrogenase. (436 aa)
LA_1382Acetyltransferase. (403 aa)
dltB-2Predicted membrane protein involved in D-alaninealginate export/acetyltransferase of MBOAT family; Belongs to the membrane-bound acyltransferase family. (510 aa)
LA_1307Hypothetical protein. (609 aa)
LA_1280Phosphoglycerol transferase-related protein. (662 aa)
LA_1276Sulfatase. (637 aa)
dltBPredicted membrane protein involved in D-alaninealginate export/acetyltransferase of MBOAT family; Belongs to the membrane-bound acyltransferase family. (484 aa)
LA_1097Conserved hypothetical protein. (282 aa)
lpxBLipid-a-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (398 aa)
LA_0843Dolichyl-phosphate-mannose-protein mannosyltransferase. (578 aa)
wecEPyridoxal phosphate-dependent aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (369 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (340 aa)
LA_0450Predicted phosphohydrolase. (272 aa)
LA_0399Paraoxonase. (353 aa)
LA_0396ArnT-like protein. (498 aa)
wcaJGlycosyl transferase. (462 aa)
LA_0328Acetyltransferase. (408 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (530 aa)
LA_0137Hypothetical lipoprotein. (537 aa)
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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