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Mkms_1109 Mkms_1109 Mkms_2837 Mkms_2837 Mkms_3424 Mkms_3424 Mkms_3640 Mkms_3640 Mkms_2460 Mkms_2460 Mkms_2022 Mkms_2022 dxs dxs Mkms_4954 Mkms_4954 Mkms_3698 Mkms_3698
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mkms_1109Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa)
Mkms_2837PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: mmc:Mmcs_2793 fructose-6-phosphate phosphoketolase. (806 aa)
Mkms_34242-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (929 aa)
Mkms_3640PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mmc:Mmcs_3567 pyruvate flavodoxin/ferredoxin oxidoreductase-like protein. (643 aa)
Mkms_2460Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (697 aa)
Mkms_2022PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: mmc:Mmcs_1976 transketolase, central region. (721 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa)
Mkms_4954PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mmc:Mmcs_4865 pyruvate:ferredoxin (flavodoxin) oxidoreductase. (1191 aa)
Mkms_3698PFAM: Transketolase, central region; Transketolase domain protein; KEGG: mmc:Mmcs_3625 transketolase, central region. (349 aa)
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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