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W5S_1524 | Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (476 aa) | ||||
W5S_1600 | Cytosine-specific methyltransferase. (338 aa) | ||||
W5S_1716 | D-cysteine desulfhydrase. (337 aa) | ||||
rimK | Probable alpha-L-glutamate ligase; Belongs to the RimK family. (303 aa) | ||||
serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa) | ||||
W5S_2002 | Aminotransferase. (396 aa) | ||||
W5S_2072 | Hepatocellular carcinoma-associated protein p28-II. (121 aa) | ||||
W5S_2084 | Free methionine-(R)-sulfoxide reductase fRMsr. (168 aa) | ||||
W5S_2106 | Electron transport protein YccM. (368 aa) | ||||
W5S_2163 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa) | ||||
W5S_2405 | Phospholipase A accessory protein. (247 aa) | ||||
W5S_2406 | Fibronectin type 3 and ankyrin repeat domains 1 protein. (224 aa) | ||||
W5S_2697 | Ferredoxin-type protein NapH. (287 aa) | ||||
W5S_2832 | CoA-binding domain protein. (137 aa) | ||||
W5S_2911 | Homocysteine S-methyltransferase. (313 aa) | ||||
W5S_3253 | Putative siderophore biosynthesis protein SbnA. (358 aa) | ||||
W5S_3295 | Methionine synthase vitamin-B12 independent. (368 aa) | ||||
W5S_3571 | Ankyrin domain protein. (716 aa) | ||||
W5S_3572 | Ankyrin domain protein. (679 aa) | ||||
mtnK | Methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (400 aa) | ||||
mtnA | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (342 aa) | ||||
mtnD-2 | Acireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (181 aa) | ||||
mtnC | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (229 aa) | ||||
mtnB | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (205 aa) | ||||
W5S_3782 | Aromatic-amino-acid transaminase. (397 aa) | ||||
W5S_3833 | ATP-grasp domain family. (347 aa) | ||||
ksgA | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (272 aa) | ||||
W5S_4010 | Bifunctional aspartokinase/homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family. (819 aa) | ||||
W5S_4022 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa) | ||||
metK | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (383 aa) | ||||
gshB | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. (319 aa) | ||||
W5S_4103 | Aspartokinase; Belongs to the aspartokinase family. (458 aa) | ||||
W5S_4107 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1227 aa) | ||||
metAS | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. (309 aa) | ||||
W5S_4235 | Uncharacterized protein. (42 aa) | ||||
metK-2 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (392 aa) | ||||
asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (367 aa) | ||||
ilvE | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (308 aa) | ||||
W5S_4428 | Ankyrin repeat protein. (232 aa) | ||||
W5S_4429 | Phospholipase A accessory protein. (232 aa) | ||||
W5S_4430 | Ankyrin repeat protein. (232 aa) | ||||
W5S_4431 | Ankyrin repeat domain-containing protein. (232 aa) | ||||
metE | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (754 aa) | ||||
W5S_4512 | Serine acetyltransferase. (273 aa) | ||||
W5S_4515 | Rhodanese-like domain-containing protein. (143 aa) | ||||
expI | Acyl-homoserine-lactone synthase; Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone), an autoinducer molecule which binds to ExpR and thus acts in virulence (soft rot disease) through the activation of genes for plant tissue macerating enzymes. (217 aa) | ||||
W5S_0192 | O-succinylhomoserine (Thiol)-lyase. (386 aa) | ||||
metL | Bifunctional aspartokinase/homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family. (811 aa) | ||||
W5S_0394 | Cystathionine beta-lyase. (396 aa) | ||||
W5S_0442 | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. (366 aa) | ||||
W5S_0468 | Helix-turn-helix motif harboring transcription regulator protein. (107 aa) | ||||
W5S_0567 | Putative transcriptional regulator with C-terminal CBS domains. (103 aa) | ||||
W5S_0613 | Serine acetyltransferase. (166 aa) | ||||
mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (311 aa) | ||||
W5S_0820 | Aminotransferase class V-fold PLP-dependent enzyme. (426 aa) | ||||
W5S_0898 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (293 aa) | ||||
W5S_0906 | Cysteine synthase. (203 aa) | ||||
W5S_0942 | 3-mercaptopyruvate sulfurtransferase. (289 aa) | ||||
W5S_0947 | Cystathionine beta-lyase. (389 aa) | ||||
gshA | Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (517 aa) | ||||
luxS | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (171 aa) | ||||
mtnN | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulatio [...] (232 aa) | ||||
W5S_1163 | 3-mercaptopyruvate sulfurtransferase. (289 aa) | ||||
W5S_1276 | Putative methylcobalamin:homocysteine methyltransferase. (343 aa) | ||||
W5S_1290 | Putative aminotransferase yfdZ. (413 aa) | ||||
W5S_1348 | Aspartate-semialdehyde dehydrogenase family protein; Belongs to the aspartate-semialdehyde dehydrogenase family. (336 aa) | ||||
mtnD | Acireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (173 aa) |