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rph rph rnhA rnhA Mkms_4330 Mkms_4330 xseB xseB xseA xseA deaD deaD Mkms_3917 Mkms_3917 Mkms_3516 Mkms_3516 Mkms_3506 Mkms_3506 Mkms_3233 Mkms_3233 Mkms_3105 Mkms_3105 Mkms_2521 Mkms_2521 Mkms_2290 Mkms_2290 dut dut Mkms_2211 Mkms_2211 pnp pnp rnhB rnhB Mkms_1795 Mkms_1795 Mkms_1496 Mkms_1496 Mkms_1425 Mkms_1425 Mkms_1408 Mkms_1408 Mkms_1248 Mkms_1248 Mkms_1195 Mkms_1195 Mkms_0929 Mkms_0929 deoC deoC
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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textmining
co-expression
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rphRNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (260 aa)
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (154 aa)
Mkms_4330PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mmc:Mmcs_4244 MazG nucleotide pyrophosphohydrolase. (320 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (70 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (411 aa)
deaDATP-dependent RNA helicase CsdA; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (557 aa)
Mkms_3917Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (196 aa)
Mkms_3516KEGG: mmc:Mmcs_3453 hypothetical protein. (106 aa)
Mkms_3506KEGG: mmc:Mmcs_3443 deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: putative deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; Belongs to the dGTPase family. Type 2 subfamily. (423 aa)
Mkms_3233TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; KEGG: mmc:Mmcs_5596 metal dependent phosphohydrolase. (178 aa)
Mkms_3105PFAM: TM2 domain containing protein+B7201; KEGG: mmc:Mmcs_3046 TM2 domain containing protein. (127 aa)
Mkms_2521PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DSH domain protein; SMART: DEAD-like helicases-like; KEGG: mmc:Mmcs_2476 DEAD/DEAH box helicase-like protein. (918 aa)
Mkms_2290PFAM: histidine triad (HIT) protein; KEGG: mmc:Mmcs_2243 histidine triad (HIT) protein. (244 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (154 aa)
Mkms_2211PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: mmc:Mmcs_2165 DEAD/DEAH box helicase-like protein. (444 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (759 aa)
rnhBRNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (239 aa)
Mkms_1795TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: mmc:Mmcs_1748 diguanylate cyclase/phosphodiesterase with GAF sensor. (601 aa)
Mkms_1496SMART: TIR protein; KEGG: mmc:Mmcs_1472 toll-interleukin receptor. (283 aa)
Mkms_1425PFAM: NUDIX hydrolase; KEGG: mmc:Mmcs_1407 NUDIX hydrolase. (311 aa)
Mkms_1408PFAM: metal-dependent phosphohydrolase, HD sub domain; KEGG: mmc:Mmcs_1390 metal dependent phosphohydrolase. (212 aa)
Mkms_1248TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: mmc:Mmcs_1231 cytidine deaminase, homotetrameric. (138 aa)
Mkms_1195PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: mmc:Mmcs_1178 inosine/uridine-preferring nucleoside hydrolase. (349 aa)
Mkms_0929PFAM: metal-dependent phosphohydrolase, HD sub domain; KEGG: mmc:Mmcs_0912 metal dependent phosphohydrolase. (213 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (226 aa)
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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