STRINGSTRING
ANS64567.1 ANS64567.1 ANS62250.1 ANS62250.1 ANS62264.1 ANS62264.1 ANS62462.1 ANS62462.1 ANS62727.1 ANS62727.1 ANS62800.1 ANS62800.1 ANS63059.1 ANS63059.1 ANS63146.1 ANS63146.1 ANS63190.1 ANS63190.1 xylB xylB mshC mshC dapA dapA ANS64466.1 ANS64466.1 thiG thiG ANS64925.1 ANS64925.1 ANS65068.1 ANS65068.1 glmS glmS ANS65949.1 ANS65949.1 ANS65968.1 ANS65968.1 ANS66002.1 ANS66002.1 mshD mshD purL purL rpsF rpsF purA purA rpsR-2 rpsR-2 ilvD ilvD rplC rplC rpsC rpsC rpmJ rpmJ glmS-2 glmS-2 guaB guaB ANS67536.1 ANS67536.1 ANS67572.1 ANS67572.1 mshB mshB ANS68104.1 ANS68104.1 gatC gatC leuB leuB dapA-2 dapA-2 katG katG ANS68585.1 ANS68585.1 ANS68642.1 ANS68642.1 ANS69407.1 ANS69407.1 ANS69550.1 ANS69550.1 egtA egtA ANS70174.1 ANS70174.1 ANS70297.1 ANS70297.1 ANS70701.1 ANS70701.1 ANS70706.1 ANS70706.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANS64567.1enoyl-CoA hydratase. (247 aa)
ANS62250.1Hypothetical protein. (262 aa)
ANS62264.1enoyl-CoA hydratase/isomerase. (322 aa)
ANS62462.1LmbE. (270 aa)
ANS62727.1Epoxide hydrolase. (401 aa)
ANS62800.1enoyl-CoA hydratase. (266 aa)
ANS63059.1Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (484 aa)
ANS63146.1Epoxide hydrolase. (390 aa)
ANS63190.1Ribose-5-phosphate isomerase. (151 aa)
xylBXylulose kinase. (481 aa)
mshCcysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (409 aa)
dapADihydrodipicolinate synthase 2; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (303 aa)
ANS64466.1Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
thiGThiazole biosynthesis protein thiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (264 aa)
ANS64925.1Epoxide hydrolase. (331 aa)
ANS65068.1enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
glmSL-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (605 aa)
ANS65949.1Epoxide hydrolase. (317 aa)
ANS65968.1enoyl-CoA hydratase. (266 aa)
ANS66002.1enoyl-CoA hydratase. (244 aa)
mshDAcetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. (308 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (752 aa)
rpsF30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (96 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa)
rpsR-230S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (79 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (617 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (214 aa)
rpsC30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (274 aa)
rpmJ50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (37 aa)
glmS-2Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (615 aa)
guaBInosine 5' monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa)
ANS67536.1enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa)
ANS67572.1Hypothetical protein. (286 aa)
mshBHypothetical protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. (290 aa)
ANS68104.1enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
gatCglutamyl-tRNA(Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (98 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (347 aa)
dapA-2Dihydrodipicolinate synthase 1; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa)
katGCatalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (740 aa)
ANS68585.1enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (275 aa)
ANS68642.1Enoyl CoA dehydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (274 aa)
ANS69407.1Enoyl coA hydratase. (249 aa)
ANS69550.1enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa)
egtAHypothetical protein; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. (450 aa)
ANS70174.1Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa)
ANS70297.1Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (356 aa)
ANS70701.1enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa)
ANS70706.1Putative hydrolase or acyltransferase of alpha/beta superfamily. (379 aa)
Your Current Organism:
Streptomyces lincolnensis
NCBI taxonomy Id: 1915
Other names: ATCC 25466, BCRC 11173, CBS 630.70, CBS 699.69, CCRC 11173, CCRC:11173, DSM 2013, DSM 40355, IFO 13054, ISP 5355, JCM 4287, JCM 4488, KCTC 9088, KCTC 9089, NBRC 13054, NCIMB 9413, NRRL 2936, NRRL-ISP 5355, S. lincolnensis, VKM Ac-727
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