(23 nodes) Tryptophan metabolism network (Caulobacter vibrioides CB15)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	CC_0076	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725. (709 aa)
	CC_0077	Fatty oxidation complex, beta subunit, putative; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
	CC_0265	Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (412 aa)
	CC_0340	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (402 aa)
	CC_0342	2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by match to protein family HMM. (475 aa)
	CC_0353	Identified by match to PFAM protein family HMM PF00378. (286 aa)
	CC_0419	Aldehyde dehydrogenase; Identified by match to protein family HMM. (479 aa)
	CC_0510	acetyl-CoA acetyltransferase; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	CC_0779	Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
	CC_0894	acetyl-CoA acetyltransferase; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
	CC_1216	Aldehyde dehydrogenase; Identified by match to protein family HMM; Belongs to the aldehyde dehydrogenase family. (507 aa)
	CC_1352	Identified by match to PFAM protein family HMM PF00378. (350 aa)
	CC_1432	Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
	CC_1723	Identified by match to PFAM protein family HMM PF00378. (256 aa)
	CC_1731	Pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase; Identified by match to protein family HMM. (466 aa)
	CC_1814	Identified by match to PFAM protein family HMM PF00378. (275 aa)
	CC_1967	Conserved hypothetical protein; Identified by Glimmer2; putative. (512 aa)
	CC_2473	Identified by match to PFAM protein family HMM PF01425. (497 aa)
	CC_2793	Amine oxidase, flavin-containing; Identified by match to PFAM protein family HMM PF01593. (541 aa)
	kynA	Conserved hypothetical protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (263 aa)
	katG	Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity (By similarity). Important for stationary phase survival; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (737 aa)
	CC_3111	Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
	CC_3462	Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)

Your Current Organism:

Caulobacter vibrioides CB15

NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
CC_0076	CC_0077	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	Fatty oxidation complex, beta subunit, putative; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	0.999
CC_0076	CC_0265	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	0.998
CC_0076	CC_0353	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	Identified by match to PFAM protein family HMM PF00378.	0.951
CC_0076	CC_0419	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	Aldehyde dehydrogenase; Identified by match to protein family HMM.	0.918
CC_0076	CC_0510	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	acetyl-CoA acetyltransferase; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	0.996
CC_0076	CC_0779	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	0.996
CC_0076	CC_0894	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	acetyl-CoA acetyltransferase; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	0.996
CC_0076	CC_1216	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	Aldehyde dehydrogenase; Identified by match to protein family HMM; Belongs to the aldehyde dehydrogenase family.	0.919
CC_0076	CC_1352	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	Identified by match to PFAM protein family HMM PF00378.	0.925
CC_0076	CC_1432	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	0.995
CC_0076	CC_1723	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	Identified by match to PFAM protein family HMM PF00378.	0.928
CC_0076	CC_1814	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	Identified by match to PFAM protein family HMM PF00378.	0.948
CC_0076	CC_1967	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	Conserved hypothetical protein; Identified by Glimmer2; putative.	0.995
CC_0076	CC_3111	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	0.996
CC_0076	CC_3462	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	0.996
CC_0077	CC_0076	Fatty oxidation complex, beta subunit, putative; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.	0.999
CC_0077	CC_0265	Fatty oxidation complex, beta subunit, putative; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	0.907
CC_0077	CC_0340	Fatty oxidation complex, beta subunit, putative; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.816
CC_0077	CC_0353	Fatty oxidation complex, beta subunit, putative; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	Identified by match to PFAM protein family HMM PF00378.	0.600
CC_0077	CC_0510	Fatty oxidation complex, beta subunit, putative; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA acetyltransferase; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.	0.914