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sdhC sdhC sdhD sdhD sdhA sdhA sdhB sdhB accA accA AQS41302.1 AQS41302.1 gltA gltA AQS41484.1 AQS41484.1 pdhA pdhA AQS41526.1 AQS41526.1 AQS41527.1 AQS41527.1 AQS41528.1 AQS41528.1 AQS41560.1 AQS41560.1 AQS41580.1 AQS41580.1 accC accC accB accB AQS41833.1 AQS41833.1 AQS41855.1 AQS41855.1 AQS42053.1 AQS42053.1 fumC fumC accD accD AQS42386.1 AQS42386.1 AQS42388.1 AQS42388.1 AQS42389.1 AQS42389.1 sucD sucD sucC sucC mdh mdh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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sdhCSuccinate dehydrogenase cytochrome b556 subunit; Bhsal00310. (133 aa)
sdhDSuccinate dehydrogenase hydrophobic membrane anchor protein; Bhsal00320. (128 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Bhsal00330; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (614 aa)
sdhBSuccinate dehydrogenase iron-sulfur subunit; Bhsal00340; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
AQS41302.1Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta region; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (539 aa)
gltACitrate synthase; Bhsal07440; Belongs to the citrate synthase family. (430 aa)
AQS41484.1Glutathione-disulfide reductase; Maintains high levels of reduced glutathione. (463 aa)
pdhAPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (346 aa)
AQS41526.1Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (460 aa)
AQS41527.1Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (442 aa)
AQS41528.1Dihydrolipoyl dehydrogenase; Bhsal08110. (486 aa)
AQS41560.1Isocitrate dehydrogenase [NADP]; Bhsal08430; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa)
AQS41580.1Acetyl/propionyl-CoA carboxylase alpha subunit; Bhsal08630. (577 aa)
accCAcetyl-CoA carboxylase, biotin carboxylase AccC; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa)
accBAcetyl-CoA carboxylase, biotin carboxyl carrier protein AccB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (155 aa)
AQS41833.1Succinate CoA transferase; Bhsal11180. (497 aa)
AQS41855.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (894 aa)
AQS42053.1Methylmalonyl-CoA mutase; Bhsal13410. (440 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (289 aa)
AQS42386.1Dihydrolipoyl dehydrogenase; Bhsal16790. (468 aa)
AQS42388.1Hypothetical protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (406 aa)
AQS42389.12-oxoglutarate dehydrogenase E1 component; Bhsal16820. (996 aa)
sucDSuccinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
sucCSuccinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (398 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
Your Current Organism:
Tokpelaia hoelldoblerii
NCBI taxonomy Id: 1902579
Other names: C. Tokpelaia hoelldoblerii, Candidatus Tokpelaia hoelldoblerii
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