STRINGSTRING
ANS62277.1 ANS62277.1 ANS62475.1 ANS62475.1 ANS63059.1 ANS63059.1 ANS63190.1 ANS63190.1 ANS63199.1 ANS63199.1 ANS63272.1 ANS63272.1 ANS63423.1 ANS63423.1 pfkA pfkA ANS63795.1 ANS63795.1 ANS63796.1 ANS63796.1 ANS63876.1 ANS63876.1 ANS64133.1 ANS64133.1 ANS64455.1 ANS64455.1 tal tal zwf zwf ANS64458.1 ANS64458.1 pgl pgl pgi pgi tpiA tpiA pgk pgk ANS64466.1 ANS64466.1 ANS64554.1 ANS64554.1 pfp pfp ANS65259.1 ANS65259.1 ANS65531.1 ANS65531.1 ANS65532.1 ANS65532.1 ANS65533.1 ANS65533.1 ANS65652.1 ANS65652.1 eno eno prs prs ANS65852.1 ANS65852.1 ANS65853.1 ANS65853.1 ANS65854.1 ANS65854.1 ANS66093.1 ANS66093.1 gpmA gpmA ANS66499.1 ANS66499.1 ANS66821.1 ANS66821.1 ANS67658.1 ANS67658.1 ANS67665.1 ANS67665.1 ANS67924.1 ANS67924.1 ANS68038.1 ANS68038.1 pfkA-2 pfkA-2 ANS68478.1 ANS68478.1 rbsK-2 rbsK-2 ANS68705.1 ANS68705.1 ANS69058.1 ANS69058.1 ANS69139.1 ANS69139.1 ANS69284.1 ANS69284.1 pgi-2 pgi-2 zwf-2 zwf-2 tal-2 tal-2 ANS69289.1 ANS69289.1 ANS69563.1 ANS69563.1 eno-2 eno-2 ANS69884.1 ANS69884.1 ANS69910.1 ANS69910.1 ANS70124.1 ANS70124.1 ANS70174.1 ANS70174.1 ANS70288.1 ANS70288.1 ANS70297.1 ANS70297.1 eno-3 eno-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANS62277.1DeoR family transcriptional regulator. (254 aa)
ANS62475.1LmbR. (220 aa)
ANS63059.1Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (484 aa)
ANS63190.1Ribose-5-phosphate isomerase. (151 aa)
ANS63199.1Tagatose-bisphosphate aldolase. (292 aa)
ANS63272.1DeoR family transcriptional regulator. (256 aa)
ANS63423.1Putative secreted protein. (343 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
ANS63795.1Phosphoenolpyruvate-dependent sugar phosphotransferase. (149 aa)
ANS63796.1Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (556 aa)
ANS63876.1Putative ribulose-phosphate 3-epimerase. (194 aa)
ANS64133.1Gluconokinase. (185 aa)
ANS64455.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (695 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (372 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (469 aa)
ANS64458.1Hypothetical protein. (393 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (260 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (524 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (258 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (403 aa)
ANS64466.1Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
ANS64554.1Pyruvate kinase; Belongs to the pyruvate kinase family. (475 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
ANS65259.1Ribose-5-phosphate isomerase B. (159 aa)
ANS65531.1Phosphotransferase system IIB component. (77 aa)
ANS65532.1Phosphotransferase system IIC transmembrane component. (430 aa)
ANS65533.1PTS transmembrane component. (417 aa)
ANS65652.1Putative PTS mannose-specific enzyme IIBCA component. (645 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa)
ANS65852.1Fructose-specific permease. (694 aa)
ANS65853.11-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (315 aa)
ANS65854.1DeoR-family transcriptional regulator. (253 aa)
ANS66093.1Sugar kinase; Belongs to the carbohydrate kinase PfkB family. (309 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (253 aa)
ANS66499.16-phosphogluconate dehydrogenase-like protein. (291 aa)
ANS66821.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (343 aa)
ANS67658.1Fructose 1,6-bisphosphatase II. (344 aa)
ANS67665.1Polyphosphate glucokinase. (248 aa)
ANS67924.1Putative ribokinase protein. (316 aa)
ANS68038.1Pyruvate kinase; Belongs to the pyruvate kinase family. (476 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
ANS68478.1Phosphocarrier protein. (93 aa)
rbsK-2Sugar kinase (PfkB family); Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (323 aa)
ANS68705.1Hypothetical protein. (983 aa)
ANS69058.1Transaldolase. (437 aa)
ANS69139.1Transketolase. (615 aa)
ANS69284.16-phosphogluconate dehydrogenase. (296 aa)
pgi-2Glucose-6-phosphate isomerase; Belongs to the GPI family. (568 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (531 aa)
tal-2Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (378 aa)
ANS69289.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (691 aa)
ANS69563.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa)
eno-2Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (436 aa)
ANS69884.1Hypothetical protein. (430 aa)
ANS69910.1Putative ribose-phosphate pyrophosphokinase. (317 aa)
ANS70124.1Putative phosphoketolase. (824 aa)
ANS70174.1Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa)
ANS70288.1Phosphoglucomutase. (546 aa)
ANS70297.1Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (356 aa)
eno-3Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)
Your Current Organism:
Streptomyces lincolnensis
NCBI taxonomy Id: 1915
Other names: ATCC 25466, BCRC 11173, CBS 630.70, CBS 699.69, CCRC 11173, CCRC:11173, DSM 2013, DSM 40355, IFO 13054, ISP 5355, JCM 4287, JCM 4488, KCTC 9088, KCTC 9089, NBRC 13054, NCIMB 9413, NRRL 2936, NRRL-ISP 5355, S. lincolnensis, VKM Ac-727
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