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| | CC_2128 | Gluconolactonase, putative; Similar to SP:Q01578 GB:X67189 PID:48655; identified by sequence similarity; putative. (303 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase; Identified by match to PFAM protein family HMM PF01503. (107 aa) |
| | hisF | hisF protein (cyclase); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). (260 aa) |
| | hisA | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to TIGR protein family HMM TIGR00007. (241 aa) |
| | hisH | Amidotransferase HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity). (213 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Identified by match to PFAM protein family HMM PF00475. (196 aa) |
| | fabA | 3-hydroxydecanoyl-(acyl-carrier-protein) dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (170 aa) |
| | CC_3719 | 3-oxoacyl-(acyl-carrier-protein) synthase I; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (403 aa) |
| | CC_3717 | Enoyl-(acyl-carrier-protein) reductase; Identified by match to protein family HMM. (278 aa) |
| | CC_3697 | Transcriptional regulator, LysR family; Identified by match to protein family HMM; Belongs to the LysR transcriptional regulatory family. (300 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (288 aa) |
| | CC_3635 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (400 aa) |
| | CC_3631 | Acetylornithine deacetylase; Identified by match to protein family HMM. (391 aa) |
| | CC_3625 | Cysteine synthase; Identified by match to protein family HMM. (328 aa) |
| | CC_3607 | Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645. (1508 aa) |
| | CC_3606 | Glutamate synthase, small subunit; Identified by match to protein family HMM. (481 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (443 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (257 aa) |
| | usg | Usg protein; Probably necessary for the cotranslation of trpF. It may also function as a subunit or stabilizer of phosphoribosylanthranilate isomerase (trpF). (89 aa) |
| | trpF | N-(5'-phosphoribosyl)-anthranilate isomerase; Identified by match to protein family HMM; Belongs to the TrpF family. (219 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (410 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (275 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (307 aa) |
| | CC_3541 | FolC bifunctional protein; Identified by match to protein family HMM; Belongs to the folylpolyglutamate synthase family. (437 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (341 aa) |
| | HisZ | Hypothetical protein; Identified by Glimmer2; putative. (386 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (320 aa) |
| | asd-2 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (348 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (413 aa) |
| | CC_3428 | Oxidoreductase, aldo/keto reductase family; Identified by match to protein family HMM. (279 aa) |
| | CC_3399 | Threonine synthase; Identified by match to TIGR protein family HMM TIGR00260. (465 aa) |
| | thrB | Homoserine kinase; Similar to GP:6647291; identified by sequence similarity; putative; Belongs to the pseudomonas-type ThrB family. (317 aa) |
| | CC_3293 | Alcohol dehydrogenase zinc-containing; Identified by match to protein family HMM. (320 aa) |
| | CC_3239 | Peptidase, M20/M25/M40 family; Identified by match to protein family HMM. (474 aa) |
| | CC_3224 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (274 aa) |
| | CC_3216 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (396 aa) |
| | CC_3215 | D-3-phosphoglycerate dehydrogenase; Identified by match to PFAM protein family HMM PF00389; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa) |
| | CC_3204 | Hydrolase, alpha/beta hydrolase fold family; Identified by match to protein family HMM; Belongs to the AB hydrolase superfamily. MetX family. (358 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (372 aa) |
| | CC_3143 | Omega-amino acid--pyruvate aminotransferase; Identified by match to protein family HMM; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa) |
| | CC_3132 | Aminotransferase, class III; Identified by match to protein family HMM; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (467 aa) |
| | argJ | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (403 aa) |
| | CC_3063 | Sulfite reductase (NADPH) flavoprotein alpha-component; Identified by match to protein family HMM. (504 aa) |
| | ilvR | Isoleucine biosynthesis transcriptional activator; Positively regulates the expression of the ilvD gene while negatively autoregulating its own expression. (296 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Identified by match to TIGR protein family HMM TIGR00110. (617 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (370 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (200 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa) |
| | CC_2968 | Hypothetical protein; Identified by Glimmer2; putative. (365 aa) |
| | CC_2952 | 4-amino-4-deoxychorismate lyase, putative; Identified by match to PFAM protein family HMM PF01063. (251 aa) |
| | CC_2933 | Prephenate dehydratase; Identified by match to PFAM protein family HMM PF00800. (283 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (296 aa) |
| | nadA | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (377 aa) |
| | carB | Carbamoyl-phosphate synthase, large subunit; Identified by match to PFAM protein family HMM PF00289. (1099 aa) |
| | carA | Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM; Belongs to the CarA family. (388 aa) |
| | CC_2711 | Hypothetical protein; Identified by Glimmer2; putative. (585 aa) |
| | CC_2651 | Serine acetyltransferase; Identified by match to protein family HMM. (279 aa) |
| | CC_2603 | N-carbamyl-L-amino acid amidohydrolase; Identified by match to protein family HMM. (427 aa) |
| | hisC2 | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (378 aa) |
| | CC_2382 | UDP-glucose 6-dehydrogenase; Identified by match to PFAM protein family HMM PF00984. (435 aa) |
| | CC_2379 | UDP-glucose 6-dehydrogenase; Identified by match to PFAM protein family HMM PF00984. (435 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (428 aa) |
| | gph | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (237 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (118 aa) |
| | CC_2266 | Identified by match to PFAM protein family HMM PF01048. (299 aa) |
| | argD2 | Acetylornithine aminotransferase; Identified by match to protein family HMM; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa) |
| | argF | Ornithine carbamoyltransferase, anabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (311 aa) |
| | CC_2224 | Cyclohexadienyl dehydrogenase; Identified by match to PFAM protein family HMM PF02153. (312 aa) |
| | hisC1 | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (359 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa) |
| | argH | Argininosuccinate lyase; Identified by match to TIGR protein family HMM TIGR00838. (442 aa) |
| | CC_2170 | propionyl-CoA carboxylase, beta subunit, putative; Identified by match to protein family HMM. (530 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (285 aa) |
| | CC_2140 | 5,10-methylenetetrahydrofolate reductase; Identified by match to TIGR protein family HMM TIGR00676; Belongs to the methylenetetrahydrofolate reductase family. (314 aa) |
| | CC_2137 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (899 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa) |
| | CC_2110 | Acetyltransferase, GNAT family; Identified by match to protein family HMM. (144 aa) |
| | IlvH | Acetolactate synthase, small subunit; Identified by match to TIGR protein family HMM TIGR00119. (185 aa) |
| | CC_2097 | Phosphoserine phosphatase; Identified by match to TIGR protein family HMM TIGR00338. (296 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (482 aa) |
| | CC_1975 | propionyl-CoA carboxylase, beta subunit; Identified by match to protein family HMM. (510 aa) |
| | fabZ | (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (159 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM; Belongs to the TrpC family. (262 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (341 aa) |
| | CC_1884 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | CC_1883 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (170 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa) |
| | CC_1805 | Smp-30/Cgr1 family protein; Similar to GB:AL009126; identified by sequence similarity; putative. (293 aa) |
| | lipA | Lipoic acid synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (325 aa) |
| | CC_1678 | 3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (426 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (78 aa) |
| | CC_1674 | Malonyl CoA-acyl carrier protein transacylase; Identified by match to TIGR protein family HMM TIGR00128. (314 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (364 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (252 aa) |
| | CC_1643 | Hydrolase, haloacid dehalogenase-like family; Identified by match to PFAM protein family HMM PF00702. (246 aa) |
| | phhA | Phenylalanine-4-hydroxylase; Identified by match to protein family HMM. (294 aa) |
| | CC_1605 | Peptidase, M20/M25/M40 family; Identified by match to protein family HMM. (414 aa) |
| | CC_1577 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by match to TIGR protein family HMM TIGR00508; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (400 aa) |
| | bioF | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (440 aa) |
| | bioD | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (219 aa) |
| | CC_1569 | NADP-dependent quinone oxidoreductase, putative; Identified by match to protein family HMM. (320 aa) |
| | acpS | Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (133 aa) |
| | CC_1551 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to PFAM protein family HMM PF01288. (177 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (524 aa) |
| | CC_1442 | 3-oxoacyl-(acyl-carrier-protein) synthase III, putative; Identified by match to protein family HMM. (392 aa) |
| | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase; Similar to SP:Q46225 PID:1359596; identified by sequence similarity; putative; Belongs to the KdsA family. (287 aa) |
| | CC_1426 | Cysteine synthase; Identified by match to protein family HMM. (332 aa) |
| | CC_1397 | Phospho-2-dehydro-3-deoxyheptonate aldolase, class I; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (369 aa) |
| | CC_1383 | Homoserine dehydrogenase; Identified by match to PFAM protein family HMM PF00742. (429 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (317 aa) |
| | fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (322 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (360 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (429 aa) |
| | CC_1224 | Gluconolactonase; Similar to SP:Q01578 GB:X67189 PID:48655; identified by sequence similarity; putative. (347 aa) |
| | folD | FolD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (344 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa) |
| | CC_1163 | Acyl carrier protein, putative; Identified by match to PFAM protein family HMM PF00550. (83 aa) |
| | CC_1162 | Aminotransferase, class II; Identified by match to protein family HMM. (404 aa) |
| | CC_1119 | Sulfite reductase (NADPH) hemoprotein beta-component; Identified by match to protein family HMM. (552 aa) |
| | CC_1116 | Chorismate mutase, putative; Identified by match to PFAM protein family HMM PF01817. (121 aa) |
| | CC_1092 | Acetyltransferase, GNAT family; Identified by match to protein family HMM. (181 aa) |
| | CC_1071 | Histidinol-phosphate aminotransferase, putative; Identified by match to protein family HMM. (409 aa) |
| | CC_0865 | Hypothetical protein; Identified by Glimmer2; putative. (399 aa) |
| | CC_0843 | Aspartokinase; Identified by match to TIGR protein family HMM TIGR00656; Belongs to the aspartokinase family. (415 aa) |
| | CC_0820 | Smp-30/Cgr1 family protein; Similar to GB:AL009126; identified by sequence similarity; putative. (289 aa) |
| | CC_0804 | Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1029 aa) |
| | CC_0736 | M20/M25/M40 family peptidase; Identified by match to protein family HMM. (471 aa) |
| | argD1 | Succinylornithine transaminase, putative; Identified by match to protein family HMM; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (392 aa) |
| | metXA | Homoserine O-acetyltransferase, putative; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (382 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (260 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (777 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (139 aa) |
| | CC_0416 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (115 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (377 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (304 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Identified by match to protein family HMM; Belongs to the transferase hexapeptide repeat family. (283 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (386 aa) |
| | CC_0261 | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (290 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (342 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (479 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (202 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (350 aa) |
| | CC_0191 | Acetyltransferase, GNAT family; Identified by match to protein family HMM. (179 aa) |
| | argG | Argininosuccinate synthase; Identified by match to TIGR protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (408 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (285 aa) |
