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| | XCC1931 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (347 aa) |
| | fliI | Flagellar protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (458 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (1080 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarA family. (375 aa) |
| | pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (351 aa) |
| | XCC1782 | Phosphatidylglycerophosphatase B-related protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (243 aa) |
| | ispG | Conserved hypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (421 aa) |
| | folE2 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. (311 aa) |
| | thiD | Phosphomethylpyrimidine kinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (276 aa) |
| | XCC1718 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CinA family. (162 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (163 aa) |
| | ispD | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (265 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (563 aa) |
| | cdh-2 | CDP-diacylglycerol pyrophosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (261 aa) |
| | XCC1635 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (1028 aa) |
| | haaO | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (176 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (424 aa) |
| | kmo | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (456 aa) |
| | nadK | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (258 aa) |
| | purB | Adenylosuccinate lyase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (455 aa) |
| | pdxY | Pyridoxine kinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (302 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa) |
| | cdsA-2 | Phosphatidate cytidylyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDS family. (275 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (396 aa) |
| | lpxD | UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (337 aa) |
| | fabZ | (3r)-hydroxymyristoyl ACP dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (153 aa) |
| | lpxA | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (263 aa) |
| | lpxB | Lipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (398 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | cicA | Phosphotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (196 aa) |
| | XCC1287 | Oxidoreductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (423 aa) |
| | hpt | Hypoxanthine-guanine phosphoribosyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (184 aa) |
| | hrcN | HrpB6 protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (442 aa) |
| | lytB | Penicillin tolerance protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (316 aa) |
| | ribF | Riboflavin biosynthesis protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the ribF family. (362 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (400 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (167 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa) |
| | dxs | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (693 aa) |
| | avrXccA2 | Avirulence protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (495 aa) |
| | kdtB | Lipopolysaccharide synthesis enzyme; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (168 aa) |
| | upp | Putative UMP pyrophosphorylase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (210 aa) |
| | fdsC | Formate dehydrogenase b chain; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (281 aa) |
| | XCC2353 | Conserved hypothetical protein; Putative; ORF located using Glimmer/Genemark. (95 aa) |
| | ybeX | Polar amino acid transporter; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (292 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (186 aa) |
| | acs | Acetyl coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (647 aa) |
| | plsB | Glycerol-3-phosphate acyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the GPAT/DAPAT family. (889 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (243 aa) |
| | tdk | Thymidine kinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (209 aa) |
| | folE | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (209 aa) |
| | avrXccA1 | Avirulence protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (623 aa) |
| | cls-5 | Cardiolipin synthetase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (405 aa) |
| | dut | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (152 aa) |
| | XCC3855 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (113 aa) |
| | dpm1 | Dolichol-phosphate mannosyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (240 aa) |
| | pyrE | Orotate phosphoribosyl transferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (219 aa) |
| | XCC3791 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (274 aa) |
| | XCC3746 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (556 aa) |
| | mdcB | Beta subunit of malonate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (304 aa) |
| | pbeF | pre-B cell enhancing factor related protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the NAPRTase family. (468 aa) |
| | htrB | Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (306 aa) |
| | thiC | Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (625 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (187 aa) |
| | thiE | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (207 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (203 aa) |
| | dfp | DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (419 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (227 aa) |
| | baf | Transcriptional regulator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (242 aa) |
| | nrdB | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (347 aa) |
| | plsC | Acyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (249 aa) |
| | XCC4015 | AMP-ligase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (511 aa) |
| | cls-4 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (474 aa) |
| | XCC0735 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (122 aa) |
| | lpxC | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (303 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (324 aa) |
| | pncB | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (398 aa) |
| | purL | Phosphoribosylformylglycinamidine synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1348 aa) |
| | pssA | Phosphatidylserine synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (257 aa) |
| | wxcL | Glycosyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (323 aa) |
| | glmU | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (454 aa) |
| | atpC | ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. (140 aa) |
| | atpD | ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (468 aa) |
| | atpG | ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (287 aa) |
| | atpA | ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (515 aa) |
| | atpH | ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (175 aa) |
| | atpF | ATP synthase B chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (156 aa) |
| | atpE | ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (100 aa) |
| | atpB | ATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (266 aa) |
| | accC-2 | Biotin carboxylase subunit of acetyl CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa) |
| | XCC0505 | Acyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (210 aa) |
| | pgsA-2 | CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase-related protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (222 aa) |
| | pgsA | CDP-alcohol phosphatidyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (204 aa) |
| | purH | Bifunctional purine biosynthesis protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (527 aa) |
| | purD | Phosphoribosylamine-glycine ligase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (431 aa) |
| | XCC0471 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (238 aa) |
| | XCC0458 | Conserved hypothetical protein; Probably phosphorylates lipids; the in vivo substrate is unknown. (309 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the SAICAR synthetase family. (310 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (289 aa) |
| | clsB | Phospholipase; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (339 aa) |
| | XCC0228 | Acyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (209 aa) |
| | gpdA | Glycerol-3-phosphate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (341 aa) |
| | XCC0179 | Acetyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (267 aa) |
| | cls | Cardiolipin synthetase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (486 aa) |
| | nadC | Nicotinate-nucleotide pyrophosphorylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the NadC/ModD family. (290 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) |
| | accD-2 | Acetyl-coenzyme A carboxylase carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (295 aa) |
| | dpsD | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (282 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (189 aa) |
| | ispA | Geranyltranstransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. (291 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (299 aa) |
| | XCC2725 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (209 aa) |
| | pyrB | Aspartate carbamoyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (315 aa) |
| | algH | Transcriptional regulator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the UPF0301 (AlgH) family. (188 aa) |
| | purM | Phosphoribosylformylglycinamide cyclo-ligase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (341 aa) |
| | purN | 5'-phosphoribosylglycinamide transformylase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (217 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (199 aa) |
| | gtrB-4 | Glucosyl transferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (347 aa) |
| | cysQ | Sulfite synthesis pathway protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (261 aa) |
| | XCC3051 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (429 aa) |
| | nadE | NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (552 aa) |
| | coaE | Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (207 aa) |
| | XCC3133 | DNA helicase related protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (1087 aa) |
| | XCC3149 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (66 aa) |
| | thiG | Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (264 aa) |
| | spoT | Pentaphosphate guanosine-3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (723 aa) |
| | suhB | Extragenic supressor protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the inositol monophosphatase superfamily. (277 aa) |
| | pyrC | Dihydroorotase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (449 aa) |
| | cmk | Cytidylate kinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (226 aa) |
| | folD | Bifunctional methylenetetrahydrofolate dehydrogenase/ methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa) |
| | guaA | Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. (521 aa) |
| | dgkA | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (126 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) |
| | pdxA | Pyridoxal phosphate biosynthetic protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (322 aa) |
| | moaB | Molybdopterin biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (172 aa) |
| | ipk | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (295 aa) |
| | prsA | Phosphoribosyl pyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (319 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (488 aa) |
| | lpxH | Conserved hypothetical protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (247 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (339 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (165 aa) |
| | moaD | Molybdopterin-converting factor chain 1; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (81 aa) |
| | moaE | Molybdopterin-converting factor chain 2; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (145 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (79 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa) |
| | XCC1087 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (212 aa) |
| | XCC1119 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (588 aa) |
| | pssA-2 | CDP-diacylglycerol-serine o-phosphatidyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (198 aa) |
| | lpxK | Lipid A 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (351 aa) |
| | pgsA-3 | CDP-diacylglycerol-glycerol-3- phosphate 3-phosphatidyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (210 aa) |
| | mobA | Molybdopterin guanine dinucleotide synthase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (192 aa) |
| | moeA-2 | Molybdopterin biosynthesis; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (416 aa) |
| | moeA | Molybdopterin biosynthesis; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (406 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa) |
