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frdB frdB bioB bioB petA petA sdhB sdhB iscS iscS ilvD ilvD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
frdBOriginal (2000) note: Cj0410, frdB, probable fumarate reductase iron-sulfur protein, len: 723 aa; similar to FRDB_WOLSU fumarate reductase iron-sulfur protein (EC 1.3.99.1) (239 aa), fasta scores; opt: 1211 z-score: 1762.6 E(): 0, 68.4% identity in 237 aa overlap. 65.8% identity to HP0191. Contains PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature and Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains., score 41.20,E-value 1.1e-10; Updated (2006) note: Pfam domain PF00111 2Fe-2S iron-sulfur cluster binding domain was iden [...] (241 aa)
bioBPutative biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (278 aa)
petAPutative ubiquinol-cytochrome C reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (167 aa)
sdhBOriginal (2000) note: Cj0438, sdhB, possibleble succinate dehydrogenase iron-sulfur protein, len: 321 aa; similar to e.g. DHSB_MYCGR succinate dehydrogenase (ubiquinone) iron-sulfur protein (EC 1.3.5.1) (297 aa),fasta scores; opt: 352 z-score: 442.4 E(): 2.4e-17, 29.3% identity in 215 aa overlap. No Hp ortholog, but 28.1% identical to HP0191 fumarate reductase, iron-sulfur subunit (frdB). Contains PS00197 2Fe-2S ferredoxins,iron-sulfur binding region signature, PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature, and Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and [...] (321 aa)
iscSOriginal (2000) note: Cj0240c, probable aminotransferase (nifS protein homolog), len: 393 aa; similar to many e.g. NIFS_KLEPN nifS protein (397 aa),fasta scores; opt: 1067 z-score: 1533.6 E(): 0, 47.0% identity in 383 aa overlap. 62.8% identity to HP0220. Contains PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature, PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site, and Pfam match to entry PF00266 aminotran_5, Aminotransferases class-V,score 358.80, E-value 5.9e-104; Updated (2006) note: Characterised within Escherichia coli with acceptable identity scor [...] (393 aa)
ilvDDihydroxy-acid dehydratase; Original (2000) note: Cj0013, ilvD, probable dihydroxy-acid dehydratase, len: 558 aa; highly similar to e.g. ILVD_ECOLI dihydroxy-acid dehydratase (EC 4.2.1.9) (605 aa), fasta scores; opt: 1091 z-score: 2191.4 E(): 0,46.9% identity in 597 aa overlap. 32.0% identity to HP1100 (6-phosphogluconate dehydratase). Contains PS00886 and PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signatures 1 and 2, and Pfam match to entry PF00920 ILVD_EDD, Dehydratase family, score 784.10, E-value 5.5e-232; Updated (2006) note: Characterised within Escherichia coli w [...] (558 aa)
Your Current Organism:
Campylobacter jejuni NCTC 11168
NCBI taxonomy Id: 192222
Other names: C. jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819 = NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
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