(78 nodes) Mixed, incl. Starch and sucrose metabolism, and Phosphoglycolate phosphatase-like, domain 2 network (Streptomyces lincolnensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANS62514.1	Glycoside hydrolase family 43; Belongs to the glycosyl hydrolase 43 family. (339 aa)
	ANS62515.1	Hypothetical protein. (484 aa)
	ANS62516.1	Kinase. (294 aa)
	ANS62518.1	Amino acid permease-associated region. (475 aa)
	ANS62595.1	Glycosyl hydrolase family 32 protein; Belongs to the glycosyl hydrolase 32 family. (466 aa)
	ANS62643.1	Putative glycogen debranching enzyme; Belongs to the glycosyl hydrolase 13 family. (704 aa)
	glgE	Glycosidase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. (665 aa)
	ANS62647.1	Trehalose synthase. (578 aa)
	ANS62648.1	Putative pep2 protein. (453 aa)
	glgB	Putative 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (736 aa)
	ANS62782.1	Hypothetical protein. (590 aa)
	ANS62846.1	Alpha-glucosidase. (538 aa)
	ANS62847.1	Amylo-alpha-1,6-glucosidase. (689 aa)
	ANS63425.1	Transcription regulator AsnC. (169 aa)
	ANS63426.1	Hydrolase. (229 aa)
	ANS63453.1	Alpha amylase. (483 aa)
	ANS63454.1	Hypothetical protein. (903 aa)
	ANS63728.1	UTP:glucose-1-phosphate uridylyltransferase. (315 aa)
	ANS63801.1	Glycosyl hydrolase; Belongs to the glycosyl hydrolase 31 family. (788 aa)
	ANS63991.1	Heme peroxidase. (558 aa)
	ANS64478.1	Fructokinase. (303 aa)
	ANS64776.1	Isomerase. (119 aa)
	ANS64777.1	Magnesium or manganese-dependent protein phosphatase. (546 aa)
	ANS64778.1	Bi-functional protein (secreted alpha-amylase/dextrinase); Belongs to the glycosyl hydrolase 13 family. (1797 aa)
	ANS64780.1	Alpha-amylase. (461 aa)
	ANS64781.1	Alpha-glucosidase. (564 aa)
	ANS64785.1	Maltose operon transcriptional repressor. (354 aa)
	ANS64786.1	Integral membrane protein. (285 aa)
	ANS64912.1	Hydrolase. (219 aa)
	ANS65106.1	ROK-family transcriptional regulator. (400 aa)
	ANS65107.1	Hypothetical protein. (485 aa)
	ANS65108.1	Hypothetical protein. (645 aa)
	ANS65297.1	4-alpha-glucanotransferase. (701 aa)
	ANS66086.1	Glycosyl transferase family 2 protein. (314 aa)
	ANS66087.1	Trehalose-phosphate synthase. (453 aa)
	ANS66088.1	Trehalose-6-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. (290 aa)
	ANS66624.1	Sugar hydrolase. (552 aa)
	ANS66664.1	Glycoside hydrolase family protein. (666 aa)
	ANS67322.1	Phosphohexomutase/phosphatase. (234 aa)
	ANS67323.1	2-epi-5-epi-valiolone-7-phosphate 2-epimerase. (299 aa)
	ANS67324.1	Cyclitol oxidoreductase. (254 aa)
	ANS67325.1	Cyclitol dehydrogenase. (388 aa)
	ANS67326.1	2-epi-5-epi-valiolone-7-kinase. (359 aa)
	ANS67327.1	Putative secreted FAD-linked oxidase. (544 aa)
	ANS67328.1	2-epi-5-epi-valiolone synthase. (419 aa)
	glgB-2	Glycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (952 aa)
	ANS68084.1	Hypothetical protein. (465 aa)
	ANS68085.1	Trehalose synthase. (566 aa)
	glgE-2	Alpha-amylase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. (653 aa)
	ANS68088.1	Glycogen phosphorylase. (861 aa)
	ANS68101.1	Glycogen debranching enzyme; Belongs to the glycosyl hydrolase 13 family. (747 aa)
	ANS68778.1	Alpha-amylase. (581 aa)
	ANS68783.1	Alpha-amylase. (787 aa)
	ANS68784.1	Glycogen debranching enzyme; Belongs to the glycosyl hydrolase 13 family. (706 aa)
	ANS69059.1	HAD-superfamily hydrolase, subfamily IA, variant 3. (249 aa)
	ANS69531.1	Glutathione S-transferase. (288 aa)
	ANS69567.1	Glycosyl transferase. (374 aa)
	glgC	Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (406 aa)
	ANS69579.1	Alpha-mannosidase. (165 aa)
	ANS69580.1	Prolyl oligopeptidase family protein. (346 aa)
	ANS69581.1	Hypothetical protein. (381 aa)
	ANS69727.1	Phosphatase/phosphohexomutase-like protein. (138 aa)
	ANS69926.1	Hypothetical protein. (339 aa)
	ANS69927.1	Hypothetical protein. (323 aa)
	ANS70052.1	Hypothetical protein. (367 aa)
	ANS70053.1	Putative hydrolase. (246 aa)
	ANS70054.1	Hypothetical protein. (784 aa)
	ANS70055.1	Integral membrane protein. (499 aa)
	ANS70056.1	Hypothetical protein. (313 aa)
	ANS70058.1	High-affinity nickel-transport protein; Belongs to the NiCoT transporter (TC 2.A.52) family. (352 aa)
	ANS70059.1	Hypothetical protein. (94 aa)
	ANS70131.1	Hypothetical protein. (291 aa)
	ANS70132.1	Hypothetical protein. (259 aa)
	ANS70133.1	Hypothetical protein. (789 aa)
	ANS70326.1	Alpha-glucosidase. (630 aa)
	ANS70341.1	Fructokinase; Belongs to the carbohydrate kinase PfkB family. (328 aa)
	ANS70344.1	Levanase. (852 aa)
	ANS70350.1	Putative sucrose-6-phosphate hydrolase; Belongs to the glycosyl hydrolase 32 family. (490 aa)

Your Current Organism:

Streptomyces lincolnensis

NCBI taxonomy Id: 1915
Other names: ATCC 25466, BCRC 11173, CBS 630.70, CBS 699.69, CCRC 11173, CCRC:11173, DSM 2013, DSM 40355, IFO 13054, ISP 5355, JCM 4287, JCM 4488, KCTC 9088, KCTC 9089, NBRC 13054, NCIMB 9413, NRRL 2936, NRRL-ISP 5355, S. lincolnensis, VKM Ac-727

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANS62514.1	ANS62515.1	SLINC_0290	SLINC_0291	Glycoside hydrolase family 43; Belongs to the glycosyl hydrolase 43 family.	Hypothetical protein.	0.520
ANS62514.1	ANS62516.1	SLINC_0290	SLINC_0292	Glycoside hydrolase family 43; Belongs to the glycosyl hydrolase 43 family.	Kinase.	0.463
ANS62514.1	ANS66664.1	SLINC_0290	SLINC_4440	Glycoside hydrolase family 43; Belongs to the glycosyl hydrolase 43 family.	Glycoside hydrolase family protein.	0.448
ANS62514.1	ANS70326.1	SLINC_0290	SLINC_8102	Glycoside hydrolase family 43; Belongs to the glycosyl hydrolase 43 family.	Alpha-glucosidase.	0.466
ANS62515.1	ANS62514.1	SLINC_0291	SLINC_0290	Hypothetical protein.	Glycoside hydrolase family 43; Belongs to the glycosyl hydrolase 43 family.	0.520
ANS62515.1	ANS62516.1	SLINC_0291	SLINC_0292	Hypothetical protein.	Kinase.	0.678
ANS62516.1	ANS62514.1	SLINC_0292	SLINC_0290	Kinase.	Glycoside hydrolase family 43; Belongs to the glycosyl hydrolase 43 family.	0.463
ANS62516.1	ANS62515.1	SLINC_0292	SLINC_0291	Kinase.	Hypothetical protein.	0.678
ANS62518.1	ANS62647.1	SLINC_0294	SLINC_0423	Amino acid permease-associated region.	Trehalose synthase.	0.428
ANS62518.1	ANS62846.1	SLINC_0294	SLINC_0622	Amino acid permease-associated region.	Alpha-glucosidase.	0.428
ANS62518.1	ANS63453.1	SLINC_0294	SLINC_1229	Amino acid permease-associated region.	Alpha amylase.	0.428
ANS62518.1	ANS64778.1	SLINC_0294	SLINC_2554	Amino acid permease-associated region.	Bi-functional protein (secreted alpha-amylase/dextrinase); Belongs to the glycosyl hydrolase 13 family.	0.442
ANS62518.1	ANS64780.1	SLINC_0294	SLINC_2556	Amino acid permease-associated region.	Alpha-amylase.	0.428
ANS62518.1	ANS64781.1	SLINC_0294	SLINC_2557	Amino acid permease-associated region.	Alpha-glucosidase.	0.428
ANS62518.1	ANS66624.1	SLINC_0294	SLINC_4400	Amino acid permease-associated region.	Sugar hydrolase.	0.428
ANS62518.1	ANS68085.1	SLINC_0294	SLINC_5861	Amino acid permease-associated region.	Trehalose synthase.	0.428
ANS62518.1	glgE	SLINC_0294	SLINC_0422	Amino acid permease-associated region.	Glycosidase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.	0.428
ANS62518.1	glgE-2	SLINC_0294	SLINC_5862	Amino acid permease-associated region.	Alpha-amylase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.	0.428
ANS62595.1	ANS62846.1	SLINC_0371	SLINC_0622	Glycosyl hydrolase family 32 protein; Belongs to the glycosyl hydrolase 32 family.	Alpha-glucosidase.	0.933
ANS62595.1	ANS63801.1	SLINC_0371	SLINC_1577	Glycosyl hydrolase family 32 protein; Belongs to the glycosyl hydrolase 32 family.	Glycosyl hydrolase; Belongs to the glycosyl hydrolase 31 family.	0.913

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