(23 nodes) Alanine, aspartate and glutamate metabolism network (Synechococcus sp. SynAce01)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	carA	Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (384 aa)
	APD48640.1	Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
	APD48642.1	Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
	APD48722.1	Asparagine synthase (glutamine-hydrolyzing); Derived by automated computational analysis using gene prediction method: Protein Homology. (613 aa)
	APD49064.1	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
	purQ	Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (217 aa)
	purA	Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (437 aa)
	APD47319.1	Glutamine synthetase type III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (723 aa)
	APD47363.1	Asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
	carB	Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1116 aa)
	APD47504.1	Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
	APD47604.1	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (572 aa)
	APD47737.1	Type III glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (415 aa)
	APD47754.1	Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
	argG	Argininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (410 aa)
	purF	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (506 aa)
	argH	RNA-binding protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (490 aa)
	glmS	Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (641 aa)
	APD49452.1	Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family. (463 aa)
	pyrB	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (353 aa)
	APD49502.1	Aspartoacylase; Catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AspA/AstE family. Aspartoacylase subfamily. (315 aa)
	APD48550.1	Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. (379 aa)
	APD48570.1	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa)

Your Current Organism:

Synechococcus sp. SynAce01

NCBI taxonomy Id: 1916956
Other names: S. sp. SynAce01

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APD47319.1	APD47737.1	BM449_02125	BM449_05000	Glutamine synthetase type III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.	Type III glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.	0.560
APD47319.1	APD48640.1	BM449_02125	BM449_10860	Glutamine synthetase type III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.	Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.902
APD47319.1	APD48722.1	BM449_02125	BM449_11340	Glutamine synthetase type III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.	Asparagine synthase (glutamine-hydrolyzing); Derived by automated computational analysis using gene prediction method: Protein Homology.	0.790
APD47319.1	carA	BM449_02125	BM449_10610	Glutamine synthetase type III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.	Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family.	0.834
APD47319.1	carB	BM449_02125	BM449_02475	Glutamine synthetase type III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.	Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family.	0.832
APD47319.1	glmS	BM449_02125	BM449_07850	Glutamine synthetase type III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.	Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	0.820
APD47319.1	purF	BM449_02125	BM449_06675	Glutamine synthetase type III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.	0.830
APD47363.1	APD48722.1	BM449_02455	BM449_11340	Asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Asparagine synthase (glutamine-hydrolyzing); Derived by automated computational analysis using gene prediction method: Protein Homology.	0.820
APD47504.1	APD47604.1	BM449_03420	BM449_04130	Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.	0.837
APD47504.1	APD47737.1	BM449_03420	BM449_05000	Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type III glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.	0.418
APD47504.1	APD47754.1	BM449_03420	BM449_05115	Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.467
APD47504.1	APD48550.1	BM449_03420	BM449_10320	Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family.	0.411
APD47504.1	APD48640.1	BM449_03420	BM449_10860	Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.418
APD47504.1	APD48642.1	BM449_03420	BM449_10870	Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.468
APD47504.1	APD48722.1	BM449_03420	BM449_11340	Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Asparagine synthase (glutamine-hydrolyzing); Derived by automated computational analysis using gene prediction method: Protein Homology.	0.837
APD47504.1	APD49064.1	BM449_03420	BM449_13470	Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.763
APD47504.1	APD49452.1	BM449_03420	BM449_08160	Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family.	0.509
APD47504.1	argG	BM449_03420	BM449_06585	Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Argininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily.	0.865
APD47504.1	argH	BM449_03420	BM449_07595	Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	RNA-binding protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.438
APD47504.1	carB	BM449_03420	BM449_02475	Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family.	0.581