(12 nodes) Pyruvate dehydrogenase complex network (Mycobacterium sp. MS1601)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AQA06101.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
	AQA01651.1	4-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
	AQA02027.1	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
	BVC93_07815	Hypothetical protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
	AQA06238.1	4-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
	AQA03442.1	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (757 aa)
	AQA03770.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
	kgd	Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. (1253 aa)
	AQA04653.1	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (779 aa)
	AQA04770.1	Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (929 aa)
	AQA04815.1	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
	AQA05131.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)

Your Current Organism:

Mycobacterium sp. MS1601

NCBI taxonomy Id: 1936029
Other names: M. sp. MS1601

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQA01651.1	AQA06101.1	BVC93_03505	BVC93_03410	4-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.547
AQA01651.1	AQA06238.1	BVC93_03505	BVC93_08540	4-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	4-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.942
AQA02027.1	AQA03442.1	BVC93_05820	BVC93_14650	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.901
AQA02027.1	AQA03770.1	BVC93_05820	BVC93_16555	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990
AQA02027.1	AQA04653.1	BVC93_05820	BVC93_22020	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.855
AQA02027.1	AQA04770.1	BVC93_05820	BVC93_22745	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.980
AQA02027.1	AQA04815.1	BVC93_05820	BVC93_23030	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
AQA02027.1	BVC93_07815	BVC93_05820	BVC93_07815	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.993
AQA02027.1	kgd	BVC93_05820	BVC93_18705	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AQA03442.1	AQA02027.1	BVC93_14650	BVC93_05820	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.901
AQA03442.1	AQA03770.1	BVC93_14650	BVC93_16555	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.919
AQA03442.1	AQA04770.1	BVC93_14650	BVC93_22745	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.841
AQA03442.1	AQA04815.1	BVC93_14650	BVC93_23030	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.919
AQA03442.1	BVC93_07815	BVC93_14650	BVC93_07815	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.940
AQA03442.1	kgd	BVC93_14650	BVC93_18705	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.951
AQA03770.1	AQA02027.1	BVC93_16555	BVC93_05820	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990
AQA03770.1	AQA03442.1	BVC93_16555	BVC93_14650	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.919
AQA03770.1	AQA04653.1	BVC93_16555	BVC93_22020	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.919
AQA03770.1	AQA04770.1	BVC93_16555	BVC93_22745	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.963
AQA03770.1	BVC93_07815	BVC93_16555	BVC93_07815	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.634