STRINGSTRING
CDZ74215.1 CDZ74215.1 CDZ74216.1 CDZ74216.1 CDZ74217.1 CDZ74217.1 CDZ74502.1 CDZ74502.1 CDZ74503.1 CDZ74503.1 CDZ74504.1 CDZ74504.1 CDZ74531.1 CDZ74531.1 CDZ74532.1 CDZ74532.1 CDZ74533.1 CDZ74533.1 CDZ74534.1 CDZ74534.1 CDZ74535.1 CDZ74535.1 CDZ74536.1 CDZ74536.1 CDZ74537.1 CDZ74537.1 CDZ74538.1 CDZ74538.1 CDZ74540.1 CDZ74540.1 CDZ74541.1 CDZ74541.1 CDZ74571.1 CDZ74571.1 CDZ74572.1 CDZ74572.1 CDZ74667.1 CDZ74667.1 CDZ74668.1 CDZ74668.1 CDZ74669.1 CDZ74669.1 CDZ74727.1 CDZ74727.1 CDZ74728.1 CDZ74728.1 CDZ74729.1 CDZ74729.1 citF citF citE citE CDZ75178.1 CDZ75178.1 CDZ75179.1 CDZ75179.1 CDZ75180.1 CDZ75180.1 CDZ75181.1 CDZ75181.1 CDZ75182.1 CDZ75182.1 CDZ75192.1 CDZ75192.1 CDZ75193.1 CDZ75193.1 CDZ75194.1 CDZ75194.1 CDZ75195.2 CDZ75195.2 CDZ75196.1 CDZ75196.1 CDZ75197.1 CDZ75197.1 CDZ75198.2 CDZ75198.2 CDZ75199.2 CDZ75199.2 CDZ75200.1 CDZ75200.1 CDZ75201.1 CDZ75201.1 CDZ75202.1 CDZ75202.1 CDZ75203.1 CDZ75203.1 CDZ75204.1 CDZ75204.1 CDZ75345.1 CDZ75345.1 CDZ75346.1 CDZ75346.1 CDZ75347.1 CDZ75347.1 CDZ75406.1 CDZ75406.1 CDZ75407.1 CDZ75407.1 CDZ75408.2 CDZ75408.2 CDZ75409.1 CDZ75409.1 CDZ75411.1 CDZ75411.1 CDZ75412.1 CDZ75412.1 CDZ75413.1 CDZ75413.1 CDZ75414.1 CDZ75414.1 CDZ75415.1 CDZ75415.1 CDZ75491.1 CDZ75491.1 CDZ75565.1 CDZ75565.1 CDZ75566.1 CDZ75566.1 CDZ75648.1 CDZ75648.1 CDZ75649.1 CDZ75649.1 CDZ75681.1 CDZ75681.1 CDZ75682.1 CDZ75682.1 CDZ75683.1 CDZ75683.1 CDZ75690.1 CDZ75690.1 CDZ75699.1 CDZ75699.1 CDZ75700.1 CDZ75700.1 CDZ75702.1 CDZ75702.1 CDZ75703.1 CDZ75703.1 CDZ75704.1 CDZ75704.1 CDZ75705.1 CDZ75705.1 CDZ75706.1 CDZ75706.1 CDZ75707.1 CDZ75707.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDZ74215.1TRAP-T (Tripartite ATP-independent Periplasmic Transporter) family proteins generally consist of three components, and these systems have so far been found in Gram-negative bacteria, Gram-postive bacteria and archaea. The best characterized example is the DctPQM system of Rhodobacter capsulatus, a C4 dicarboxylate (malate, fumarate, succinate) transporter; High confidence in function and specificity. (346 aa)
CDZ74216.1TRAP-T family tripartite ATP-independent periplasmic transporter, membrane protein; High confidence in function and specificity. (163 aa)
CDZ74217.1TRAP-T family tripartite ATP-independent periplasmic transporter, membrane protein; The tripartite ATP-independent periplasmic (TRAP) transport system is firmly established as a new type of extracytoplasmic solute receptor (ESR)-dependent uptake systems, unrelated to ABC transporters. In TRAP transport systems the driving force for solute accumulation is an electrochemical ion gradient and not ATP hydrolysis; High confidence in function and specificity. (423 aa)
CDZ74502.1Hypothetical protein; High confidence in function and specificity. (336 aa)
CDZ74503.1ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological import and export systems. ABC transporters are minimally constituted of two conserved regions: a highly conserved ATP binding cassette (ABC) and a less conserved transmembrane domain (TMD). These regions can be found on the same protein (mostly in eukaryotes and bacterial exporters) or on two different ones (mostly bacterial importers); Family membership. (259 aa)
CDZ74504.1ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain PF00664; Family membership. (189 aa)
CDZ74531.1This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolizm and development in Streptomyces coelico [...] (231 aa)
CDZ74532.1TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; High confidence in function and specificity. (340 aa)
CDZ74533.1Putative membrane protein. (156 aa)
CDZ74534.1TRAP dicarboxylate transporter; High confidence in function and specificity. (428 aa)
CDZ74535.1Nitrilases; This subgroup includes mammalian Nit1 and Nit2, the Nit1-like domain of the invertebrate NitFhit, and various uncharacterized bacterial and archaeal Nit-like proteins. Nit1 and Nit2 are candidate tumor suppressor proteins. In NitFhit, the Nit1-like domain is encoded as a fusion protein with the non-homologous tumor suppressor, fragile histidine triad (Fhit). Mammalian Nit1 and Fhit may affect distinct signal pathways, and both may participate in DNA damage-induced apoptosis. Nit1 is a negative regulator in T cells. Overexpression of Nit2 in HeLa cells leads to a suppression [...] (267 aa)
CDZ74536.1Members of this family are demethylmenaquinone methyltransferases that convert dimethylmenaquinone (DMK) to menaquinone (MK) in the final step of menaquinone biosynthesis. This region is also found at the C-terminus of the DlpA protein; High confidence in function and specificity. (222 aa)
CDZ74537.1Hypothetical protein. (92 aa)
CDZ74538.1Hypothetical protein. (123 aa)
CDZ74540.1TRAP transporter; Tripartite ATP-independent periplasmic transporters (TRAP transporters) are a large family of solute transporters found in bacteria and archaea, but not in eukaryotes, that appear to be specific for the uptake of organic acids. They are unique in that they utilize a substrate binding protein (SBP) in combination with a secondary transporter; High confidence in function and specificity. (681 aa)
CDZ74541.1TRAP transporter solute receptor; This family contains the NMT1 and THI5 proteins. These proteins are proposed to be required for the biosynthesis of the pyrimidine moiety of thiamine [1]. They are regulated by thiamine; High confidence in function and specificity. (333 aa)
CDZ74571.1TRAP transporter solute receptor; TRAP-type uncharacterized transport system, periplasmic component [General function prediction only]; Family membership. (349 aa)
CDZ74572.1TRAP transporter 4TM/12TM fusion protein; Tripartite ATP-independent periplasmic transporters (TRAP transporters) are a large family of solute transporters found in bacteria and archaea, but not in eukaryotes, that appear to be specific for the uptake of organic acids. They are unique in that they utilize a substrate binding protein (SBP) in combination with a secondary transporter; High confidence in function and specificity. (648 aa)
CDZ74667.1Hypothetical protein; High confidence in function and specificity. (340 aa)
CDZ74668.1LysR transcriptional regulator; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. (285 aa)
CDZ74669.1Hypothetical protein; Frameshift; Family membership. (719 aa)
CDZ74727.1Transcriptional regulator [Transcription]; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. (304 aa)
CDZ74728.1This family consists of fumarylacetoacetate (FAA) hydrolase, or fumarylacetoacetate hydrolase (FAH) and it also includes HHDD isomerase/OPET decarboxylase from E. coli strain W. FAA is the last enzyme in the tyrosine catabolic pathway, it hydrolyses fumarylacetoacetate into fumarate and acetoacetate which then join the citric acid cycle; High confidence in function and specificity. (299 aa)
CDZ74729.13-oxoacyl-[acyl-carrier-protein] reductase; Reaction catalysed, (3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) <=> 3-oxoacyl-[acyl-carrier-protein] + NADPH; High confidence in function and specificity. (263 aa)
citFIn citrate-utilising prokaryotes, citrate lyasecleaves intracellular citrate into acetate and oxaloacetate, and is organised as a functional complex consisting of alpha, beta, and gamma subunits. The gamma subunit serves as an acyl carrier protein (ACP), and has a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group; High confidence in function and specificity. (515 aa)
citEIn citrate-utilising prokaryotes, citrate lyasecleaves intracellular citrate into acetate and oxaloacetate, and is organised as a functional complex consisting of alpha, beta, and gamma subunits. The gamma subunit serves as an acyl carrier protein (ACP), and has a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group; High confidence in function and specificity; Belongs to the HpcH/HpaI aldolase family. (300 aa)
CDZ75178.1Citrate lyase, gamma subunit [Energy production and conversion]; Family membership. (93 aa)
CDZ75179.1Membrane protein; Family membership. (73 aa)
CDZ75180.1TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; High confidence in function and specificity. (456 aa)
CDZ75181.1Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction; High confidence in function and specificity. (589 aa)
CDZ75182.1LysR substrate binding domain; The structure of this domain is known and is; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. (302 aa)
CDZ75192.1TRAP-type uncharacterized transport system; High confidence in function and specificity. (647 aa)
CDZ75193.1Hypothetical protein; Family membership. (58 aa)
CDZ75194.1TRAP-type uncharacterized transport system; High confidence in function and specificity. (234 aa)
CDZ75195.2Hypothetical protein; High confidence in function and specificity; Belongs to the CoA-transferase III family. (400 aa)
CDZ75196.1Methylmalonyl-CoA carboxyltransferase 12S subunit; High confidence in function and specificity. (514 aa)
CDZ75197.1Hypothetical protein; The structure of this domain is known and is; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. (293 aa)
CDZ75198.2Hydantoin racemase; This family contains aspartate racemase, maleate isomerases, glutamate racemase, hydantoin racemase and arylmalonate decarboxylase; Family membership. (217 aa)
CDZ75199.2Amidase, hydantoinase/carbamoylase family; Hydantoinase and carbamoylasehydrolyse the amide bonds of compounds containing carbamoyl groups or hydantoin rings.Enzymes in this subfamily are key biocatalysts for the production of optically pure amino acids from dl-5-substituted hydantoins (SSH); High confidence in function and specificity. (393 aa)
CDZ75200.1Amidohydrolase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; High confidence in function and specificity. (468 aa)
CDZ75201.1Na+/proline symporter; Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro-and eukaryotic cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient. The SMF is generated by primary sodium pumps (e.g. sodium/potassium ATPases, sodium translocating respiratory chain complexes) or via the action of sodium/proton antiporters; Hypothetical protein; Belongs to the sodium:solute symporter (SSF) [...] (346 aa)
CDZ75202.1Putative membrane protein. (125 aa)
CDZ75203.1Putative membrane protein. (30 aa)
CDZ75204.1Hypothetical protein; The structure of this domain is known and is; Family membership; Belongs to the LysR transcriptional regulatory family. (299 aa)
CDZ75345.1TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; High confidence in function and specificity. (420 aa)
CDZ75346.1Hypothetical protein; Family membership. (182 aa)
CDZ75347.1PBP2_TRAP_Siap_TeaA_like; This subfamily includes the periplasmic-binding component of TRAP transport systems such as SiaP (a sialic acid binding virulence factor), TeaA (an ectoine binding protein), and an uncharacterized TM0322 from hyperthermophilic bacterium Thermotoga maritima. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process and a smaller [...] (341 aa)
CDZ75406.1Na/Pi-cotransporter family protein; Na+/phosphate symporter [Inorganic ion transport and metabolism]; High confidence in function and specificity. (532 aa)
CDZ75407.1Putative secreted protein. (294 aa)
CDZ75408.2Hypothetical protein; Family membership. (416 aa)
CDZ75409.1Hypothetical protein; Family membership. (364 aa)
CDZ75411.1Hypothetical protein; High confidence in function and specificity. (494 aa)
CDZ75412.1Hypothetical protein; Family membership. (155 aa)
CDZ75413.1Hypothetical protein; Family membership. (366 aa)
CDZ75414.1UPF0597 protein; High confidence in function and specificity; Belongs to the UPF0597 family. (418 aa)
CDZ75415.1Sigma-54 dependent transcriptional regulator; High confidence in function and specificity. (594 aa)
CDZ75491.1LYSR family transcriptional regulatory protein; The structure of this domain is known and is; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. (310 aa)
CDZ75565.1Hypothetical protein; High confidence in function and specificity. (300 aa)
CDZ75566.1Fe-hydrogenase large subunit family protein; Iron only hydrogenase large subunit, C-terminal domain (pfam02906); High confidence in function and specificity. (498 aa)
CDZ75648.1Hypothetical protein; Family membership. (83 aa)
CDZ75649.1Group II intron reverse transcriptase/maturase; Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron [...] (96 aa)
CDZ75681.1TRAP-type C4-dicarboxylate transport system; Tripartite ATP-independent periplasmic transporters (TRAP transporters) are a large family of solute transporters found in bacteria and archaea, but not in eukaryotes, that appear to be specific for the uptake of organic acids. They are unique in that they utilize a substrate binding protein (SBP) in combination with a secondary transporter; High confidence in function and specificity. (429 aa)
CDZ75682.1Hypothetical protein; Family membership. (163 aa)
CDZ75683.1PBP2_TRAP_DctP10; This subgroup includes TRAP transporter DctP10 and its similar proteins. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or [...] (347 aa)
CDZ75690.1LysR family transcriptional regulator; This group of sequences represents a number of related clades with numerous examples of members adjacent to operons for the degradation of 2-aminoethylphosphonate (AEP) in Pseudomonas, Ralstonia, Bordetella and Burkholderia species. These are transcriptional regulators of the LysR family which contain a helix-turn-helix (HTH) domain (pfam00126) and a periplasmic substrate-binding protein-like domain (pfam03466). [Regulatory functions, DNA interactions]; Family membership. (297 aa)
CDZ75699.1RNA polymerase sigma-54 factor; A sigma factor is a DNA-binding protein protein that binds to the DNA-directed RNA polymerase core to produce the holoenzyme capable of initiating transcription at specific sites. Different sigma factors act in vegetative growth, heat shock, extracytoplasmic functions (ECF), etc. This model represents the clade of sigma factors called sigma-54, or RpoN (unrelated to sigma 70-type factors such as RpoD/SigA). RpoN is responsible for enhancer-dependent transcription, and its presence characteristically is associated with varied panels of activators, most of [...] (438 aa)
CDZ75700.1Hypothetical protein; High confidence in function and specificity. (306 aa)
CDZ75702.1D-isomer specific 2-hydroxyacid dehydrogenase; This domain is inserted into the catalytic domain, the large dehydrogenase and D-lactate dehydrogenase families in SCOP. N-terminal portion of which is represented by family pfam00389; High confidence in function and specificity. (323 aa)
CDZ75703.1TRAP transporters; Tripartite ATP-independent periplasmic transporters are a large family of solute transporters found in bacteria and archaea, but not in eukaryotes, that appear to be specific for the uptake of organic acids. They are unique in that they utilize a substrate binding protein (SBP) in combination with a secondary transporter; High confidence in function and specificity. (422 aa)
CDZ75704.1TRAP transporters; Tripartite ATP-independent periplasmic transporters are a large family of solute transporters found in bacteria and archaea, but not in eukaryotes, that appear to be specific for the uptake of organic acids. They are unique in that they utilize a substrate binding protein (SBP) in combination with a secondary transporter; High confidence in function and specificity. (162 aa)
CDZ75705.1TRAP transporter; Tripartite ATP-independent periplasmic transporters (TRAP transporters) are a large family of solute transporters found in bacteria and archaea, but not in eukaryotes, that appear to be specific for the uptake of organic acids. They are unique in that they utilize a substrate binding protein (SBP) in combination with a secondary transporter; High confidence in function and specificity. (355 aa)
CDZ75706.1Hypothetical protein; High confidence in function and specificity. (134 aa)
CDZ75707.1Hypothetical protein; High confidence in function and specificity. (402 aa)
Your Current Organism:
Peptoniphilus sp. ING2D1G
NCBI taxonomy Id: 1912856
Other names: P. sp. ING2-D1G, Peptoniphilus sp. ING2-D1G
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