(5 nodes) Novobiocin biosynthesis network (Caulobacter vibrioides CB15)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CC_1071	Histidinol-phosphate aminotransferase, putative; Identified by match to protein family HMM. (409 aa)
	CC_1534	Aspartate aminotransferase; Identified by match to protein family HMM. (400 aa)
	hisC1	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (359 aa)
	CC_2224	Cyclohexadienyl dehydrogenase; Identified by match to PFAM protein family HMM PF02153. (312 aa)
	hisC2	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (378 aa)

Your Current Organism:

Caulobacter vibrioides CB15

NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CC_1071	CC_1534	CC_1071	CC_1534	Histidinol-phosphate aminotransferase, putative; Identified by match to protein family HMM.	Aspartate aminotransferase; Identified by match to protein family HMM.	0.818
CC_1071	CC_2224	CC_1071	CC_2224	Histidinol-phosphate aminotransferase, putative; Identified by match to protein family HMM.	Cyclohexadienyl dehydrogenase; Identified by match to PFAM protein family HMM PF02153.	0.966
CC_1071	hisC1	CC_1071	CC_2223	Histidinol-phosphate aminotransferase, putative; Identified by match to protein family HMM.	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.928
CC_1071	hisC2	CC_1071	CC_2534	Histidinol-phosphate aminotransferase, putative; Identified by match to protein family HMM.	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.927
CC_1534	CC_1071	CC_1534	CC_1071	Aspartate aminotransferase; Identified by match to protein family HMM.	Histidinol-phosphate aminotransferase, putative; Identified by match to protein family HMM.	0.818
CC_1534	CC_2224	CC_1534	CC_2224	Aspartate aminotransferase; Identified by match to protein family HMM.	Cyclohexadienyl dehydrogenase; Identified by match to PFAM protein family HMM PF02153.	0.910
CC_1534	hisC1	CC_1534	CC_2223	Aspartate aminotransferase; Identified by match to protein family HMM.	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.843
CC_1534	hisC2	CC_1534	CC_2534	Aspartate aminotransferase; Identified by match to protein family HMM.	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.834
CC_2224	CC_1071	CC_2224	CC_1071	Cyclohexadienyl dehydrogenase; Identified by match to PFAM protein family HMM PF02153.	Histidinol-phosphate aminotransferase, putative; Identified by match to protein family HMM.	0.966
CC_2224	CC_1534	CC_2224	CC_1534	Cyclohexadienyl dehydrogenase; Identified by match to PFAM protein family HMM PF02153.	Aspartate aminotransferase; Identified by match to protein family HMM.	0.910
CC_2224	hisC1	CC_2224	CC_2223	Cyclohexadienyl dehydrogenase; Identified by match to PFAM protein family HMM PF02153.	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.994
CC_2224	hisC2	CC_2224	CC_2534	Cyclohexadienyl dehydrogenase; Identified by match to PFAM protein family HMM PF02153.	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.972
hisC1	CC_1071	CC_2223	CC_1071	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	Histidinol-phosphate aminotransferase, putative; Identified by match to protein family HMM.	0.928
hisC1	CC_1534	CC_2223	CC_1534	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	Aspartate aminotransferase; Identified by match to protein family HMM.	0.843
hisC1	CC_2224	CC_2223	CC_2224	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	Cyclohexadienyl dehydrogenase; Identified by match to PFAM protein family HMM PF02153.	0.994
hisC1	hisC2	CC_2223	CC_2534	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.921
hisC2	CC_1071	CC_2534	CC_1071	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	Histidinol-phosphate aminotransferase, putative; Identified by match to protein family HMM.	0.927
hisC2	CC_1534	CC_2534	CC_1534	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	Aspartate aminotransferase; Identified by match to protein family HMM.	0.834
hisC2	CC_2224	CC_2534	CC_2224	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	Cyclohexadienyl dehydrogenase; Identified by match to PFAM protein family HMM PF02153.	0.972
hisC2	hisC1	CC_2534	CC_2223	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.921