STRINGSTRING
ANS64329.1 ANS64329.1 ANS62538.1 ANS62538.1 melC1 melC1 melC2 melC2 ANS62747.1 ANS62747.1 pdxT pdxT pdxS pdxS ANS63952.1 ANS63952.1 thiE thiE ANS64665.1 ANS64665.1 thiG thiG ANS65059.1 ANS65059.1 ANS65124.1 ANS65124.1 ANS65233.1 ANS65233.1 ANS65341.1 ANS65341.1 ANS65513.1 ANS65513.1 ANS65960.1 ANS65960.1 pdxH pdxH serC serC thiC thiC ANS66479.1 ANS66479.1 ANS66885.1 ANS66885.1 folE folE pckG pckG ANS67637.1 ANS67637.1 thiL thiL ANS68229.1 ANS68229.1 ANS68534.1 ANS68534.1 dxs dxs ANS69183.1 ANS69183.1 ANS69225.1 ANS69225.1 ANS69281.1 ANS69281.1 slp slp dxs-2 dxs-2 ANS69807.1 ANS69807.1 ANS70051.1 ANS70051.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANS64329.1Glyoxalase family protein. (137 aa)
ANS62538.1Hypothetical protein. (138 aa)
melC1Tyrosinase cofactor; This protein may function to deliver copper to tyrosinase; Belongs to the melC1 family. (140 aa)
melC2Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds; Belongs to the tyrosinase family. (274 aa)
ANS62747.1Hypothetical protein. (130 aa)
pdxTGlutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (206 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (303 aa)
ANS63952.1Regulator. (137 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (226 aa)
ANS64665.1Sulfur transfer protein involved in thiamine biosynthesis. (72 aa)
thiGThiazole biosynthesis protein thiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (264 aa)
ANS65059.1NMT1/THI5 like domain protein. (380 aa)
ANS65124.1Undecaprenyl phosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (277 aa)
ANS65233.1Non-specific serine/threonine protein kinase. (374 aa)
ANS65341.1Tyrosinase co-factor. (158 aa)
ANS65513.1Glyoxalase family protein. (120 aa)
ANS65960.1Oxidase. (221 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (226 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (372 aa)
thiCThiamine biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (600 aa)
ANS66479.11L-myo-inositol-1-phosphate synthase. (360 aa)
ANS66885.1Hypothetical protein. (135 aa)
folEGTP cyclohydrolase I. (201 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa)
ANS67637.1Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (257 aa)
thiLThiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (322 aa)
ANS68229.1Putative phosphomethylpyrimidine kinase. (266 aa)
ANS68534.1Tyrosinase. (358 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (642 aa)
ANS69183.1Pterin-4-alpha-carbinolamine dehydratase. (101 aa)
ANS69225.1Secreted protein. (400 aa)
ANS69281.1Sugar phosphate isomerase/epimerase. (598 aa)
slpPhosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (226 aa)
dxs-21-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (632 aa)
ANS69807.1Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (595 aa)
ANS70051.1Glyoxalase/bleomycin resistance protein/dioxygenase. (165 aa)
Your Current Organism:
Streptomyces lincolnensis
NCBI taxonomy Id: 1915
Other names: ATCC 25466, BCRC 11173, CBS 630.70, CBS 699.69, CCRC 11173, CCRC:11173, DSM 2013, DSM 40355, IFO 13054, ISP 5355, JCM 4287, JCM 4488, KCTC 9088, KCTC 9089, NBRC 13054, NCIMB 9413, NRRL 2936, NRRL-ISP 5355, S. lincolnensis, VKM Ac-727
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