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Mkms_0090 Mkms_0090 Mkms_0391 Mkms_0391 Mkms_0392 Mkms_0392 Mkms_0514 Mkms_0514 Mkms_0644 Mkms_0644 deoC deoC gpmA gpmA Mkms_1110 Mkms_1110 Mkms_1504 Mkms_1504 Mkms_1711 Mkms_1711 pfkA pfkA Mkms_2067 Mkms_2067 Mkms_2333 Mkms_2333 Mkms_2432 Mkms_2432 Mkms_2450 Mkms_2450 pgk pgk tpiA tpiA xylB xylB Mkms_2599 Mkms_2599 Mkms_2605 Mkms_2605 Mkms_2606 Mkms_2606 Mkms_2748 Mkms_2748 Mkms_2831 Mkms_2831 xylB-2 xylB-2 Mkms_3101 Mkms_3101 Mkms_3140 Mkms_3140 Mkms_3141 Mkms_3141 Mkms_3375 Mkms_3375 Mkms_3424 Mkms_3424 Mkms_3547 Mkms_3547 Mkms_3606 Mkms_3606 rbsK rbsK Mkms_3684 Mkms_3684 Mkms_3697 Mkms_3697 glgE glgE Mkms_3977 Mkms_3977 Mkms_3978 Mkms_3978 eno eno pgi pgi Mkms_4487 Mkms_4487 Mkms_4517 Mkms_4517 Mkms_4643 Mkms_4643 Mkms_4686 Mkms_4686 Mkms_4819 Mkms_4819 Mkms_4859 Mkms_4859 glpK glpK Mkms_5058 Mkms_5058 Mkms_5121 Mkms_5121 Mkms_5204 Mkms_5204 Mkms_5210 Mkms_5210 Mkms_5222 Mkms_5222 Mkms_5230 Mkms_5230 Mkms_5390 Mkms_5390
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mkms_0090PFAM: PfkB domain protein; KEGG: mmc:Mmcs_0081 PfkB; Belongs to the carbohydrate kinase PfkB family. (325 aa)
Mkms_0391PFAM: Lactate/malate dehydrogenase; KEGG: mmc:Mmcs_0382 lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily. (329 aa)
Mkms_0392PFAM: pyruvate kinase; KEGG: mmc:Mmcs_0383 pyruvate kinase. (615 aa)
Mkms_0514Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (345 aa)
Mkms_0644TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: mmc:Mmcs_0631 dihydrolipoamide dehydrogenase. (466 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (226 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
Mkms_1110PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: mmc:Mmcs_1093 catalytic domain of components of various dehydrogenase complexes. (399 aa)
Mkms_1504PFAM: Alcohol dehydrogenase GroES domain protein; KEGG: mmc:Mmcs_1482 alcohol dehydrogenase GroES-like protein. (340 aa)
Mkms_17114,5-dihydroxyphthalate dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; homoserine dehydrogenase, NAD-binding; KEGG: mmc:Mmcs_1682 oxidoreductase-like protein. (409 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (343 aa)
Mkms_2067PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mmc:Mmcs_2021 alcohol dehydrogenase, zinc-binding protein. (321 aa)
Mkms_2333PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mmc:Mmcs_2286 alcohol dehydrogenase GroES-like protein. (385 aa)
Mkms_2432PFAM: ribulose-phosphate 3-epimerase; KEGG: mmc:Mmcs_2385 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (224 aa)
Mkms_2450KEGG: mmc:Mmcs_2404 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (340 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: mmc:Mmcs_2405 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (407 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
xylBTIGRFAM: xylulokinase; PFAM: carbohydrate kinase, FGGY; KEGG: mmc:Mmcs_2519 xylulokinase. (465 aa)
Mkms_2599PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mmc:Mmcs_2554 alcohol dehydrogenase GroES-like protein. (362 aa)
Mkms_2605Homodimeric dihydroxyacetone kinase; PFAM: Dak kinase; Dak phosphatase; KEGG: mmc:Mmcs_2560 glycerone kinase. (581 aa)
Mkms_2606Ribose 5-phosphate isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family; ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; KEGG: mmc:Mmcs_2561 ribose 5-phosphate isomerase. (159 aa)
Mkms_2748PFAM: fructose-bisphosphate aldolase, class-I; KEGG: mmc:Mmcs_2704 fructose-bisphosphate aldolase. (297 aa)
Mkms_2831PFAM: ribulose-phosphate 3-epimerase; KEGG: mmc:Mmcs_2787 ribulose-phosphate 3-epimerase. (216 aa)
xylB-2TIGRFAM: xylulokinase; PFAM: carbohydrate kinase, FGGY; KEGG: mmc:Mmcs_2788 xylulokinase. (493 aa)
Mkms_3101PFAM: pyruvate kinase; KEGG: mmc:Mmcs_3042 pyruvate kinase; Belongs to the pyruvate kinase family. (472 aa)
Mkms_3140Isoamylase; KEGG: mmc:Mmcs_3080 glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; Belongs to the glycosyl hydrolase 13 family. (720 aa)
Mkms_3141KEGG: mmc:Mmcs_3081 malto-oligosyltrehalose synthase; TIGRFAM: malto-oligosyltrehalose synthase; PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain. (774 aa)
Mkms_33752-oxoglutarate dehydrogenase E2 component; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: mmc:Mmcs_3313 catalytic domain of components of various dehydrogenase complexes. (629 aa)
Mkms_34242-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (929 aa)
Mkms_3547PFAM: glycoside hydrolase 15-related; KEGG: mmc:Mmcs_3484 glycoside hydrolase 15-related. (677 aa)
Mkms_3606PFAM: carbohydrate kinase, FGGY; KEGG: mmc:Mmcs_3533 carbohydrate kinase, FGGY; Belongs to the FGGY kinase family. (482 aa)
rbsKPfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (285 aa)
Mkms_3684PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: mmc:Mmcs_3611 alpha amylase, catalytic region. (539 aa)
Mkms_3697PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: mmc:Mmcs_3624 catalytic domain of components of various dehydrogenase complexes. (384 aa)
glgEAlpha amylase, catalytic region; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB; Belongs to the glycosyl hydrolase 13 family. GlgE subfamily. (695 aa)
Mkms_3977PFAM: Alcohol dehydrogenase, zinc-binding domain protein; KEGG: mmc:Mmcs_3903 alcohol dehydrogenase, zinc-binding protein. (364 aa)
Mkms_3978PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; KEGG: mmc:Mmcs_3904 oxidoreductase-like protein. (324 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: mmc:Mmcs_4334 glucose-6-phosphate isomerase; Belongs to the GPI family. (554 aa)
Mkms_4487PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; KEGG: mmc:Mmcs_4400 oxidoreductase-like protein. (317 aa)
Mkms_4517KEGG: mmc:Mmcs_4430 hypothetical protein. (372 aa)
Mkms_4643PFAM: beta-lactamase domain protein; KEGG: mmc:Mmcs_4555 beta-lactamase-like protein. (217 aa)
Mkms_4686PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: mmc:Mmcs_4598 alpha amylase, catalytic region. (559 aa)
Mkms_4819KEGG: mmc:Mmcs_4733 hypothetical protein. (293 aa)
Mkms_4859PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mmc:Mmcs_4773 alcohol dehydrogenase, zinc-binding protein. (338 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (510 aa)
Mkms_5058PFAM: Phosphoglycerate mutase; KEGG: mmc:Mmcs_4970 phosphoglycerate mutase. (203 aa)
Mkms_5121PFAM: Phosphoglycerate mutase; KEGG: mmc:Mmcs_5033 phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (228 aa)
Mkms_5204Isoamylase; KEGG: mmc:Mmcs_5115 glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; Belongs to the glycosyl hydrolase 13 family. (714 aa)
Mkms_5210KEGG: mmc:Mmcs_5121 trehalose synthase-like protein; TIGRFAM: trehalose synthase; PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain. (596 aa)
Mkms_5222KEGG: mmc:Mmcs_5133 dihydroxyacetone kinase, subunit L; TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: Dak kinase; Dak phosphatase. (544 aa)
Mkms_5230PFAM: Phosphoglycerate mutase; KEGG: mmc:Mmcs_5141 phosphoglycerate mutase. (231 aa)
Mkms_5390Cellulase; PFAM: glycoside hydrolase, family 6; KEGG: mmc:Mmcs_5301 cellulase; Belongs to the glycosyl hydrolase family 6. (329 aa)
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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