STRINGSTRING
cdtA cdtA hipO hipO mapA mapA ceuE ceuE cdtC cdtC cdtB cdtB lpxA lpxA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdtACytolethal distending toxin A; CDTs are cytotoxins which induce cell distension, growth arrest in G2/M phase, nucleus swelling, and chromatin fragmentation in HeLa cells. (268 aa)
hipOHippurate hydrolase; Cleaves hippuric acid into benzoic acid and glycine. Belongs to the peptidase M20 family. (383 aa)
mapAPutative liproprotein; Original (2000) note: Cj1029c, mapA, probable lipoprotein, len: 214 aa; identical to TR:Q46122 (EMBL:X80135) C. jeuni species specific mapA gene (214 aa). No Hp match. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site; Updated (2006) note: Studied in Campylobacter jejuni. No specific characterisation has been carried out yet. Functional classification - Membranes, lipoproteins and porins; PMID:7790451. (214 aa)
ceuEOriginal (2000) note: Cj1355, ceuE, probable enterochelin uptake periplasmic binding protein, len: 330 aa; highly similar to TR:Q46006 (EMBL:X88849) Campylobacter coli ceuE (328 aa), fasta scores; opt: 1903 z-score: 2111.3 E(): 0, 90.6% identity in 330 aa overlap,and similar to e.g. FATB_VIBAN ferric anguibactin-binding protein precursor (322 aa), fasta scores; opt: 540 z-score: 605.4 E(): 2e-26, 30.1% identity in 279 aa overlap. No Hp match. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site; Updated [...] (330 aa)
cdtCOriginal (2000) note: Cj0077c, cdtC, cytolethal distending toxin, len: 189 aa, identical to TR:Q46102 (EMBL:U51121) cdtC (189 aa). No Hp match. Contains N-terminal signal sequence; Updated (2006) note: Pfam domain PF03499 Cytolethal distending toxin C identified within CDS. Product modified to more specific family member due to motif match. Characterised within Campylobacter jejuni, so putative not added to product function. Functional classification -Pathogenicity; PMID:10688204, PMID:8675309, PMID:11083762. (189 aa)
cdtBOriginal (2000) note: Cj0078c, cdtB, cytolethal distending toxin, len: 265 aa; identical toTR:Q46101 (EMBL:U51121) cdtB (265 aa) and similar to e.g. TR:Q47089 (EMBL:U03293) Escherichia coli cdtB (273 aa), fasta scores; opt: 946 z-score: 1533.6 E(): 0, 55.2% identity in 268 aa overlap. No Hp match. Contains N-terminal signal sequence; Updated (2006) note: Prosite domain PRO1388 CDTOXINB, Cytolethal distending toxin B signature identified within CDS. Product modified to more specific family member due to motif match. Characterised within Campylobacter jejuni, so putative not added to pro [...] (265 aa)
lpxAacyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (263 aa)
Your Current Organism:
Campylobacter jejuni NCTC 11168
NCBI taxonomy Id: 192222
Other names: C. jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819 = NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
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