STRINGSTRING
ANS67563.1 ANS67563.1 kbl kbl ANS69813.1 ANS69813.1 ANS69846.1 ANS69846.1 ANS70003.1 ANS70003.1 ANS70029.1 ANS70029.1 ANS70383.1 ANS70383.1 glyA-4 glyA-4 ANS70543.1 ANS70543.1 kynU-2 kynU-2 ANS62464.1 ANS62464.1 ANS62704.1 ANS62704.1 ANS62969.1 ANS62969.1 ANS63106.1 ANS63106.1 ANS63116.1 ANS63116.1 ANS63170.1 ANS63170.1 ANS63468.1 ANS63468.1 ANS63549.1 ANS63549.1 ANS63609.1 ANS63609.1 ANS63634.1 ANS63634.1 ANS63655.1 ANS63655.1 bioA bioA gcvP gcvP ANS63832.1 ANS63832.1 argD argD ANS64348.1 ANS64348.1 ANS64357.1 ANS64357.1 ANS64441.1 ANS64441.1 ANS64558.1 ANS64558.1 hisC hisC ANS64634.1 ANS64634.1 ANS64712.1 ANS64712.1 ANS64981.1 ANS64981.1 ANS65429.1 ANS65429.1 ANS65714.1 ANS65714.1 serC serC ANS66085.1 ANS66085.1 pat pat ANS66453.1 ANS66453.1 ANS66475.1 ANS66475.1 ANS66626.1 ANS66626.1 ANS66648.1 ANS66648.1 ANS66815.1 ANS66815.1 kynU kynU ANS66850.1 ANS66850.1 ANS66972.1 ANS66972.1 ANS67064.1 ANS67064.1 hemL hemL ANS67239.1 ANS67239.1 ANS67331.1 ANS67331.1 ANS67355.1 ANS67355.1 glyA glyA ANS67567.1 ANS67567.1 ANS67590.1 ANS67590.1 ANS67742.1 ANS67742.1 lysA lysA ANS67969.1 ANS67969.1 glyA-2 glyA-2 ANS68088.1 ANS68088.1 ANS68112.1 ANS68112.1 glyA-3 glyA-3 ANS68141.1 ANS68141.1 ANS68298.1 ANS68298.1 ANS68320.1 ANS68320.1 ANS68433.1 ANS68433.1 ANS68570.1 ANS68570.1 ANS68645.1 ANS68645.1 ANS68978.1 ANS68978.1 ANS68993.1 ANS68993.1 ANS69040.1 ANS69040.1 ANS69166.1 ANS69166.1 ANS69275.1 ANS69275.1 ANS69430.1 ANS69430.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANS67563.1Cystathionine gamma-synthase. (384 aa)
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (397 aa)
ANS69813.1Aminotransferase class I and II. (394 aa)
ANS69846.1Threonine dehydratase. (325 aa)
ANS70003.1Diaminopimelate decarboxylase. (418 aa)
ANS70029.1Transferase. (392 aa)
ANS70383.1Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
glyA-4Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (425 aa)
ANS70543.1Aminotransferase, class I and II. (426 aa)
kynU-2Putative hydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (422 aa)
ANS62464.1LmbF. (427 aa)
ANS62704.1Threonine dehydratase. (322 aa)
ANS62969.1L-threonine synthase. (434 aa)
ANS63106.1Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
ANS63116.1Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
ANS63170.1Hypothetical protein. (275 aa)
ANS63468.1Putative aminotransferase. (400 aa)
ANS63549.1Orn/DAP/Arg decarboxylase 2. (492 aa)
ANS63609.1Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (412 aa)
ANS63634.1Putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
ANS63655.18-amino-7-oxononanoate synthase. (375 aa)
bioAAdenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (426 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa)
ANS63832.1GntR family regulatory protein. (502 aa)
argDAcetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (394 aa)
ANS64348.1Hypothetical protein. (361 aa)
ANS64357.1Diaminobutyrate-2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (423 aa)
ANS64441.1Aminotransferase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (418 aa)
ANS64558.1Amino acid decarboxylase. (493 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (371 aa)
ANS64634.1Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (239 aa)
ANS64712.1Aminotransferase; Belongs to the sulfur carrier protein TusA family. (416 aa)
ANS64981.1Aminotransferase. (576 aa)
ANS65429.1Pyridoxal-dependent decarboxylase. (488 aa)
ANS65714.1Lysine/ornithine decarboxylase. (464 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (372 aa)
ANS66085.1Threonine synthase. (428 aa)
patAminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa)
ANS66453.1Cystathionine gamma-lyase. (384 aa)
ANS66475.1Hypothetical protein. (343 aa)
ANS66626.1Hypothetical protein. (276 aa)
ANS66648.1Hypothetical protein. (233 aa)
ANS66815.1Aminotransferase. (397 aa)
kynUHydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (406 aa)
ANS66850.1Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (451 aa)
ANS66972.1Glutamate decarboxylase; Belongs to the group II decarboxylase family. (470 aa)
ANS67064.1Aminotransferase. (401 aa)
hemLGlutamate-1-semialdehyde aminotransferase. (439 aa)
ANS67239.1Aspartate aminotransferase. (408 aa)
ANS67331.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (393 aa)
ANS67355.1Hypothetical protein. (217 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (483 aa)
ANS67567.1Amino acid deaminase. (409 aa)
ANS67590.1Aminotransferase AlaT. (403 aa)
ANS67742.1N-succinyldiaminopimelate aminotransferase. (363 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (463 aa)
ANS67969.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (352 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa)
ANS68088.1Glycogen phosphorylase. (861 aa)
ANS68112.1Hypothetical protein. (180 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa)
ANS68141.1Pyridoxal-phosphate-dependent aminotransferase. (387 aa)
ANS68298.1Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (454 aa)
ANS68320.14-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
ANS68433.1Class III aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (343 aa)
ANS68570.15-aminolevulinate synthase. (398 aa)
ANS68645.1Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
ANS68978.1Aminotransferase AlaT. (402 aa)
ANS68993.1Hypothetical protein. (175 aa)
ANS69040.1Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (428 aa)
ANS69166.1Hypothetical protein. (416 aa)
ANS69275.1Hypothetical protein. (158 aa)
ANS69430.1Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (472 aa)
Your Current Organism:
Streptomyces lincolnensis
NCBI taxonomy Id: 1915
Other names: ATCC 25466, BCRC 11173, CBS 630.70, CBS 699.69, CCRC 11173, CCRC:11173, DSM 2013, DSM 40355, IFO 13054, ISP 5355, JCM 4287, JCM 4488, KCTC 9088, KCTC 9089, NBRC 13054, NCIMB 9413, NRRL 2936, NRRL-ISP 5355, S. lincolnensis, VKM Ac-727
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