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pgsA pgsA cls cls XCC0179 XCC0179 gpdA gpdA XCC0228 XCC0228 clsB clsB XCC0458 XCC0458 XCC0471 XCC0471 pgsA-2 pgsA-2 XCC0505 XCC0505 glmU glmU wxcL wxcL pssA pssA lpxC lpxC dgkA dgkA ipk ipk lpxH lpxH acpP acpP XCC1119 XCC1119 lytB lytB cicA cicA lpxB lpxB lpxA lpxA fabZ fabZ lpxD lpxD dxr dxr cdsA-2 cdsA-2 XCC1635 XCC1635 cdh-2 cdh-2 ispD ispD ispF ispF ispG ispG XCC1782 XCC1782 pgsA-3 pgsA-3 lpxK lpxK pssA-2 pssA-2 suhB suhB avrXccA2 avrXccA2 dxs dxs dpsD dpsD ispA ispA gtrB-4 gtrB-4 cysQ cysQ XCC3133 XCC3133 htrB htrB XCC3746 XCC3746 dpm1 dpm1 XCC3855 XCC3855 plsC plsC cls-4 cls-4 plsB plsB cls-5 cls-5 avrXccA1 avrXccA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pgsACDP-alcohol phosphatidyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (204 aa)
clsCardiolipin synthetase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (486 aa)
XCC0179Acetyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (267 aa)
gpdAGlycerol-3-phosphate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (341 aa)
XCC0228Acyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (209 aa)
clsBPhospholipase; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (339 aa)
XCC0458Conserved hypothetical protein; Probably phosphorylates lipids; the in vivo substrate is unknown. (309 aa)
XCC0471Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (238 aa)
pgsA-2CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase-related protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (222 aa)
XCC0505Acyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (210 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (454 aa)
wxcLGlycosyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (323 aa)
pssAPhosphatidylserine synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (257 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (303 aa)
dgkADiacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (126 aa)
ipk4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (295 aa)
lpxHConserved hypothetical protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (247 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (79 aa)
XCC1119Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (588 aa)
lytBPenicillin tolerance protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (316 aa)
cicAPhosphotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (196 aa)
lpxBLipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (398 aa)
lpxAUDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (263 aa)
fabZ(3r)-hydroxymyristoyl ACP dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (153 aa)
lpxDUDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (337 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (396 aa)
cdsA-2Phosphatidate cytidylyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDS family. (275 aa)
XCC1635Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (1028 aa)
cdh-2CDP-diacylglycerol pyrophosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (261 aa)
ispD4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (265 aa)
ispF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (163 aa)
ispGConserved hypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (421 aa)
XCC1782Phosphatidylglycerophosphatase B-related protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (243 aa)
pgsA-3CDP-diacylglycerol-glycerol-3- phosphate 3-phosphatidyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (210 aa)
lpxKLipid A 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (351 aa)
pssA-2CDP-diacylglycerol-serine o-phosphatidyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (198 aa)
suhBExtragenic supressor protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the inositol monophosphatase superfamily. (277 aa)
avrXccA2Avirulence protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (495 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (693 aa)
dpsDPhosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (282 aa)
ispAGeranyltranstransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. (291 aa)
gtrB-4Glucosyl transferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (347 aa)
cysQSulfite synthesis pathway protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (261 aa)
XCC3133DNA helicase related protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (1087 aa)
htrBLipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (306 aa)
XCC3746Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (556 aa)
dpm1Dolichol-phosphate mannosyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (240 aa)
XCC3855Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (113 aa)
plsCAcyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (249 aa)
cls-4Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (474 aa)
plsBGlycerol-3-phosphate acyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the GPAT/DAPAT family. (889 aa)
cls-5Cardiolipin synthetase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (405 aa)
avrXccA1Avirulence protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (623 aa)
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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