(6 nodes) Pyrimidine nucleoside triphosphate metabolic process network (Betaproteobacteria bacterium GR1643)

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Your Input:
	dut	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (149 aa)
	pyrG	CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (556 aa)
	ndk	Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
	tmk	dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (206 aa)
	tdk	Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
	dcd	dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. (188 aa)

Your Current Organism:

Betaproteobacteria bacterium GR1643

NCBI taxonomy Id: 1904640
Other names: B. bacterium GR16-43, Betaproteobacteria bacterium GR16-43, Nnibrrimonas geomnyongensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dcd	dut	BWI17_19970	BWI17_00405	dCTP deaminase; Catalyzes the deamination of dCTP to dUTP.	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	0.964
dcd	ndk	BWI17_19970	BWI17_12695	dCTP deaminase; Catalyzes the deamination of dCTP to dUTP.	Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.964
dcd	pyrG	BWI17_19970	BWI17_10250	dCTP deaminase; Catalyzes the deamination of dCTP to dUTP.	CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.925
dcd	tdk	BWI17_19970	BWI17_16220	dCTP deaminase; Catalyzes the deamination of dCTP to dUTP.	Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.544
dcd	tmk	BWI17_19970	BWI17_15910	dCTP deaminase; Catalyzes the deamination of dCTP to dUTP.	dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.473
dut	dcd	BWI17_00405	BWI17_19970	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	dCTP deaminase; Catalyzes the deamination of dCTP to dUTP.	0.964
dut	ndk	BWI17_00405	BWI17_12695	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.971
dut	tdk	BWI17_00405	BWI17_16220	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.972
dut	tmk	BWI17_00405	BWI17_15910	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.956
ndk	dcd	BWI17_12695	BWI17_19970	Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	dCTP deaminase; Catalyzes the deamination of dCTP to dUTP.	0.964
ndk	dut	BWI17_12695	BWI17_00405	Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	0.971
ndk	pyrG	BWI17_12695	BWI17_10250	Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.977
ndk	tmk	BWI17_12695	BWI17_15910	Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.969
pyrG	dcd	BWI17_10250	BWI17_19970	CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	dCTP deaminase; Catalyzes the deamination of dCTP to dUTP.	0.925
pyrG	ndk	BWI17_10250	BWI17_12695	CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.977
pyrG	tdk	BWI17_10250	BWI17_16220	CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.616
tdk	dcd	BWI17_16220	BWI17_19970	Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	dCTP deaminase; Catalyzes the deamination of dCTP to dUTP.	0.544
tdk	dut	BWI17_16220	BWI17_00405	Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	0.972
tdk	pyrG	BWI17_16220	BWI17_10250	Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.616
tdk	tmk	BWI17_16220	BWI17_15910	Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.973