STRINGSTRING
APV48381.1 APV48381.1 APV48391.1 APV48391.1 gpsA gpsA murB murB APV48589.1 APV48589.1 APV48649.1 APV48649.1 APV48653.1 APV48653.1 APV48726.1 APV48726.1 pdxA pdxA APV49029.1 APV49029.1 APV49031.1 APV49031.1 APV49088.1 APV49088.1 APV52312.1 APV52312.1 aroE aroE APV49356.1 APV49356.1 APV49407.1 APV49407.1 APV49416.1 APV49416.1 APV49450.1 APV49450.1 APV52349.1 APV52349.1 APV49583.1 APV49583.1 hisD hisD APV49797.1 APV49797.1 APV49840.1 APV49840.1 APV49897.1 APV49897.1 APV49950.1 APV49950.1 APV50032.1 APV50032.1 APV50176.1 APV50176.1 APV50183.1 APV50183.1 APV50243.1 APV50243.1 APV50321.1 APV50321.1 APV50343.1 APV50343.1 APV50391.1 APV50391.1 APV50639.1 APV50639.1 APV50649.1 APV50649.1 APV50675.1 APV50675.1 APV50701.1 APV50701.1 APV50722.1 APV50722.1 APV50725.1 APV50725.1 APV50850.1 APV50850.1 APV52469.1 APV52469.1 APV50920.1 APV50920.1 zwf zwf APV50999.1 APV50999.1 APV51014.1 APV51014.1 fabG fabG APV51044.1 APV51044.1 APV51140.1 APV51140.1 APV51145.1 APV51145.1 APV51231.1 APV51231.1 APV51254.1 APV51254.1 APV51269.1 APV51269.1 mdh mdh APV51509.1 APV51509.1 APV51512.1 APV51512.1 APV51526.1 APV51526.1 APV51528.1 APV51528.1 APV51537.1 APV51537.1 APV51577.1 APV51577.1 leuB leuB APV51622.1 APV51622.1 APV51686.1 APV51686.1 guaB guaB APV51810.1 APV51810.1 ilvC ilvC APV51893.1 APV51893.1 APV51933.1 APV51933.1 APV52588.1 APV52588.1 APV52100.1 APV52100.1 dxr dxr
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APV48381.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (798 aa)
APV48391.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (672 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (326 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (296 aa)
APV48589.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
APV48649.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (307 aa)
APV48653.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
APV48726.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (321 aa)
APV49029.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (698 aa)
APV49031.1Gluconate 5-dehydrogenase; Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
APV49088.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (294 aa)
APV52312.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa)
APV49356.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
APV49407.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
APV49416.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
APV49450.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
APV52349.1Gluconate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
APV49583.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa)
APV49797.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
APV49840.1Involved in pteridine salvage and antifolate resistance; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
APV49897.1D-glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)
APV49950.1Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
APV50032.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (312 aa)
APV50176.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (306 aa)
APV50183.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
APV50243.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
APV50321.1Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
APV50343.1NAD(P)-dependent oxidoreductase; Converts glucose to D-glucono-1,5 lactone; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
APV50391.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (235 aa)
APV50639.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (395 aa)
APV50649.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
APV50675.12-dehydropantoate 2-reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
APV50701.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
APV50722.1beta-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa)
APV50725.1beta-ketoacyl-ACP reductase; Catalyzes the conversion of 3-hydroxyacyl-CoA to 3-oxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
APV50850.12-deoxy-D-gluconate 3-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
APV52469.1Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
APV50920.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (485 aa)
APV50999.13-oxoacyl-[acyl-carrier-protein] reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
APV51014.1NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
fabG3-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
APV51044.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
APV51140.1Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
APV51145.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
APV51231.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (254 aa)
APV51254.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (324 aa)
APV51269.13-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa)
APV51509.1NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
APV51512.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (313 aa)
APV51526.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa)
APV51528.13-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
APV51537.1S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa)
APV51577.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (365 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (354 aa)
APV51622.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
APV51686.16-phosphogluconate dehydrogenase (decarboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (486 aa)
APV51810.1Isocitrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
APV51893.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
APV51933.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (254 aa)
APV52588.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa)
APV52100.13-hydroxybutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
dxr1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (395 aa)
Your Current Organism:
Betaproteobacteria bacterium GR1643
NCBI taxonomy Id: 1904640
Other names: B. bacterium GR16-43, Betaproteobacteria bacterium GR16-43, Nnibrrimonas geomnyongensis
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.