STRINGSTRING
trxA trxA bkdC bkdC ANW19179.1 ANW19179.1 adhA adhA ANW18771.1 ANW18771.1 ANW18769.1 ANW18769.1 ANW18762.1 ANW18762.1 secE secE secY secY ANW18533.1 ANW18533.1 msrA msrA ahpD ahpD ahpC ahpC ANW18332.1 ANW18332.1 ANW18330.1 ANW18330.1 ANW18329.1 ANW18329.1 ANW18328.1 ANW18328.1 oppB oppB ANW18322.1 ANW18322.1 ANW18275.1 ANW18275.1 ANW18274.1 ANW18274.1 ANW18273.1 ANW18273.1 oppA2 oppA2 oppA1 oppA1 ANW18048.1 ANW18048.1 ANW18025.1 ANW18025.1 ANW17991.1 ANW17991.1 ANW17990.1 ANW17990.1 ANW17956.1 ANW17956.1 ANW17955.1 ANW17955.1 ANW17954.1 ANW17954.1 ANW17783.1 ANW17783.1 ANW17782.1 ANW17782.1 ANW17781.1 ANW17781.1 ANW21806.1 ANW21806.1 amfB amfB amfA amfA ANW17403.1 ANW17403.1 ANW17191.1 ANW17191.1 ANW17189.1 ANW17189.1 ANW17186.1 ANW17186.1 ANW17081.1 ANW17081.1 ANW17029.1 ANW17029.1 ycdM ycdM ANW16832.1 ANW16832.1 ANW21739.1 ANW21739.1 ANW21738.1 ANW21738.1 ANW21681.1 ANW21681.1 secF-2 secF-2 ANW21600.1 ANW21600.1 ANW21383.1 ANW21383.1 ANW21382.1 ANW21382.1 ANW21377.1 ANW21377.1 ANW21365.1 ANW21365.1 ANW21349.1 ANW21349.1 ANW21339.1 ANW21339.1 ANW21309.1 ANW21309.1 ANW21308.1 ANW21308.1 ANW21228.1 ANW21228.1 secF secF secD secD ANW21010.1 ANW21010.1 ANW20984.1 ANW20984.1 ANW20964.1 ANW20964.1 ANW20954.1 ANW20954.1 ANW20909.1 ANW20909.1 ANW20908.1 ANW20908.1 secG secG ANW20593.1 ANW20593.1 ANW20551.1 ANW20551.1 ANW20543.1 ANW20543.1 ANW20534.1 ANW20534.1 ANW20533.1 ANW20533.1 ANW20422.1 ANW20422.1 ANW20414.1 ANW20414.1 ANW20367.1 ANW20367.1 ANW20316.1 ANW20316.1 ANW20315.1 ANW20315.1 sodF sodF ANW20170.1 ANW20170.1 ANW20102.1 ANW20102.1 sidE sidE ANW20054.1 ANW20054.1 ANW21999.1 ANW21999.1 bcp bcp secA secA ANW19659.1 ANW19659.1 ANW19439.1 ANW19439.1 ANW19438.1 ANW19438.1 ANW21952.1 ANW21952.1 ANW19424.1 ANW19424.1 ANW19356.1 ANW19356.1 ANW19303.1 ANW19303.1 trxB trxB cvm5 cvm5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
trxAThioredoxin; Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. (110 aa)
bkdCBranched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
ANW19179.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
adhAZn-dependent alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
ANW18771.1LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
ANW18769.1Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
ANW18762.1LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (92 aa)
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (439 aa)
ANW18533.1Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (173 aa)
msrAPeptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (224 aa)
ahpDAlkyl hydroperoxide reductase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. (178 aa)
ahpCAlkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
ANW18332.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (803 aa)
ANW18330.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
ANW18329.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (597 aa)
ANW18328.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
oppBABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
ANW18322.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
ANW18275.1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (568 aa)
ANW18274.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
ANW18273.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
oppA2Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
oppA1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
ANW18048.1Alkane 1-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
ANW18025.1Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
ANW17991.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (643 aa)
ANW17990.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (638 aa)
ANW17956.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
ANW17955.1Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa)
ANW17954.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
ANW17783.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
ANW17782.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
ANW17781.1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (605 aa)
ANW21806.1LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
amfBHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (885 aa)
amfAABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (585 aa)
ANW17403.1LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
ANW17191.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
ANW17189.1Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
ANW17186.1Non-ribosomal peptide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
ANW17081.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
ANW17029.1Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
ycdMPyrimidine utilization protein A; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. (360 aa)
ANW16832.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
ANW21739.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
ANW21738.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
ANW21681.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (633 aa)
secF-2Protein translocase subunit SecDF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (763 aa)
ANW21600.1NADPH-dependent ferric siderophore reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
ANW21383.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa)
ANW21382.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa)
ANW21377.1NADPH-dependent ferric siderophore reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
ANW21365.1Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
ANW21349.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (604 aa)
ANW21339.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
ANW21309.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (625 aa)
ANW21308.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa)
ANW21228.1Peptide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (526 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (373 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (577 aa)
ANW21010.1NADPH-dependent ferric siderophore reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
ANW20984.1Peptide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (528 aa)
ANW20964.1LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
ANW20954.1S-(hydroxymethyl)mycothiol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
ANW20909.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
ANW20908.1FMNH2-dependent monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
secGPreprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (75 aa)
ANW20593.1Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (159 aa)
ANW20551.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa)
ANW20543.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (624 aa)
ANW20534.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
ANW20533.12-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
ANW20422.1Zn-dependent alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
ANW20414.1LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
ANW20367.1Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
ANW20316.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (577 aa)
ANW20315.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (644 aa)
sodFSuperoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (211 aa)
ANW20170.1Globin; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
ANW20102.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (1275 aa)
sidENADPH-dependent ferric siderophore reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
ANW20054.1Alkanal monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
ANW21999.1Preprotein translocase subunit SecA; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
bcpPeroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (935 aa)
ANW19659.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (766 aa)
ANW19439.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
ANW19438.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
ANW21952.1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
ANW19424.1LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
ANW19356.15,10-methylene tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
ANW19303.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (1238 aa)
trxBThioredoxin-disulfide reductase; Component of the thioredoxin-thioredoxin reductase system which may be involved in biosynthesis of penicillins and cephalosporins and may be important in determining the thiol-disulfide redox balance. (322 aa)
cvm5Methylene-tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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