STRINGSTRING
purN purN APV48209.1 APV48209.1 APV48248.1 APV48248.1 APV48249.1 APV48249.1 APV48253.1 APV48253.1 purM purM APV48271.1 APV48271.1 dut dut APV48273.1 APV48273.1 APV48306.1 APV48306.1 APV48318.1 APV48318.1 rho rho APV52217.1 APV52217.1 APV48365.1 APV48365.1 rpoD rpoD dnaG dnaG APV52222.1 APV52222.1 bioB bioB bioF bioF bioH bioH bioC bioC bioD bioD APV48483.1 APV48483.1 pyrC pyrC APV48495.1 APV48495.1 coaX coaX APV52234.1 APV52234.1 APV52244.1 APV52244.1 APV48638.1 APV48638.1 APV48649.1 APV48649.1 APV48661.1 APV48661.1 queE queE APV48688.1 APV48688.1 APV52255.1 APV52255.1 APV48717.1 APV48717.1 trpC trpC trpD trpD trpE trpE apaG apaG pdxA pdxA APV48775.1 APV48775.1 prs prs coaD coaD rpoH rpoH ctaB ctaB coaE coaE hemA hemA APV48876.1 APV48876.1 APV48938.1 APV48938.1 hemF hemF purD purD purH purH APV48984.1 APV48984.1 polA polA APV49002.1 APV49002.1 APV49006.1 APV49006.1 proA proA nadD nadD APV49020.1 APV49020.1 proC proC rpoZ rpoZ gmk gmk APV49067.1 APV49067.1 thiG thiG APV49071.1 APV49071.1 APV49075.1 APV49075.1 APV49080.1 APV49080.1 APV49088.1 APV49088.1 APV49089.1 APV49089.1 thiC thiC APV52300.1 APV52300.1 APV49110.1 APV49110.1 thiE thiE hemL hemL APV49118.1 APV49118.1 APV49144.1 APV49144.1 atpB atpB atpE atpE atpF atpF atpH atpH atpA atpA atpG atpG atpD atpD atpC atpC glmU glmU priA priA hemE hemE APV49233.1 APV49233.1 APV49238.1 APV49238.1 APV49240.1 APV49240.1 APV49242.1 APV49242.1 hemC hemC APV49262.1 APV49262.1 pyrB pyrB APV49267.1 APV49267.1 lipA lipA pyrE pyrE APV49348.1 APV49348.1 APV49392.1 APV49392.1 APV49395.1 APV49395.1 APV49400.1 APV49400.1 APV49492.1 APV49492.1 APV49504.1 APV49504.1 APV49518.1 APV49518.1 APV52345.1 APV52345.1 APV49525.1 APV49525.1 APV49558.1 APV49558.1 dxs dxs APV52363.1 APV52363.1 purC purC APV49709.1 APV49709.1 folE2 folE2 murA murA nusG nusG rpoB rpoB rpoA rpoA APV49808.1 APV49808.1 APV49812.1 APV49812.1 APV52377.1 APV52377.1 APV49853.1 APV49853.1 APV49886.1 APV49886.1 APV49903.1 APV49903.1 APV49942.1 APV49942.1 carA carA carB carB APV52386.1 APV52386.1 APV50020.1 APV50020.1 pyrG pyrG queG queG kdsB kdsB adk adk tgt tgt proB proB APV52405.1 APV52405.1 APV50164.1 APV50164.1 APV50173.1 APV50173.1 APV50235.1 APV50235.1 APV50262.1 APV50262.1 APV50276.1 APV50276.1 ackA ackA APV52415.1 APV52415.1 BWI17_12020 BWI17_12020 APV50382.1 APV50382.1 APV50408.1 APV50408.1 APV50421.1 APV50421.1 APV52423.1 APV52423.1 APV50471.1 APV50471.1 APV50472.1 APV50472.1 accA accA ndk ndk purA purA priB priB APV50497.1 APV50497.1 APV50501.1 APV50501.1 APV50502.1 APV50502.1 APV50520.1 APV50520.1 APV50537.1 APV50537.1 dnaQ dnaQ pyrD pyrD APV50576.1 APV50576.1 APV50593.1 APV50593.1 mobA mobA fdhD fdhD moaA moaA APV50598.1 APV50598.1 APV50602.1 APV50602.1 APV50611.1 APV50611.1 APV50612.1 APV50612.1 APV50614.1 APV50614.1 APV52441.1 APV52441.1 serC serC APV50639.1 APV50639.1 cmk cmk pyrF pyrF APV50649.1 APV50649.1 hldD hldD nadE nadE purK purK purE purE serS serS APV50697.1 APV50697.1 APV50751.1 APV50751.1 APV50841.1 APV50841.1 APV50878.1 APV50878.1 APV52472.1 APV52472.1 BWI17_15315 BWI17_15315 pdxJ pdxJ APV50953.1 APV50953.1 APV50968.1 APV50968.1 upp upp APV52478.1 APV52478.1 APV50976.1 APV50976.1 APV50981.1 APV50981.1 APV50987.1 APV50987.1 folE folE APV52487.1 APV52487.1 tmk tmk APV51039.1 APV51039.1 APV51044.1 APV51044.1 APV51069.1 APV51069.1 tdk tdk dnaE2 dnaE2 APV51128.1 APV51128.1 APV51129.1 APV51129.1 APV51130.1 APV51130.1 APV51133.1 APV51133.1 APV51186.1 APV51186.1 APV51254.1 APV51254.1 APV51278.1 APV51278.1 APV51314.1 APV51314.1 folD folD APV51317.1 APV51317.1 APV51319.1 APV51319.1 APV51356.1 APV51356.1 fliA fliA APV51425.1 APV51425.1 APV51445.1 APV51445.1 APV51457.1 APV51457.1 APV51526.1 APV51526.1 trpF trpF thiL thiL nusB nusB ribH ribH ribB ribB APV51576.1 APV51576.1 APV51577.1 APV51577.1 APV51587.1 APV51587.1 nadK nadK hemH hemH purF purF APV51609.1 APV51609.1 accD accD trpA trpA trpB trpB trpF-2 trpF-2 APV51658.1 APV51658.1 dnaX dnaX kynU kynU APV51705.1 APV51705.1 moaC moaC APV51734.1 APV51734.1 APV51744.1 APV51744.1 cobD cobD dcd dcd APV51765.1 APV51765.1 guaA guaA guaB guaB nusA nusA thyA thyA APV51790.1 APV51790.1 queC queC APV51805.1 APV51805.1 APV51813.1 APV51813.1 APV52569.1 APV52569.1 acsA acsA APV52571.1 APV52571.1 APV51872.1 APV51872.1 APV52576.1 APV52576.1 APV52579.1 APV52579.1 ctaA ctaA APV51929.1 APV51929.1 APV52588.1 APV52588.1 APV51973.1 APV51973.1 APV52591.1 APV52591.1 APV51988.1 APV51988.1 napA napA APV52055.1 APV52055.1 APV52060.1 APV52060.1 APV52092.1 APV52092.1 APV52099.1 APV52099.1 APV52101.1 APV52101.1 APV52108.1 APV52108.1 pyrH pyrH APV52128.1 APV52128.1 APV52129.1 APV52129.1 queF queF APV52140.1 APV52140.1 pdxH pdxH APV52172.1 APV52172.1 APV52175.1 APV52175.1 purL purL APV52184.1 APV52184.1 queA queA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (213 aa)
APV48209.1uroporphyrinogen-III C-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
APV48248.1Deoxynucleoside kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
APV48249.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
APV48253.1Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (361 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
APV48271.1Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (407 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (149 aa)
APV48273.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
APV48306.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
APV48318.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (231 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (420 aa)
APV52217.1DUF4440 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
APV48365.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
rpoDRNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (639 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (593 aa)
APV52222.1Molybdopterin biosynthesis protein MoeB; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
bioBBiotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (336 aa)
bioF8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (393 aa)
bioHPimeloyl-[acyl-carrier protein] methyl ester esterase; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. (253 aa)
bioCMalonyl-[acyl-carrier protein] O-methyltransferase BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (287 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (232 aa)
APV48483.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (345 aa)
APV48495.1Isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
coaXHypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (244 aa)
APV52234.1Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (413 aa)
APV52244.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
APV48638.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
APV48649.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (307 aa)
APV48661.1Aspartate aminotransferase family protein; Catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
queE7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (218 aa)
APV48688.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
APV52255.1RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (233 aa)
APV48717.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
trpCIndole-3-glycerol-phosphate synthase; Involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (267 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (344 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (492 aa)
apaGCo2+/Mg2+ efflux protein ApaG; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (321 aa)
APV48775.1Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (167 aa)
rpoHRNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (283 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (299 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (206 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (421 aa)
APV48876.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
APV48938.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (129 aa)
hemFCoproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (293 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (429 aa)
purHBifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
APV48984.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (952 aa)
APV49002.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
APV49006.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (427 aa)
nadDHypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (218 aa)
APV49020.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ComB family. (244 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (73 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (204 aa)
APV49067.1YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (414 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (265 aa)
APV49071.1Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (70 aa)
APV49075.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
APV49080.1RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (480 aa)
APV49088.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (294 aa)
APV49089.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa)
thiCPhosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (637 aa)
APV52300.1Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
APV49110.1Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (220 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
APV49118.1Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (324 aa)
APV49144.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (367 aa)
atpBF0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (269 aa)
atpEATP F0F1 synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (90 aa)
atpFF0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (156 aa)
atpHHypothetical protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (178 aa)
atpAF0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (513 aa)
atpGF0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (291 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (472 aa)
atpCF0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (139 aa)
glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (439 aa)
priAHypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (661 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (351 aa)
APV49233.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa)
APV49238.1AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
APV49240.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
APV49242.1Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (259 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (312 aa)
APV49262.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (185 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (322 aa)
APV49267.1Dihydroorotase; Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology. (424 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (314 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (226 aa)
APV49348.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
APV49392.1TIGR00701 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
APV49395.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
APV49400.1Adenosylmethionine--8-amino-7-oxononanoate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (429 aa)
APV49492.1Glyxoylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
APV49504.1Aspartate aminotransferase family protein; Catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
APV49518.1MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
APV52345.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (688 aa)
APV49525.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
APV49558.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (64 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (631 aa)
APV52363.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (289 aa)
APV49709.1Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (310 aa)
folE2GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. (265 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (416 aa)
nusGTranscription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (177 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1357 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (325 aa)
APV49808.1Dihydroneopterin triphosphate diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Nudix hydrolase family. (152 aa)
APV49812.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa)
APV52377.1Adenylate/guanylate cyclase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
APV49853.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
APV49886.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
APV49903.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (165 aa)
APV49942.1Competence/damage-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
carACarbamoyl-phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
carBCarbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1069 aa)
APV52386.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (281 aa)
APV50020.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (178 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (556 aa)
queGtRNA epoxyqueuosine(34) reductase QueG; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (351 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (258 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (219 aa)
tgttRNA guanosine(34) transglycosylase Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose t [...] (375 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (372 aa)
APV52405.1Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (968 aa)
APV50164.1Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (388 aa)
APV50173.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
APV50235.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (212 aa)
APV50262.1DNA ligase D; Derived by automated computational analysis using gene prediction method: Protein Homology. (914 aa)
APV50276.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (417 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (348 aa)
APV52415.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
BWI17_12020LysR family transcriptional regulator; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)
APV50382.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (201 aa)
APV50408.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
APV50421.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (652 aa)
APV52423.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
APV50471.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa)
APV50472.1ATP:cob(I)alamin adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (181 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (321 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa)
priBPrimosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family. (101 aa)
APV50497.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (815 aa)
APV50501.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (295 aa)
APV50502.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
APV50520.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (186 aa)
APV50537.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)
dnaQDNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (235 aa)
pyrDDihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (342 aa)
APV50576.1uroporphyrinogen-III C-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (259 aa)
APV50593.1Molybdopterin molybdenumtransferase MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (422 aa)
mobAMolybdenum cofactor guanylyltransferase MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (194 aa)
fdhDSulfurtransferase FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (270 aa)
moaACyclic pyranopterin phosphate synthase MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (361 aa)
APV50598.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
APV50602.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (975 aa)
APV50611.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
APV50612.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
APV50614.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
APV52441.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (717 aa)
serCDNA gyrase subunit A; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (366 aa)
APV50639.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (395 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (236 aa)
APV50649.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
hldDADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (335 aa)
nadENAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (533 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (374 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (165 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (431 aa)
APV50697.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
APV50751.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
APV50841.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
APV50878.1Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (283 aa)
APV52472.1Carotenoid 1,2-hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
BWI17_15315L-aspartate oxidase; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa)
pdxJPyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (248 aa)
APV50953.12,5-diketo-D-gluconic acid reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
APV50968.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1303 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (213 aa)
APV52478.1Uracil phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
APV50976.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
APV50981.1Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (270 aa)
APV50987.1Adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
folEGTP cyclohydrolase I FolE; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
APV52487.1Aminodeoxychorismate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (206 aa)
APV51039.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
APV51044.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
APV51069.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
dnaE2Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1025 aa)
APV51128.1Molybdenum cofactor biosynthesis protein MoaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
APV51129.1Molybdopterin converting factor subunit 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
APV51130.1Molybdopterin-guanine dinucleotide biosynthesis protein B; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
APV51133.1Gluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
APV51186.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (648 aa)
APV51254.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (324 aa)
APV51278.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
APV51314.1Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
folDBifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa)
APV51317.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (644 aa)
APV51319.1propionate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (631 aa)
APV51356.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
fliARNA polymerase sigma factor FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (238 aa)
APV51425.1Flagellum-specific ATP synthase FliI; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
APV51445.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (446 aa)
APV51457.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (248 aa)
APV51526.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (229 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (324 aa)
nusBN utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (154 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (156 aa)
ribB3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (371 aa)
APV51576.1Riboflavin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
APV51577.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (365 aa)
APV51587.1Molybdopterin adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
nadKHypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (290 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (336 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (506 aa)
APV51609.1Bifunctional tetrahydrofolate synthase/dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. (417 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (271 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (397 aa)
trpF-2N-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (210 aa)
APV51658.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (549 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (403 aa)
APV51705.1DNA polymerase III subunit chi; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
moaCMolybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (159 aa)
APV51734.1Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (166 aa)
APV51744.14a-hydroxytetrahydrobiopterin dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
cobDHypothetical protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (306 aa)
dcddCTP deaminase; Catalyzes the deamination of dCTP to dUTP. (188 aa)
APV51765.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1139 aa)
guaAGlutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (525 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (486 aa)
nusATranscription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. (494 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
APV51790.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (163 aa)
queC7-cyano-7-deazaguanine synthase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (227 aa)
APV51805.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
APV51813.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (455 aa)
APV52569.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa)
APV52571.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (558 aa)
APV51872.1MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
APV52576.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
APV52579.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (667 aa)
ctaAHeme A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. (354 aa)
APV51929.1Helix-turn-helix transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
APV52588.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa)
APV51973.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (108 aa)
APV52591.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (216 aa)
APV51988.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
napANitrate reductase catalytic subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (842 aa)
APV52055.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
APV52060.1Oxygen-independent coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (473 aa)
APV52092.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
APV52099.1acetoacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (650 aa)
APV52101.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
APV52108.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (231 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (249 aa)
APV52128.1Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. (249 aa)
APV52129.1Hypoxanthine-guanine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
queFNADPH-dependent 7-cyano-7-deazaguanine reductase QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (138 aa)
APV52140.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (201 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (210 aa)
APV52172.1BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (88 aa)
APV52175.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1325 aa)
APV52184.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
queAtRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (341 aa)
Your Current Organism:
Betaproteobacteria bacterium GR1643
NCBI taxonomy Id: 1904640
Other names: B. bacterium GR16-43, Betaproteobacteria bacterium GR16-43, Nnibrrimonas geomnyongensis
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