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Mkms_0045 Mkms_0045 Mkms_0391 Mkms_0391 metZ metZ mtnP mtnP Mkms_0833 Mkms_0833 metXA metXA Mkms_1225 Mkms_1225 Mkms_1308 Mkms_1308 ahcY ahcY Mkms_1462 Mkms_1462 speE speE Mkms_1956 Mkms_1956 Mkms_1974 Mkms_1974 metK metK Mkms_2568 Mkms_2568 Mkms_3211 Mkms_3211 Mkms_3370 Mkms_3370 Mkms_3970 Mkms_3970 Mkms_4221 Mkms_4221 Mkms_4224 Mkms_4224 Mkms_4263 Mkms_4263 serC serC Mkms_4616 Mkms_4616 Mkms_4806 Mkms_4806 Mkms_4913 Mkms_4913 egtA egtA asd asd Mkms_4978 Mkms_4978 Mkms_5434 Mkms_5434
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
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Mkms_0045Homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; KEGG: mmc:Mmcs_0036 homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. (342 aa)
Mkms_0391PFAM: Lactate/malate dehydrogenase; KEGG: mmc:Mmcs_0382 lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily. (329 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (412 aa)
mtnPMethylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (258 aa)
Mkms_0833KEGG: mmc:Mmcs_0817 DNA-cytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase. (385 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (373 aa)
Mkms_1225KEGG: mmc:Mmcs_1208 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase. (435 aa)
Mkms_1308PFAM: Rhodanese domain protein; KEGG: mmc:Mmcs_1291 rhodanese-like protein. (298 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (489 aa)
Mkms_1462PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mmc:Mmcs_1444 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (371 aa)
speESpermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (520 aa)
Mkms_1956TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: mmc:Mmcs_1910 D-3-phosphoglycerate dehydrogenase. (528 aa)
Mkms_1974PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: mmc:Mmcs_1928 Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. (367 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (402 aa)
Mkms_2568PFAM: Rhodanese domain protein; KEGG: mmc:Mmcs_2523 rhodanese-like protein. (266 aa)
Mkms_3211Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1264 aa)
Mkms_3370KEGG: mmc:Mmcs_3308 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. (368 aa)
Mkms_3970PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: mmc:Mmcs_3896 homoserine dehydrogenase. (445 aa)
Mkms_4221Cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mmc:Mmcs_4146 cystathionine gamma-synthase. (392 aa)
Mkms_4224KEGG: mmc:Mmcs_4149 cystathionine beta-synthase; TIGRFAM: cystathionine beta-synthase; PFAM: CBS domain containing protein; Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (464 aa)
Mkms_4263PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mmc:Mmcs_4197 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (369 aa)
serCAminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (370 aa)
Mkms_4616Thiosulfate sulfurtransferase; PFAM: Rhodanese domain protein; KEGG: mmc:Mmcs_4529 thiosulfate sulfurtransferase. (277 aa)
Mkms_4806Thiosulfate sulfurtransferase; PFAM: Rhodanese domain protein; KEGG: mmc:Mmcs_4720 thiosulfate sulfurtransferase. (279 aa)
Mkms_4913PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mmc:Mmcs_4827 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (368 aa)
egtAGlutamate--cysteine ligase, GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. (424 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
Mkms_4978KEGG: mmc:Mmcs_4889 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (421 aa)
Mkms_5434KEGG: mmc:Mmcs_5345 homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. (343 aa)
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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