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argG argG leuB leuB leuD leuD leuC leuC asd asd dapD dapD argB argB CC_0393 CC_0393 CC_0524 CC_0524 metXA metXA argD1 argD1 CC_0843 CC_0843 dapA dapA argC argC CC_1383 CC_1383 CC_1421 CC_1421 leuA leuA CC_2082 CC_2082 CC_2097 CC_2097 CC_2100 CC_2100 IlvH IlvH ilvC ilvC argH argH lysA lysA argF argF argD2 argD2 ilvE ilvE ilvD ilvD argJ argJ CC_3105 CC_3105 CC_3108 CC_3108 CC_3204 CC_3204 CC_3215 CC_3215 CC_3216 CC_3216 thrB thrB CC_3399 CC_3399 asd-2 asd-2 dapB dapB CC_3631 CC_3631 CC_3635 CC_3635 dapF dapF
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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argGArgininosuccinate synthase; Identified by match to TIGR protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (408 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (350 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (202 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (479 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (342 aa)
dapD2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Identified by match to protein family HMM; Belongs to the transferase hexapeptide repeat family. (283 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (304 aa)
CC_0393Thiamine-pyrophosphate-requiring enzyme; Identified by match to protein family HMM. (512 aa)
CC_0524Conserved hypothetical protein; Identified by Glimmer2; putative. (221 aa)
metXAHomoserine O-acetyltransferase, putative; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (382 aa)
argD1Succinylornithine transaminase, putative; Identified by match to protein family HMM; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (392 aa)
CC_0843Aspartokinase; Identified by match to TIGR protein family HMM TIGR00656; Belongs to the aspartokinase family. (415 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (317 aa)
CC_1383Homoserine dehydrogenase; Identified by match to PFAM protein family HMM PF00742. (429 aa)
CC_1421Dehydratase, IlvD/Edd family; Identified by match to PFAM protein family HMM PF00920; Belongs to the IlvD/Edd family. (600 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (524 aa)
CC_2082Identified by match to protein family HMM; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (353 aa)
CC_2097Phosphoserine phosphatase; Identified by match to TIGR protein family HMM TIGR00338. (296 aa)
CC_2100Acetolactate synthase, large subunit; Identified by match to TIGR protein family HMM TIGR00118. (582 aa)
IlvHAcetolactate synthase, small subunit; Identified by match to TIGR protein family HMM TIGR00119. (185 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
argHArgininosuccinate lyase; Identified by match to TIGR protein family HMM TIGR00838. (442 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa)
argFOrnithine carbamoyltransferase, anabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (311 aa)
argD2Acetylornithine aminotransferase; Identified by match to protein family HMM; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (296 aa)
ilvDDihydroxy-acid dehydratase; Identified by match to TIGR protein family HMM TIGR00110. (617 aa)
argJGlutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (403 aa)
CC_3105Threonine dehydratase; Identified by match to protein family HMM. (325 aa)
CC_3108L-serine dehydratase; Identified by match to TIGR protein family HMM TIGR00720; Belongs to the iron-sulfur dependent L-serine dehydratase family. (462 aa)
CC_3204Hydrolase, alpha/beta hydrolase fold family; Identified by match to protein family HMM; Belongs to the AB hydrolase superfamily. MetX family. (358 aa)
CC_3215D-3-phosphoglycerate dehydrogenase; Identified by match to PFAM protein family HMM PF00389; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa)
CC_3216Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (396 aa)
thrBHomoserine kinase; Similar to GP:6647291; identified by sequence similarity; putative; Belongs to the pseudomonas-type ThrB family. (317 aa)
CC_3399Threonine synthase; Identified by match to TIGR protein family HMM TIGR00260. (465 aa)
asd-2Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (348 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (257 aa)
CC_3631Acetylornithine deacetylase; Identified by match to protein family HMM. (391 aa)
CC_3635Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (400 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (288 aa)
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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