STRINGSTRING
XCC1539 XCC1539 XCC0380 XCC0380 virB1 virB1 mrsA mrsA dniR-2 dniR-2 murD murD XCC2739 XCC2739 XCC2784 XCC2784 murA murA mtgA mtgA ponB ponB XCC3210 XCC3210 mrcA mrcA mpl mpl slt slt dacC dacC rlpA rlpA mrdB mrdB mrdA mrdA XCC3805 XCC3805 XCC1692 XCC1692 amiC amiC murB murB XCC1804 XCC1804 rfb303 rfb303 amiC-2 amiC-2 yjbJ yjbJ ddlB ddlB bacA bacA glmU glmU XCC0711 XCC0711 ftsI ftsI murE murE murF murF mraY mraY anmK anmK XCC3808 XCC3808 ftsW ftsW murG murG murC murC ddlB-2 ddlB-2 XCC0936 XCC0936 mltG mltG pbpC pbpC mviN mviN hpa2 hpa2 nagZ nagZ XCC1314 XCC1314 uppS uppS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XCC1539Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (191 aa)
XCC0380Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (205 aa)
virB1VirB1 protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (277 aa)
mrsAPhosphohexose mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (449 aa)
dniR-2Membrane-bound lytic murein transglycosylase D precursor; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (471 aa)
murDUDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine. Belongs to the MurCDEF family. MurD2 subfamily. (468 aa)
XCC2739Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (451 aa)
XCC2784Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (345 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (424 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (246 aa)
ponBPenicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (814 aa)
XCC3210Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (324 aa)
mrcAPenicillin-binding protein 1A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (840 aa)
mplUDP-N-acetylmuramate-L-alanine ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (452 aa)
sltSoluble lytic murein transglycosylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (677 aa)
dacCPenicillin-binding protein 6; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the peptidase S11 family. (403 aa)
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (448 aa)
mrdBRod shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (372 aa)
mrdAPenicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (686 aa)
XCC3805N-acetylmuramoyl-L-alanine amidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (266 aa)
XCC1692Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (253 aa)
amiCN-acetylmuramoyl-L-alanine amidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (386 aa)
murBUDP-N-acetylpyruvoylglucosamine reductase; Cell wall formation. (350 aa)
XCC1804Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (246 aa)
rfb303Lipopolysaccharide core biosynthesis protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (324 aa)
amiC-2N-acetylmuramoyl-L-alanine amidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (563 aa)
yjbJSoluble lytic murein transglycosylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (322 aa)
ddlBD-alanine-D-alanine ligase A; Cell wall formation. (373 aa)
bacAUndecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (263 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (454 aa)
XCC0711Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (576 aa)
ftsIPenicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (623 aa)
murEUDP-N-acetylmuramoylalanyl-D- glutamate-2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (495 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (494 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (361 aa)
anmKConserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (377 aa)
XCC3808Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (258 aa)
ftsWCell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (454 aa)
murGUDP-N-acetylglucosamine-N- acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (427 aa)
murCUDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (477 aa)
ddlB-2D-alanine-D-alanine ligase B; Cell wall formation. (318 aa)
XCC0936Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (170 aa)
mltGConserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (352 aa)
pbpCBifunctional penicillin-binding protein 1C; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (807 aa)
mviNVirulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (530 aa)
hpa2Hpa2 protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (138 aa)
nagZN-acetyl-beta-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (331 aa)
XCC1314Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (351 aa)
uppSUndecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (258 aa)
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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