STRINGSTRING
ANS69973.1 ANS69973.1 ANS69641.1 ANS69641.1 ANS69586.1 ANS69586.1 ANS69407.1 ANS69407.1 ANS69323.1 ANS69323.1 ANS69300.1 ANS69300.1 ANS69281.1 ANS69281.1 ANS69264.1 ANS69264.1 ANS69183.1 ANS69183.1 ANS69093.1 ANS69093.1 ANS68684.1 ANS68684.1 ANS68599.1 ANS68599.1 ANS68585.1 ANS68585.1 dapA-2 dapA-2 leuD leuD leuC leuC ANS67750.1 ANS67750.1 ANS69642.1 ANS69642.1 eno-2 eno-2 ANS70179.1 ANS70179.1 eno-3 eno-3 ANS70489.1 ANS70489.1 ANS67655.1 ANS67655.1 fumC fumC ANS67554.1 ANS67554.1 nnrE nnrE ANS67232.1 ANS67232.1 mqnA mqnA ANS67062.1 ANS67062.1 ANS67060.1 ANS67060.1 ilvD ilvD ANS66907.1 ANS66907.1 ANS66420.1 ANS66420.1 ANS65968.1 ANS65968.1 ANS65948.1 ANS65948.1 eno eno hutU hutU ANS65587.1 ANS65587.1 ANS65554.1 ANS65554.1 ANS65553.1 ANS65553.1 ANS65552.1 ANS65552.1 ANS65389.1 ANS65389.1 ANS65222.1 ANS65222.1 ANS65161.1 ANS65161.1 ANS65160.1 ANS65160.1 ANS65137.1 ANS65137.1 ANS65100.1 ANS65100.1 ANS64865.1 ANS64865.1 ANS64647.1 ANS64647.1 hisB hisB trpB trpB trpA trpA psuG psuG aroQ aroQ dapA dapA ANS64401.1 ANS64401.1 ANS64396.1 ANS64396.1 ANS64395.1 ANS64395.1 ectC ectC ANS64159.1 ANS64159.1 ANS63719.1 ANS63719.1 ANS63534.1 ANS63534.1 ANS63458.1 ANS63458.1 ANS63441.1 ANS63441.1 ANS63440.1 ANS63440.1 ANS63281.1 ANS63281.1 ANS63070.1 ANS63070.1 ANS63068.1 ANS63068.1 ANS62612.1 ANS62612.1 ANS62559.1 ANS62559.1 ANS62451.1 ANS62451.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANS69973.1Dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (325 aa)
ANS69641.15-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. (317 aa)
ANS69586.1Mandelate racemase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (474 aa)
ANS69407.1Enoyl coA hydratase. (249 aa)
ANS69323.1Dihydrodipicolinate synthase; Belongs to the DapA family. (298 aa)
ANS69300.1Dehydratase. (151 aa)
ANS69281.1Sugar phosphate isomerase/epimerase. (598 aa)
ANS69264.1Hypothetical protein. (132 aa)
ANS69183.1Pterin-4-alpha-carbinolamine dehydratase. (101 aa)
ANS69093.1Hypothetical protein. (170 aa)
ANS68684.1Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (192 aa)
ANS68599.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
ANS68585.1enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (275 aa)
dapA-2Dihydrodipicolinate synthase 1; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa)
leuD3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (476 aa)
ANS67750.12-cyclohexenylcarbonyl CoA isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (263 aa)
ANS69642.1Glucarate dehydratase. (98 aa)
eno-2Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (436 aa)
ANS70179.1Myosin-cross-reactive antigen. (527 aa)
eno-3Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)
ANS70489.1Prephenate dehydratase. (278 aa)
ANS67655.1Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (555 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (451 aa)
ANS67554.1Carbonic anhydrase. (251 aa)
nnrEHypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (501 aa)
ANS67232.1Hypothetical protein; Belongs to the UPF0336 family. (150 aa)
mqnAHypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (282 aa)
ANS67062.1Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (330 aa)
ANS67060.1uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase. (576 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (617 aa)
ANS66907.1Integral membrane transport protein. (760 aa)
ANS66420.1Prephenate dehydratase. (310 aa)
ANS65968.1enoyl-CoA hydratase. (266 aa)
ANS65948.1enoyl-CoA hydratase/isomerase. (257 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (554 aa)
ANS65587.1Hypothetical protein. (383 aa)
ANS65554.1Nitrile hydratase beta subunit. (98 aa)
ANS65553.1Nitrile hydratase beta subunit. (107 aa)
ANS65552.1Nitrile hydratase. (200 aa)
ANS65389.1Hypothetical protein. (384 aa)
ANS65222.1dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (323 aa)
ANS65161.1Glucarate dehydratase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (429 aa)
ANS65160.15-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. (312 aa)
ANS65137.1Dihydrodipicolinate synthase; Belongs to the DapA family. (311 aa)
ANS65100.1Carbonic anhydrase. (115 aa)
ANS64865.1UfaA2 protein. (285 aa)
ANS64647.1Carbonic anhydrase. (218 aa)
hisBImidazoleglycerol-phosphate dehydratase. (200 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (427 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (272 aa)
psuGHypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (302 aa)
aroQHypothetical protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (157 aa)
dapADihydrodipicolinate synthase 2; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (303 aa)
ANS64401.15-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. (313 aa)
ANS64396.1Dihydropicolinate synthase; Belongs to the DapA family. (302 aa)
ANS64395.1Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (578 aa)
ectCL-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (134 aa)
ANS64159.1Hypothetical protein. (137 aa)
ANS63719.1Putative siderophore binding protein. (195 aa)
ANS63534.1Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (578 aa)
ANS63458.1Uncharacterized protein ORF2 in instable DNA locus. (402 aa)
ANS63441.1Mandelate racemase/muconate lactonizing enzyme. (416 aa)
ANS63440.15-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. (297 aa)
ANS63281.1Glucarate dehydratase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (442 aa)
ANS63070.1Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (544 aa)
ANS63068.1Galactonate dehydratase. (47 aa)
ANS62612.1Acyl dehydratase. (154 aa)
ANS62559.1Carbonic anhydrase (carbonate dehydratase). (248 aa)
ANS62451.1Carbonic anhydrase. (190 aa)
Your Current Organism:
Streptomyces lincolnensis
NCBI taxonomy Id: 1915
Other names: ATCC 25466, BCRC 11173, CBS 630.70, CBS 699.69, CCRC 11173, CCRC:11173, DSM 2013, DSM 40355, IFO 13054, ISP 5355, JCM 4287, JCM 4488, KCTC 9088, KCTC 9089, NBRC 13054, NCIMB 9413, NRRL 2936, NRRL-ISP 5355, S. lincolnensis, VKM Ac-727
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