(62 nodes) Butanoate metabolism network (Streptomyces lincolnensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANS62250.1	Hypothetical protein. (262 aa)
	ANS62264.1	enoyl-CoA hydratase/isomerase. (322 aa)
	ANS62797.1	acetyl-CoA acetyltransferase. (387 aa)
	ANS62800.1	enoyl-CoA hydratase. (266 aa)
	ANS62930.1	Putative 3-oxoacid CoA-transferase subunit A. (260 aa)
	ANS63115.1	Succinate-semialdehyde dehydrogenase, NADP-dependent; Belongs to the aldehyde dehydrogenase family. (479 aa)
	ANS63116.1	Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
	ANS63161.1	3-hydroxybutyrate dehydrogenase. (266 aa)
	ANS63240.1	Thiamine pyrophosphate protein central region; Belongs to the TPP enzyme family. (546 aa)
	ANS63589.1	Putative aldehyde dehydrogenase. (461 aa)
	ANS63635.1	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (495 aa)
	ANS63800.1	Putative acetoacetyl-CoA synthetase. (658 aa)
	ANS64015.1	3-hydroxybutyryl-CoA dehydrogenase. (277 aa)
	ANS64567.1	enoyl-CoA hydratase. (247 aa)
	ANS64568.1	Coenzyme A transferase. (273 aa)
	ANS64571.1	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
	ANS64898.1	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
	ANS65068.1	enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
	ANS65412.1	Acetolactate synthase; Belongs to the TPP enzyme family. (547 aa)
	ANS65421.1	hydroxymethylglutaryl-CoA lyase. (313 aa)
	ANS65466.1	Decarboxylase. (273 aa)
	ANS65729.1	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
	ANS66002.1	enoyl-CoA hydratase. (244 aa)
	ANS66536.1	3-hydroxybutyryl-CoA dehydrogenase. (505 aa)
	ANS66972.1	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (470 aa)
	ANS67207.1	2-oxoglutarate ferredoxin oxidoreductase subunit beta. (359 aa)
	ANS67208.1	Oxidoreductase. (642 aa)
	ANS67370.1	Succinic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (537 aa)
	ANS67462.1	Succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa)
	ANS67463.1	Succinate dehydrogenase flavoprotein subunit. (584 aa)
	ANS67464.1	Succinate dehydrogenase membrane subunit. (160 aa)
	ANS67465.1	Succinate dehydrogenase cytochrome b-556 subunit. (110 aa)
	ANS67710.1	Fumarate reductase iron-sulfur subunit. (258 aa)
	ANS67711.1	Succinate dehydrogenase flavoprotein subunit. (644 aa)
	ANS67997.1	3-hydroxyacyl-CoA dehydrogenase. (282 aa)
	ANS68012.1	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
	ANS68166.1	Acetolactate synthase 1 catalytic subunit. (618 aa)
	ANS68167.1	Acetolactate synthase 3 regulatory subunit. (174 aa)
	ANS68320.1	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
	ANS68642.1	Enoyl CoA dehydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (274 aa)
	ANS68643.1	crotonyl-CoA reductase. (453 aa)
	ANS68645.1	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
	ANS69040.1	Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (428 aa)
	ANS69096.1	Crotonyl CoA reductase. (447 aa)
	ANS69098.1	Oxidoreductase. (608 aa)
	ANS69236.1	TPP-requiring enzyme; Belongs to the TPP enzyme family. (560 aa)
	ANS69359.1	Succinyl CoA:3-oxoadipate CoA transferase beta subunit. (214 aa)
	ANS69360.1	3-oxoacid CoA-transferase subunit A. (251 aa)
	ANS69387.1	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
	ANS69388.1	Fatty acid oxidative multifunctional enzyme. (724 aa)
	ANS69510.1	Oxidoreductase, zinc-binding dehydrogenase family protein. (345 aa)
	ANS69550.1	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa)
	ANS69612.1	Cytochrome b subunit. (222 aa)
	ANS69614.1	Succinate dehydrogenase flavoprotein subunit. (649 aa)
	ANS69615.1	Succinate dehydrogenase/fumarate reductase iron-sulfur subunit. (249 aa)
	ANS69705.1	3-hydroxybutyryl-CoA dehydrogenase. (287 aa)
	ANS70126.1	Formate acetyltransferase. (752 aa)
	ANS70129.1	Alcohol dehydrogenase, class IV; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (888 aa)
	ANS70473.1	Succinate-semialdehyde dehydrogenase, NADP-dependent; Belongs to the aldehyde dehydrogenase family. (483 aa)
	ANS70600.1	crotonyl-CoA reductase. (480 aa)
	ANS70602.1	Hydroxybutyryl CoA reductase. (283 aa)
	ANS70701.1	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa)

Your Current Organism:

Streptomyces lincolnensis

NCBI taxonomy Id: 1915
Other names: ATCC 25466, BCRC 11173, CBS 630.70, CBS 699.69, CCRC 11173, CCRC:11173, DSM 2013, DSM 40355, IFO 13054, ISP 5355, JCM 4287, JCM 4488, KCTC 9088, KCTC 9089, NBRC 13054, NCIMB 9413, NRRL 2936, NRRL-ISP 5355, S. lincolnensis, VKM Ac-727

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANS62250.1	ANS62797.1	SLINC_0026	SLINC_0573	Hypothetical protein.	acetyl-CoA acetyltransferase.	0.594
ANS62250.1	ANS64015.1	SLINC_0026	SLINC_1791	Hypothetical protein.	3-hydroxybutyryl-CoA dehydrogenase.	0.734
ANS62250.1	ANS64571.1	SLINC_0026	SLINC_2347	Hypothetical protein.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.594
ANS62250.1	ANS64898.1	SLINC_0026	SLINC_2674	Hypothetical protein.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.594
ANS62250.1	ANS65421.1	SLINC_0026	SLINC_3197	Hypothetical protein.	hydroxymethylglutaryl-CoA lyase.	0.477
ANS62250.1	ANS65729.1	SLINC_0026	SLINC_3505	Hypothetical protein.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.594
ANS62250.1	ANS66536.1	SLINC_0026	SLINC_4312	Hypothetical protein.	3-hydroxybutyryl-CoA dehydrogenase.	0.734
ANS62250.1	ANS67997.1	SLINC_0026	SLINC_5773	Hypothetical protein.	3-hydroxyacyl-CoA dehydrogenase.	0.734
ANS62250.1	ANS68012.1	SLINC_0026	SLINC_5788	Hypothetical protein.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.594
ANS62250.1	ANS68643.1	SLINC_0026	SLINC_6419	Hypothetical protein.	crotonyl-CoA reductase.	0.684
ANS62250.1	ANS69096.1	SLINC_0026	SLINC_6872	Hypothetical protein.	Crotonyl CoA reductase.	0.684
ANS62250.1	ANS69098.1	SLINC_0026	SLINC_6874	Hypothetical protein.	Oxidoreductase.	0.734
ANS62250.1	ANS69387.1	SLINC_0026	SLINC_7163	Hypothetical protein.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.594
ANS62250.1	ANS69388.1	SLINC_0026	SLINC_7164	Hypothetical protein.	Fatty acid oxidative multifunctional enzyme.	0.926
ANS62250.1	ANS69705.1	SLINC_0026	SLINC_7481	Hypothetical protein.	3-hydroxybutyryl-CoA dehydrogenase.	0.734
ANS62250.1	ANS70600.1	SLINC_0026	SLINC_8376	Hypothetical protein.	crotonyl-CoA reductase.	0.684
ANS62250.1	ANS70602.1	SLINC_0026	SLINC_8378	Hypothetical protein.	Hydroxybutyryl CoA reductase.	0.734
ANS62264.1	ANS62797.1	SLINC_0040	SLINC_0573	enoyl-CoA hydratase/isomerase.	acetyl-CoA acetyltransferase.	0.594
ANS62264.1	ANS64015.1	SLINC_0040	SLINC_1791	enoyl-CoA hydratase/isomerase.	3-hydroxybutyryl-CoA dehydrogenase.	0.902
ANS62264.1	ANS64567.1	SLINC_0040	SLINC_2343	enoyl-CoA hydratase/isomerase.	enoyl-CoA hydratase.	0.620

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