6 items (Mycobacterium sp. KMS) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Mkms_0833	KEGG: mmc:Mmcs_0817 DNA-cytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase. (385 aa)
	Mkms_1569	PFAM: methylenetetrahydrofolate reductase; KEGG: mmc:Mmcs_1546 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (327 aa)
	Mkms_1924	PFAM: Methionine synthase, vitamin-B12 independent; KEGG: mmc:Mmcs_1878 methionine synthase, vitamin-B12 independent. (336 aa)
	metK	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (402 aa)
	Mkms_3211	Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1264 aa)
	Mkms_5285	KEGG: mmc:Mmcs_5197 hypothetical protein. (297 aa)

Your Current Organism:

Mycobacterium sp. KMS

NCBI taxonomy Id: 189918
Other names: M. sp. KMS

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Mkms_0833	metK	Mkms_0833	Mkms_2420	KEGG: mmc:Mmcs_0817 DNA-cytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase.	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.920
Mkms_1569	Mkms_1924	Mkms_1569	Mkms_1924	PFAM: methylenetetrahydrofolate reductase; KEGG: mmc:Mmcs_1546 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	PFAM: Methionine synthase, vitamin-B12 independent; KEGG: mmc:Mmcs_1878 methionine synthase, vitamin-B12 independent.	0.853
Mkms_1569	Mkms_3211	Mkms_1569	Mkms_3211	PFAM: methylenetetrahydrofolate reductase; KEGG: mmc:Mmcs_1546 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.996
Mkms_1569	metK	Mkms_1569	Mkms_2420	PFAM: methylenetetrahydrofolate reductase; KEGG: mmc:Mmcs_1546 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.705
Mkms_1924	Mkms_1569	Mkms_1924	Mkms_1569	PFAM: Methionine synthase, vitamin-B12 independent; KEGG: mmc:Mmcs_1878 methionine synthase, vitamin-B12 independent.	PFAM: methylenetetrahydrofolate reductase; KEGG: mmc:Mmcs_1546 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.853
Mkms_1924	Mkms_3211	Mkms_1924	Mkms_3211	PFAM: Methionine synthase, vitamin-B12 independent; KEGG: mmc:Mmcs_1878 methionine synthase, vitamin-B12 independent.	Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.839
Mkms_1924	Mkms_5285	Mkms_1924	Mkms_5285	PFAM: Methionine synthase, vitamin-B12 independent; KEGG: mmc:Mmcs_1878 methionine synthase, vitamin-B12 independent.	KEGG: mmc:Mmcs_5197 hypothetical protein.	0.787
Mkms_1924	metK	Mkms_1924	Mkms_2420	PFAM: Methionine synthase, vitamin-B12 independent; KEGG: mmc:Mmcs_1878 methionine synthase, vitamin-B12 independent.	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.877
Mkms_3211	Mkms_1569	Mkms_3211	Mkms_1569	Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	PFAM: methylenetetrahydrofolate reductase; KEGG: mmc:Mmcs_1546 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.996
Mkms_3211	Mkms_1924	Mkms_3211	Mkms_1924	Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	PFAM: Methionine synthase, vitamin-B12 independent; KEGG: mmc:Mmcs_1878 methionine synthase, vitamin-B12 independent.	0.839
Mkms_3211	Mkms_5285	Mkms_3211	Mkms_5285	Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	KEGG: mmc:Mmcs_5197 hypothetical protein.	0.951
Mkms_3211	metK	Mkms_3211	Mkms_2420	Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.966
Mkms_5285	Mkms_1924	Mkms_5285	Mkms_1924	KEGG: mmc:Mmcs_5197 hypothetical protein.	PFAM: Methionine synthase, vitamin-B12 independent; KEGG: mmc:Mmcs_1878 methionine synthase, vitamin-B12 independent.	0.787
Mkms_5285	Mkms_3211	Mkms_5285	Mkms_3211	KEGG: mmc:Mmcs_5197 hypothetical protein.	Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.951
Mkms_5285	metK	Mkms_5285	Mkms_2420	KEGG: mmc:Mmcs_5197 hypothetical protein.	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.673
metK	Mkms_0833	Mkms_2420	Mkms_0833	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	KEGG: mmc:Mmcs_0817 DNA-cytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase.	0.920
metK	Mkms_1569	Mkms_2420	Mkms_1569	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	PFAM: methylenetetrahydrofolate reductase; KEGG: mmc:Mmcs_1546 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.705
metK	Mkms_1924	Mkms_2420	Mkms_1924	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	PFAM: Methionine synthase, vitamin-B12 independent; KEGG: mmc:Mmcs_1878 methionine synthase, vitamin-B12 independent.	0.877
metK	Mkms_3211	Mkms_2420	Mkms_3211	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.966
metK	Mkms_5285	Mkms_2420	Mkms_5285	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	KEGG: mmc:Mmcs_5197 hypothetical protein.	0.673