STRINGSTRING
glyA glyA APD48305.1 APD48305.1 ppc ppc APD48529.1 APD48529.1 gpmI gpmI acsA acsA APD48642.1 APD48642.1 APD48668.1 APD48668.1 APD48689.1 APD48689.1 APD48824.1 APD48824.1 APD48829.1 APD48829.1 APD48932.1 APD48932.1 APD48933.1 APD48933.1 APD49633.1 APD49633.1 comB comB APD47245.1 APD47245.1 APD47271.1 APD47271.1 APD47357.1 APD47357.1 APD49302.1 APD49302.1 APD47786.1 APD47786.1 APD49358.1 APD49358.1 eno eno ackA ackA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (429 aa)
APD48305.1Fe-S cluster containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (991 aa)
APD48529.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa)
gpmIPhosphoglycerate mutase (2,3-diphosphoglycerate-independent); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (523 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa)
APD48642.1Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
APD48668.1Fructose-bisphosphatase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 2 family. (334 aa)
APD48689.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
APD48824.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (817 aa)
APD48829.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (157 aa)
APD48932.1S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
APD48933.1S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (288 aa)
APD49633.1Histidine phosphatase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (454 aa)
comB2-phosphosulfolactate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ComB family. (257 aa)
APD47245.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
APD47271.1Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (357 aa)
APD47357.1Histidine phosphatase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
APD49302.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
APD47786.1Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (455 aa)
APD49358.1HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (375 aa)
Your Current Organism:
Synechococcus sp. SynAce01
NCBI taxonomy Id: 1916956
Other names: S. sp. SynAce01
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