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Mkms_0243 Mkms_0243 Mkms_0451 Mkms_0451 Mkms_0523 Mkms_0523 purA purA Mkms_0887 Mkms_0887 glmS glmS Mkms_1162 Mkms_1162 Mkms_2101 Mkms_2101 Mkms_2103 Mkms_2103 Mkms_2150 Mkms_2150 Mkms_2321 Mkms_2321 pyrB pyrB carA carA carB carB Mkms_2798 Mkms_2798 argH argH argG argG Mkms_3102 Mkms_3102 Mkms_3103 Mkms_3103 Mkms_3127 Mkms_3127 Mkms_3154 Mkms_3154 Mkms_3361 Mkms_3361 Mkms_3382 Mkms_3382 Mkms_3390 Mkms_3390 Mkms_3414 Mkms_3414 Mkms_3687 Mkms_3687 Mkms_4101 Mkms_4101 Mkms_4353 Mkms_4353 Mkms_4419 Mkms_4419 purF purF purQ purQ Mkms_4654 Mkms_4654 Mkms_4981 Mkms_4981 Mkms_5153 Mkms_5153 Mkms_5154 Mkms_5154 Mkms_5433 Mkms_5433
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mkms_0243PFAM: glutamine synthetase, catalytic region; KEGG: mmc:Mmcs_0233 glutamine synthetase, catalytic region. (437 aa)
Mkms_0451PFAM: aminotransferase, class I and II; KEGG: mmc:Mmcs_0441 aminotransferase, class I and II. (428 aa)
Mkms_0523Glutamate--ammonia ligase; PFAM: glutamine synthetase, catalytic region; KEGG: mmc:Mmcs_0512 glutamate--ammonia ligase. (466 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa)
Mkms_0887Glutamate--ammonia ligase; PFAM: glutamine synthetase, catalytic region; KEGG: mmc:Mmcs_0870 glutamate--ammonia ligase. (453 aa)
glmSGlutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (621 aa)
Mkms_1162KEGG: mmc:Mmcs_1145 glutamate decarboxylase; TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; Belongs to the group II decarboxylase family. (461 aa)
Mkms_2101KEGG: mmc:Mmcs_2055 asparagine synthase, glutamine-hydrolyzing; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase. (601 aa)
Mkms_2103Glutamate--ammonia ligase; PFAM: glutamine synthetase, catalytic region; KEGG: mmc:Mmcs_2057 glutamate--ammonia ligase. (455 aa)
Mkms_2150TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: mmc:Mmcs_2104 alanine dehydrogenase; Belongs to the AlaDH/PNT family. (371 aa)
Mkms_2321TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: mmc:Mmcs_2274 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (446 aa)
pyrBTIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; KEGG: mmc:Mmcs_2363 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (316 aa)
carAKEGG: mmc:Mmcs_2366 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; Belongs to the CarA family. (387 aa)
carBTIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: mmc:Mmcs_2367 carbamoyl-phosphate synthase, large subunit. (1112 aa)
Mkms_2798PFAM: glutamine synthetase, catalytic region; KEGG: mmc:Mmcs_2754 glutamine synthetase, catalytic region. (450 aa)
argHTIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mmc:Mmcs_2965 argininosuccinate lyase. (470 aa)
argGPFAM: argininosuccinate synthase; KEGG: mmc:Mmcs_2966 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (400 aa)
Mkms_3102TIGRFAM: glutamate synthases, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mmc:Mmcs_3043 glutamate synthases, NADH/NADPH, small subunit. (502 aa)
Mkms_3103PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: mmc:Mmcs_3044 glutamate synthase (ferredoxin). (1518 aa)
Mkms_3127L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (548 aa)
Mkms_3154PFAM: Asparaginase/glutaminase; KEGG: mmc:Mmcs_3094 asparaginase/glutaminase. (309 aa)
Mkms_3361KEGG: mmc:Mmcs_3299 asparagine synthase, glutamine-hydrolyzing; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase. (655 aa)
Mkms_3382KEGG: mmc:Mmcs_3320 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp. (478 aa)
Mkms_3390KEGG: mmc:Mmcs_3328 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp. (446 aa)
Mkms_3414Glutamine--fructose-6-phosphate transaminase; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase, isomerizing; PFAM: glutamine amidotransferase, class-II; sugar isomerase (SIS); KEGG: mmc:Mmcs_3352 glucosamine--fructose-6-phosphate aminotransferase, isomerizing. (595 aa)
Mkms_3687PFAM: NAD-glutamate dehydrogenase; KEGG: mmc:Mmcs_3614 NAD-glutamate dehydrogenase. (1619 aa)
Mkms_4101TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_4026 delta-1-pyrroline-5-carboxylate dehydrogenase. (542 aa)
Mkms_4353Glutamate dehydrogenase (NADP); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: mmc:Mmcs_4267 glutamate dehydrogenase (NADP+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (448 aa)
Mkms_4419PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_4333 succinate-semialdehyde dehydrogenase (NAD(P)+); Belongs to the aldehyde dehydrogenase family. (482 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (511 aa)
purQPhosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (224 aa)
Mkms_4654KEGG: mmc:Mmcs_4566 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (475 aa)
Mkms_4981Glutamate--ammonia ligase; PFAM: glutamine synthetase, catalytic region; KEGG: mmc:Mmcs_4892 glutamate--ammonia ligase. (436 aa)
Mkms_5153TIGRFAM: glutamate synthases, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mmc:Mmcs_5065 glutamate synthases, NADH/NADPH, small subunit. (489 aa)
Mkms_5154PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: mmc:Mmcs_5066 glutamate synthase (ferredoxin). (1527 aa)
Mkms_5433PFAM: glutamine synthetase, catalytic region; KEGG: mmc:Mmcs_5344 glutamate--ammonia ligase. (451 aa)
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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