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| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (285 aa) |
| | CC_0024 | Siroheme synthase-related protein; Similar to SP:P11098 GB:X14202 PID:581142 PID:606302 GB:U00096; identified by sequence similarity; putative. (282 aa) |
| | CC_0050 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. (407 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase (NAD+); Identified by match to PFAM protein family HMM PF01210; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (331 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (322 aa) |
| | CC_0076 | Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725. (709 aa) |
| | CC_0077 | Fatty oxidation complex, beta subunit, putative; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa) |
| | CC_0079 | acyl-CoA dehydrogenase, long-chain specific; Identified by match to PFAM protein family HMM PF00441. (391 aa) |
| | CC_0085 | Phosphoglucomutase; Identified by match to protein family HMM. (545 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Identified by match to TIGR protein family HMM TIGR00355. (529 aa) |
| | CC_0097 | Identified by match to PFAM protein family HMM PF01112. (292 aa) |
| | CC_0101 | Ribulose-phosphate 3-epimerase; Identified by match to PFAM protein family HMM PF00834; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa) |
| | CC_0107 | 2-octaprenyl-6-methoxyphenol hydroxylase; Identified by match to PFAM protein family HMM PF01360. (409 aa) |
| | argG | Argininosuccinate synthase; Identified by match to TIGR protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (408 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (350 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (202 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (479 aa) |
| | pgi | Glucose-6-phosphate isomerase; Identified by match to protein family HMM. (539 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (342 aa) |
| | CC_0261 | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (290 aa) |
| | CC_0265 | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (412 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (304 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Identified by match to PFAM protein family HMM PF01071. (427 aa) |
| | CC_0308 | Identified by match to PFAM protein family HMM PF00459. (259 aa) |
| | CC_0313 | Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UbiD family. (509 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (377 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (399 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa) |
| | Kgd | 2-oxoglutarate dehydrogenase, E1 component; Identified by match to TIGR protein family HMM TIGR00239. (976 aa) |
| | CC_0340 | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (402 aa) |
| | CC_0342 | 2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by match to protein family HMM. (475 aa) |
| | CC_0353 | Identified by match to PFAM protein family HMM PF00378. (286 aa) |
| | CC_0360 | Ornithine decarboxylase, putative; Identified by match to protein family HMM; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (419 aa) |
| | CC_0393 | Thiamine-pyrophosphate-requiring enzyme; Identified by match to protein family HMM. (512 aa) |
| | CC_0419 | Aldehyde dehydrogenase; Identified by match to protein family HMM. (479 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (139 aa) |
| | CC_0467 | 3-hydroxy-3-methylglutarate-CoA lyase; Identified by match to protein family HMM. (299 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (777 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (312 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (260 aa) |
| | hemF | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (290 aa) |
| | CC_0510 | acetyl-CoA acetyltransferase; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | metXA | Homoserine O-acetyltransferase, putative; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (382 aa) |
| | CC_0576 | Identified by match to PFAM protein family HMM PF01112. (294 aa) |
| | argD1 | Succinylornithine transaminase, putative; Identified by match to protein family HMM; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (392 aa) |
| | CC_0618 | Siroheme synthase; Identified by match to PFAM protein family HMM PF00590. (261 aa) |
| | CC_0690 | Identified by match to PFAM protein family HMM PF00441. (435 aa) |
| | CC_0703 | Riboflavin biosynthesis protein RibF; Identified by match to TIGR protein family HMM TIGR00083; Belongs to the ribF family. (313 aa) |
| | CC_0779 | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa) |
| | CC_0787 | Tryptophan halogenase, putative; Similar to GP:5669511; identified by sequence similarity; putative. (504 aa) |
| | CC_0791 | Trp repressor binding protein; Identified by match to protein family HMM. (199 aa) |
| | CC_0796 | Alpha-glucosidase, putative; Similar to PID:1519526; identified by sequence similarity; putative. (670 aa) |
| | CC_0797 | 1,4-beta-D-glucan glucohydrolase D; Identified by match to protein family HMM. (823 aa) |
| | CC_0804 | Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1029 aa) |
| | ubiG | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (252 aa) |
| | CC_0843 | Aspartokinase; Identified by match to TIGR protein family HMM TIGR00656; Belongs to the aspartokinase family. (415 aa) |
| | ispG | gcpE protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (383 aa) |
| | CC_0885 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (331 aa) |
| | CC_0886 | Riboflavin synthase, alpha subunit; Identified by match to TIGR protein family HMM TIGR00187. (205 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. (400 aa) |
| | ribH1 | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (153 aa) |
| | CC_0894 | acetyl-CoA acetyltransferase; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa) |
| | CC_0968 | beta-D-glucosidase; Identified by match to protein family HMM. (758 aa) |
| | CC_0971 | Tryptophan halogenase, putative; Identified by match to protein family HMM. (510 aa) |
| | CC_0972 | Tryptophan halogenase, putative; Identified by match to protein family HMM. (516 aa) |
| | CC_1002 | Tryptophan halogenase, putative; Similar to GP:5669511; identified by sequence similarity; putative. (499 aa) |
| | CC_1071 | Histidinol-phosphate aminotransferase, putative; Identified by match to protein family HMM. (409 aa) |
| | CC_1105 | Periplasmic beta-glucosidase; Identified by match to protein family HMM; Belongs to the glycosyl hydrolase 3 family. (743 aa) |
| | CC_1110 | Identified by match to PFAM protein family HMM PF00441. (387 aa) |
| | CC_1116 | Chorismate mutase, putative; Identified by match to PFAM protein family HMM PF01817. (121 aa) |
| | CC_1118 | Sirohaem synthase; Identified by match to PFAM protein family HMM PF00590. (307 aa) |
| | CC_1134 | Fructokinase; Identified by match to protein family HMM. (302 aa) |
| | CC_1140 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (300 aa) |
| | CC_1141 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (289 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa) |
| | CC_1205 | Transketolase family protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (784 aa) |
| | CC_1216 | Aldehyde dehydrogenase; Identified by match to protein family HMM; Belongs to the aldehyde dehydrogenase family. (507 aa) |
| | CC_1224 | Gluconolactonase; Similar to SP:Q01578 GB:X67189 PID:48655; identified by sequence similarity; putative. (347 aa) |
| | adk | Adenylate kinase, putative; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (191 aa) |
| | CC_1296 | Myo-inositol 2-dehydrogenase; Identified by match to protein family HMM. (328 aa) |
| | ispE | Kinase, GHMP family, group 2; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (295 aa) |
| | CC_1347 | Delta-aminolevulinic acid dehydratase; Identified by match to PFAM protein family HMM PF00490; Belongs to the ALAD family. (334 aa) |
| | CC_1352 | Identified by match to PFAM protein family HMM PF00378. (350 aa) |
| | CC_1355 | 5-aminolevulinic acid synthase; Identified by match to protein family HMM. (408 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (429 aa) |
| | ribH2 | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (154 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (360 aa) |
| | ctaA | Cytochrome c oxidase assembly protein, putative; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. (343 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (317 aa) |
| | CC_1383 | Homoserine dehydrogenase; Identified by match to PFAM protein family HMM PF00742. (429 aa) |
| | GlpX | glpX protein; Identified by match to TIGR protein family HMM TIGR00330. (317 aa) |
| | fbp | Fructose-1,6-bisphosphatase; Identified by match to protein family HMM. (336 aa) |
| | CC_1397 | Phospho-2-dehydro-3-deoxyheptonate aldolase, class I; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (369 aa) |
| | CC_1411 | Oxygen-independent coproporphyrinogen III oxidase; Identified by match to TIGR protein family HMM TIGR00538; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (454 aa) |
| | CC_1418 | Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (378 aa) |
| | CC_1421 | Dehydratase, IlvD/Edd family; Identified by match to PFAM protein family HMM PF00920; Belongs to the IlvD/Edd family. (600 aa) |
| | CC_1424 | Cystathionine beta-lyase; Identified by match to PFAM protein family HMM PF01053. (386 aa) |
| | CC_1426 | Cysteine synthase; Identified by match to protein family HMM. (332 aa) |
| | CC_1432 | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa) |
| | CC_1471 | Pyruvate phosphate dikinase; Identified by match to protein family HMM; Belongs to the PEP-utilizing enzyme family. (900 aa) |
| | cysC | Sulfate adenylate transferase, subunit 1/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (635 aa) |
| | cysD | Sulfate adenylate transferase, subunit 2; Identified by match to PFAM protein family HMM PF01507. (311 aa) |
| | CC_1529 | Tryptophan halogenase, putative; Identified by match to protein family HMM. (503 aa) |
| | CC_1534 | Aspartate aminotransferase; Identified by match to protein family HMM. (400 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (524 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (487 aa) |
| | CC_1643 | Hydrolase, haloacid dehalogenase-like family; Identified by match to PFAM protein family HMM PF00702. (246 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (252 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (500 aa) |
| | CC_1674 | Malonyl CoA-acyl carrier protein transacylase; Identified by match to TIGR protein family HMM TIGR00128. (314 aa) |
| | CC_1675 | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (78 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (193 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to PFAM protein family HMM PF00586. (341 aa) |
| | CC_1723 | Identified by match to PFAM protein family HMM PF00378. (256 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa) |
| | pdhA | Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (343 aa) |
| | CC_1727 | Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (450 aa) |
| | CC_1729 | Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (428 aa) |
| | CC_1731 | Pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase; Identified by match to protein family HMM. (466 aa) |
| | ispDF | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (382 aa) |
| | CC_1755 | Tryptophan halogenase, putative; Identified by match to protein family HMM. (507 aa) |
| | CC_1756 | beta-D-glucosidase; Identified by match to protein family HMM. (762 aa) |
| | CC_1764 | Isocitrate lyase; Identified by match to protein family HMM. (539 aa) |
| | CC_1765 | Malate synthase; Identified by match to PFAM protein family HMM PF01274; Belongs to the malate synthase family. (525 aa) |
| | CC_1803 | 3-oxoacyl-(acyl-carrier-protein) reductase, putative; Identified by match to protein family HMM. (247 aa) |
| | CC_1814 | Identified by match to PFAM protein family HMM PF00378. (275 aa) |
| | CC_1856 | Identified by match to PFAM protein family HMM PF01553. (272 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa) |
| | CC_1883 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (170 aa) |
| | CC_1884 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (513 aa) |
| | CC_1897 | Glutamine amidotransferase, class I; Identified by match to protein family HMM. (198 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (341 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM; Belongs to the TrpC family. (262 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (470 aa) |
| | CC_1906 | Citrate synthase; Identified by match to protein family HMM; Belongs to the citrate synthase family. (426 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (399 aa) |
| | CC_1918 | Phosphatidate cytidylyltransferase; Identified by match to PFAM protein family HMM PF01148; Belongs to the CDS family. (275 aa) |
| | uppS | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (259 aa) |
| | CC_1967 | Conserved hypothetical protein; Identified by Glimmer2; putative. (512 aa) |
| | CC_1975 | propionyl-CoA carboxylase, beta subunit; Identified by match to protein family HMM. (510 aa) |
| | surE | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (263 aa) |
| | CC_2051 | Pyruvate kinase; Identified by match to protein family HMM; Belongs to the pyruvate kinase family. (476 aa) |
| | CC_2052 | 1,4-beta-D-glucan glucohydrolase D; Identified by match to protein family HMM. (821 aa) |
| | glk | Glucokinase; Identified by match to TIGR protein family HMM TIGR00749; Belongs to the bacterial glucokinase family. (331 aa) |
| | pgl | 6-phospho-glucono-lactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (232 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (473 aa) |
| | dxs | 1-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (640 aa) |
| | CC_2069 | Geranyltranstransferase; Identified by match to PFAM protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. (294 aa) |
| | CC_2082 | Identified by match to protein family HMM; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (353 aa) |
| | CC_2097 | Phosphoserine phosphatase; Identified by match to TIGR protein family HMM TIGR00338. (296 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (295 aa) |
| | CC_2100 | Acetolactate synthase, large subunit; Identified by match to TIGR protein family HMM TIGR00118. (582 aa) |
| | IlvH | Acetolactate synthase, small subunit; Identified by match to TIGR protein family HMM TIGR00119. (185 aa) |
| | fumC | Fumarate hydratase, class II, aerobic; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa) |
| | CC_2113 | Identified by match to PFAM protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. (338 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa) |
| | CC_2128 | Gluconolactonase, putative; Similar to SP:Q01578 GB:X67189 PID:48655; identified by sequence similarity; putative. (303 aa) |
| | CC_2136 | Beta-glucosidase; Identified by match to protein family HMM. (469 aa) |
| | CC_2137 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (899 aa) |
| | CC_2138 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Similar to SP:P37586 GB:X52093; identified by sequence similarity; putative. (358 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (285 aa) |
| | CC_2168 | acetyl/propionyl-CoA carboxylase, alpha subunit; Identified by match to PFAM protein family HMM PF00289. (654 aa) |
| | CC_2179 | propionyl-CoA carboxylase, alpha subunit; Identified by match to PFAM protein family HMM PF00289. (669 aa) |
| | coq7 | Coq7 family protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. (200 aa) |
| | argH | Argininosuccinate lyase; Identified by match to TIGR protein family HMM TIGR00838. (442 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa) |
| | CC_2214 | Hypoxanthine-guanine phosphoribosyltransferase; Identified by match to protein family HMM. (176 aa) |
| | CC_2219 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Identified by match to PFAM protein family HMM PF01553. (236 aa) |
| | hisC1 | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (359 aa) |
| | CC_2224 | Cyclohexadienyl dehydrogenase; Identified by match to PFAM protein family HMM PF02153. (312 aa) |
| | argF | Ornithine carbamoyltransferase, anabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (311 aa) |
| | argD2 | Acetylornithine aminotransferase; Identified by match to protein family HMM; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa) |
| | gpmA | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (237 aa) |
| | CC_2264 | Identified by match to protein family HMM. (498 aa) |
| | CC_2285 | Identified by match to protein family HMM. (526 aa) |
| | CC_2288 | Tryptophan halogenase, putative; Similar to GP:5669518; identified by sequence similarity; putative. (504 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (118 aa) |
| | CC_2300 | Phospho-2-dehydro-3-deoxyheptonate aldolase, class II; Identified by match to PFAM protein family HMM PF01474. (459 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (227 aa) |
| | gph | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (237 aa) |
| | CC_2328 | Identified by match to PFAM protein family HMM PF00441. (387 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (428 aa) |
| | CC_2401 | Identified by match to PFAM protein family HMM PF00378. (275 aa) |
| | plsY | Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (218 aa) |
| | CC_2487 | Adenylosuccinate lyase; Identified by match to protein family HMM; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (436 aa) |
| | purC1 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Identified by match to TIGR protein family HMM TIGR00081; Belongs to the SAICAR synthetase family. (252 aa) |
| | purS | Conserved hypothetical protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer [...] (79 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (220 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (739 aa) |
| | CC_2516 | Alcohol dehydrogenase, class III; Identified by match to protein family HMM; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa) |
| | CC_2522 | Isocitrate dehydrogenase, NADP-dependent; Identified by match to TIGR protein family HMM TIGR00127; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (403 aa) |
| | hisC2 | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (378 aa) |
| | CC_2651 | Serine acetyltransferase; Identified by match to protein family HMM. (279 aa) |
| | CC_2793 | Amine oxidase, flavin-containing; Identified by match to PFAM protein family HMM PF01593. (541 aa) |
| | CC_2805 | Tryptophan halogenase, putative; Similar to GP:5669518; identified by sequence similarity; putative. (502 aa) |
| | CC_2807 | Tryptophan halogenase, putative; Identified by match to protein family HMM. (509 aa) |
| | CC_2808 | Tryptophan halogenase, putative; Similar to GP:5669511; identified by sequence similarity; putative. (503 aa) |
| | CC_2836 | 3-oxoacyl-(acyl-carrier protein) reductase; Identified by match to protein family HMM. (245 aa) |
| | CC_2910 | Conserved hypothetical protein; Identified by Glimmer2; putative. (300 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (296 aa) |
| | CC_2933 | Prephenate dehydratase; Identified by match to PFAM protein family HMM PF00800. (283 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (200 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (370 aa) |
| | CC_3029 | Alcohol dehydrogenase class III; Identified by match to protein family HMM. (366 aa) |
| | CC_3031 | Phospholipase C; Similar to GB:M30223 SP:P15713 GB:M59304 PID:151496 PID:151498; identified by sequence similarity; putative. (686 aa) |
| | katG | Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity (By similarity). Important for stationary phase survival; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (737 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Identified by match to TIGR protein family HMM TIGR00110. (617 aa) |
| | argJ | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (403 aa) |
| | CC_3093 | Threonine aldolase, low-specificity; Similar to GP:2865134; identified by sequence similarity; putative. (343 aa) |
| | CC_3105 | Threonine dehydratase; Identified by match to protein family HMM. (325 aa) |
| | CC_3108 | L-serine dehydratase; Identified by match to TIGR protein family HMM TIGR00720; Belongs to the iron-sulfur dependent L-serine dehydratase family. (462 aa) |
| | CC_3111 | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa) |
| | CC_3139 | Glutamate-1-semialdehyde 2,1-aminomutase; Identified by match to protein family HMM; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (466 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (372 aa) |
| | CC_3167 | Identified by match to protein family HMM; Belongs to the bacterial glucokinase family. (315 aa) |
| | CC_3204 | Hydrolase, alpha/beta hydrolase fold family; Identified by match to protein family HMM; Belongs to the AB hydrolase superfamily. MetX family. (358 aa) |
| | CC_3215 | D-3-phosphoglycerate dehydrogenase; Identified by match to PFAM protein family HMM PF00389; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa) |
| | CC_3216 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (396 aa) |
| | purC2 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Identified by match to PFAM protein family HMM PF01259; Belongs to the SAICAR synthetase family. (320 aa) |
| | CC_3248 | Glyceraldehyde 3-phosphate dehydrogenase; Identified by match to protein family HMM; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | pgk | Phosphoglycerate kinase; Identified by match to protein family HMM; Belongs to the phosphoglycerate kinase family. (396 aa) |
| | CC_3250 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (363 aa) |
| | suhB | Extragenic suppressor protein SuhB; Identified by match to PFAM protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. (256 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (361 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa) |
| | CC_3290 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Identified by match to protein family HMM. (162 aa) |
| | CC_3323 | Conserved hypothetical protein; Identified by Glimmer2; putative. (281 aa) |
| | gcvPB | Glycine cleavage system P protein, subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (524 aa) |
| | gcvPA | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (121 aa) |
| | CC_3355 | Glycine cleavage system T protein; Identified by match to TIGR protein family HMM TIGR00528. (375 aa) |
| | ispH | LytB protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (319 aa) |
| | thrB | Homoserine kinase; Similar to GP:6647291; identified by sequence similarity; putative; Belongs to the pseudomonas-type ThrB family. (317 aa) |
| | CC_3370 | Conserved hypothetical protein; Identified by Glimmer2; putative. (218 aa) |
| | CC_3399 | Threonine synthase; Identified by match to TIGR protein family HMM TIGR00260. (465 aa) |
| | ctaB | Protoheme IX farnesyl transferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (333 aa) |
| | ubiA | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (328 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (413 aa) |
| | CC_3454 | Identified by match to PFAM protein family HMM PF00441. (435 aa) |
| | CC_3462 | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa) |
| | asd-2 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (348 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (320 aa) |
| | HisZ | Hypothetical protein; Identified by Glimmer2; putative. (386 aa) |
| | SdhB | Succinate dehydrogenase, iron-sulfur protein; Identified by match to protein family HMM; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (260 aa) |
| | SdhA | Succinate dehydrogenase, flavoprotein subunit; Identified by match to protein family HMM; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (596 aa) |
| | CC_3528 | Succinate dehydrogenase, hydrophobic membrane anchor protein, putative; Similar to GP:3273340; identified by sequence similarity; putative. (139 aa) |
| | CC_3529 | Succinate dehydrogenase, cytochrome b556 subunit; Identified by match to PFAM protein family HMM PF01127. (135 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (307 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (275 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (410 aa) |
| | trpF | N-(5'-phosphoribosyl)-anthranilate isomerase; Identified by match to protein family HMM; Belongs to the TrpF family. (219 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (257 aa) |
| | CC_3580 | Aldehyde dehydrogenase B; Identified by match to protein family HMM; Belongs to the aldehyde dehydrogenase family. (506 aa) |
| | acsA | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (647 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (443 aa) |
| | CC_3606 | Glutamate synthase, small subunit; Identified by match to protein family HMM. (481 aa) |
| | CC_3607 | Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645. (1508 aa) |
| | tal | Transaldolase family protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa) |
| | CC_3615 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (293 aa) |
| | CC_3618 | Mannose-1-phosphate guanylyltransferase; Identified by match to protein family HMM; Belongs to the mannose-6-phosphate isomerase type 2 family. (436 aa) |
| | CC_3620 | Identified by match to TIGR protein family HMM TIGR00232; Belongs to the transketolase family. (653 aa) |
| | CC_3625 | Cysteine synthase; Identified by match to protein family HMM. (328 aa) |
| | CC_3629 | dTDP-D-glucose-4,6-dehydratase; Identified by match to protein family HMM; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (356 aa) |
| | CC_3631 | Acetylornithine deacetylase; Identified by match to protein family HMM. (391 aa) |
| | CC_3633 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (185 aa) |
| | CC_3635 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (400 aa) |
| | CC_3637 | UTP--glucose-1-phosphate uridylyltransferase; Identified by match to protein family HMM. (291 aa) |
| | CC_3642 | Citrate synthase; Identified by match to protein family HMM; Belongs to the citrate synthase family. (361 aa) |
| | CC_3643 | Citrate synthase; Identified by match to protein family HMM. (388 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa) |
| | CC_3667 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (903 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (288 aa) |
| | ubiE | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (252 aa) |
| | CC_3717 | Enoyl-(acyl-carrier-protein) reductase; Identified by match to protein family HMM. (278 aa) |
| | CC_3722 | D-isomer specific 2-hydroxyacid dehydrogenases family protein; Identified by match to PFAM protein family HMM PF00389; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (344 aa) |
| | CC_3724 | Coenzyme A transferase, putative; Similar to GB:L21902 SP:P38946 PID:347071; identified by sequence similarity; putative. (514 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Identified by match to PFAM protein family HMM PF00475. (196 aa) |
| | hisH | Amidotransferase HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity). (213 aa) |
| | hisA | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to TIGR protein family HMM TIGR00007. (241 aa) |
| | hisF | hisF protein (cyclase); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). (260 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase; Identified by match to PFAM protein family HMM PF01503. (107 aa) |
| | CC_3761 | Conserved hypothetical protein; Identified by Glimmer2; putative. (154 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family. (347 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen III to yield coproporphyrinogen III. (351 aa) |
