STRINGSTRING
recG recG W5S_0076 W5S_0076 W5S_0089 W5S_0089 W5S_0133 W5S_0133 hslU hslU zapE zapE W5S_0469 W5S_0469 W5S_0519 W5S_0519 ftsH ftsH deaD deaD W5S_0788 W5S_0788 clpV clpV clpB clpB srmB srmB hscA hscA dbpA dbpA W5S_1580 W5S_1580 W5S_1664 W5S_1664 W5S_1665 W5S_1665 W5S_1670 W5S_1670 fliI fliI W5S_1824 W5S_1824 W5S_1833 W5S_1833 W5S_1923 W5S_1923 W5S_1934 W5S_1934 W5S_2011 W5S_2011 ruvA ruvA ruvB ruvB minD minD ychF ychF W5S_2422 W5S_2422 btuD btuD W5S_2835 W5S_2835 dinG dinG rhlE rhlE uvrB uvrB W5S_3032 W5S_3032 W5S_3218 W5S_3218 htpG htpG lon lon clpX clpX recB recB W5S_3469 W5S_3469 W5S_3480 W5S_3480 W5S_3555 W5S_3555 W5S_3556 W5S_3556 W5S_3777 W5S_3777 uvrA uvrA W5S_4019 W5S_4019 mutL mutL W5S_4074 W5S_4074 W5S_4311 W5S_4311 W5S_4319 W5S_4319 rhlB rhlB rep rep ravA ravA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (704 aa)
W5S_0076Uncharacterized protein. (69 aa)
W5S_0089Lead cadmium zinc and mercury transporting ATPase. (784 aa)
W5S_0133YehL protein. (369 aa)
hslUATP-dependent protease ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (443 aa)
zapECell division protein ZapE; Reduces the stability of FtsZ polymers in the presence of ATP. (383 aa)
W5S_0469Molecular chaperone HSP90 family-like protein. (1051 aa)
W5S_0519Magnesium-translocating P-type ATPase. (903 aa)
ftsHATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (651 aa)
deaDATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (632 aa)
W5S_0788Pilus assembly protein cpaE. (399 aa)
clpVType VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. (865 aa)
clpBChaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (858 aa)
srmBATP-dependent RNA helicase SrmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (441 aa)
hscAChaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. (616 aa)
dbpAATP-dependent RNA helicase DbpA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. (490 aa)
W5S_1580Immunoglobulin-binding protein EibF. (428 aa)
W5S_1664UvrD-helicase domain-containing protein. (129 aa)
W5S_1665DNA helicase. (409 aa)
W5S_1670DNA helicase. (715 aa)
fliIFlagellum-specific ATP synthase FliI. (456 aa)
W5S_1824EA59 gene protein, phage lambda. (434 aa)
W5S_1833Uncharacterized protein. (483 aa)
W5S_1923ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. (757 aa)
W5S_1934Replication-associated recombination protein A. (447 aa)
W5S_2011ABC transporter ATP-binding protein uup. (636 aa)
ruvAHolliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (205 aa)
ruvBHolliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa)
minDSeptum site-determining protein MinD. (270 aa)
ychFRibosome-binding ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa)
W5S_2422Type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. (869 aa)
btuDVitamin B12 import ATP-binding protein BtuD; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (242 aa)
W5S_2835DNA helicase. (685 aa)
dinGATP-dependent DNA helicase DinG; DNA-dependent ATPase and 5'-3' DNA helicase. (699 aa)
rhlEATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (476 aa)
uvrBUvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (670 aa)
W5S_3032Iron-sulfur cluster carrier protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (369 aa)
W5S_3218Copper-translocating P-type ATPase. (907 aa)
htpGChaperone protein HtpG; Molecular chaperone. Has ATPase activity. (629 aa)
lonLon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (793 aa)
clpXATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (424 aa)
recBRecBCD enzyme subunit RecB; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holo [...] (1203 aa)
W5S_3469Arsenical pump-driving ATPase; Anion-transporting ATPase; Belongs to the arsA ATPase family. (588 aa)
W5S_3480ATPase. (211 aa)
W5S_3555Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (405 aa)
W5S_3556Replicative DNA helicase. (49 aa)
W5S_3777Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (468 aa)
uvrAUvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (944 aa)
W5S_4019Energy-dependent translational throttle protein EttA. (555 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (661 aa)
W5S_4074YhgE protein. (549 aa)
W5S_4311ATP-dependent DNA helicase RecQ. (608 aa)
W5S_4319DNA helicase. (720 aa)
rhlBATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (430 aa)
repATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (673 aa)
ravAATPase RavA; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone; Belongs to the RavA family. (499 aa)
Your Current Organism:
Pectobacterium parmentieri
NCBI taxonomy Id: 1905730
Other names: CFBP 8475, LMG 29774, LMG:29774, P. parmentieri, Pectobacterium parmentieri Khayi et al. 2016, Pectobacterium sp. SCC3193, strain RNS 08-42-1A, strain RNS 08.42.1A
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.