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| | thiL | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (320 aa) |
| | AQA01098.1 | Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa) |
| | AQA01136.1 | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (763 aa) |
| | AQA01246.1 | Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (638 aa) |
| | AQA01358.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa) |
| | AQA01394.1 | Adenylyltransferase/sulfurtransferase MoeZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa) |
| | AQA01507.1 | Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa) |
| | prpE | Catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (623 aa) |
| | AQA06077.1 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (249 aa) |
| | AQA01564.1 | Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa) |
| | AQA01570.1 | Bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (373 aa) |
| | folD | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa) |
| | AQA01746.1 | Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa) |
| | AQA01914.1 | PIG-L family deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa) |
| | mtnP | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (258 aa) |
| | mshA | D-inositol-3-phosphate glycosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. (433 aa) |
| | prpE-2 | Catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (623 aa) |
| | AQA02278.1 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa) |
| | AQA02299.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa) |
| | mshD | Mycothiol synthase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. (300 aa) |
| | AQA02553.1 | Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa) |
| | acsA | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (653 aa) |
| | AQA02707.1 | Lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa) |
| | AQA02733.1 | Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa) |
| | egtE | Ergothioneine biosynthesis PLP-dependent enzyme EgtE; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. (373 aa) |
| | egtD | L-histidine N(alpha)-methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. (325 aa) |
| | egtC | Ergothioneine biosynthesis protein EgtC; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. (226 aa) |
| | egtB | iron(II)-dependent oxidoreductase EgtB; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. (429 aa) |
| | egtA | Ergothioneine biosynthesis glutamate--cysteine ligase EgtA; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. (422 aa) |
| | BVC93_10375 | Glutamate synthase large subunit; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (579 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa) |
| | AQA03034.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa) |
| | AQA03211.1 | Biotin-independent malonate decarboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa) |
| | AQA06409.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa) |
| | AQA06420.1 | Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa) |
| | cysC | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family. (619 aa) |
| | AQA03643.1 | Sulfate adenylyltransferase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa) |
| | AQA03644.1 | Sulfotransferase; Catalyzes the sulfuryl group transfer from 3'- phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S). (267 aa) |
| | AQA03771.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa) |
| | AQA03779.1 | acetoacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (646 aa) |
| | metZ | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (405 aa) |
| | AQA03830.1 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (698 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa) |
| | thiE | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (221 aa) |
| | AQA03835.1 | Glycine oxidase ThiO; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa) |
| | AQA03836.1 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (65 aa) |
| | thiG | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (255 aa) |
| | AQA06468.1 | Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa) |
| | AQA03963.1 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa) |
| | AQA03966.1 | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa) |
| | mshB | N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. (300 aa) |
| | AQA04169.1 | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa) |
| | cysD | Sulfate adenylyltransferase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa) |
| | cysC-2 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (616 aa) |
| | BVC93_19545 | Diaminopimelate decarboxylase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa) |
| | AQA04294.1 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa) |
| | AQA04295.1 | Molybdopterin synthase sulfur carrier subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa) |
| | cysM | Cysteine synthase B; Catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa) |
| | AQA04384.1 | Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (233 aa) |
| | AQA04583.1 | Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (312 aa) |
| | AQA04845.1 | 5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (313 aa) |
| | AQA04881.1 | Molybdopterin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (1293 aa) |
| | AQA06007.1 | Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa) |
| | mshC | cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (412 aa) |
| | BVC93_23785 | Carboxylate--amine ligase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1250 aa) |
| | AQA04971.1 | precorrin-3B synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa) |
| | AQA04973.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa) |
| | AQA06701.1 | Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa) |
| | AQA05420.1 | Thiaminase II; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. (229 aa) |
| | AQA05562.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa) |
| | bioB | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (335 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (226 aa) |
| | AQA05587.1 | 8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa) |
| | bioA | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (438 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (399 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (640 aa) |
| | AQA05974.1 | Sulfite reductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (533 aa) |
