(42 nodes) Histidine kinase/HSP90-like ATPase superfamily network (Jeongeupia sp. USM3)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AOX99954.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
	AOX99018.1	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
	AOX99027.1	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
	AOX99050.1	Hypothetical protein; Member of a two-component regulatory system. (452 aa)
	AOX99057.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1086 aa)
	AOX99062.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1101 aa)
	AOX99223.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (966 aa)
	AOX99339.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (688 aa)
	AOX99409.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (491 aa)
	AOX99416.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (914 aa)
	AOX99417.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (920 aa)
	AOX99952.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (562 aa)
	AOY01361.1	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
	AOY01411.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
	mutL	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (639 aa)
	AOY01654.1	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
	AOY01729.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
	AOY01758.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (767 aa)
	AOY01829.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (588 aa)
	AOY01916.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
	AOY01943.1	Sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (873 aa)
	AOY02020.1	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
	AOX99959.1	Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology. (616 aa)
	AOY00029.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (881 aa)
	AOY00059.1	Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
	htpG	Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. (635 aa)
	AOY00071.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
	AOY00139.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (870 aa)
	AOY00416.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (606 aa)
	AOY00549.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (705 aa)
	AOY02281.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (528 aa)
	AOY00789.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (349 aa)
	AOY00825.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (433 aa)
	AOY00856.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (607 aa)
	gyrB	DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (803 aa)
	parE	DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (657 aa)
	AOY00990.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (426 aa)
	AOY02324.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
	AOY01232.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1903 aa)
	AOY01261.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (654 aa)
	AOY01330.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (744 aa)
	AOY01358.1	Phosphate regulon sensor histidine kinase PhoR; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)

Your Current Organism:

Jeongeupia sp. USM3

NCBI taxonomy Id: 1906741
Other names: J. sp. USM3

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOX99018.1	AOX99027.1	BJP62_00245	BJP62_00295	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.919
AOX99018.1	AOX99057.1	BJP62_00245	BJP62_00470	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.802
AOX99018.1	AOX99062.1	BJP62_00245	BJP62_00500	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.801
AOX99018.1	AOX99223.1	BJP62_00245	BJP62_01395	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.401
AOX99018.1	AOX99416.1	BJP62_00245	BJP62_02450	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.801
AOX99018.1	AOX99952.1	BJP62_00245	BJP62_05445	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.403
AOX99018.1	AOY00029.1	BJP62_00245	BJP62_05950	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.629
AOX99018.1	AOY00059.1	BJP62_00245	BJP62_06110	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.484
AOX99018.1	AOY00856.1	BJP62_00245	BJP62_10655	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.588
AOX99018.1	AOY01330.1	BJP62_00245	BJP62_13240	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.405
AOX99018.1	AOY01758.1	BJP62_00245	BJP62_15610	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.520
AOX99027.1	AOX99018.1	BJP62_00295	BJP62_00245	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.919
AOX99027.1	AOX99057.1	BJP62_00295	BJP62_00470	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.801
AOX99027.1	AOX99062.1	BJP62_00295	BJP62_00500	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.798
AOX99027.1	AOX99223.1	BJP62_00295	BJP62_01395	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.482
AOX99027.1	AOX99416.1	BJP62_00295	BJP62_02450	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.803
AOX99027.1	AOX99952.1	BJP62_00295	BJP62_05445	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.620
AOX99027.1	AOX99954.1	BJP62_00295	BJP62_05455	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.625
AOX99027.1	AOY00029.1	BJP62_00295	BJP62_05950	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.453
AOX99027.1	AOY00059.1	BJP62_00295	BJP62_06110	Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.683