(16 nodes) ATP-grasp fold network (Mycobacterium sp. MS1601)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	AQA01362.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (695 aa)
	purK	5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (399 aa)
	AQA01475.1	acetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
	AQA01499.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1807 aa)
	AQA06188.1	acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (640 aa)
	sucC	succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa)
	purD	Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (422 aa)
	AQA06420.1	Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
	AQA06457.1	Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. (420 aa)
	purT	Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (400 aa)
	AQA04338.1	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (690 aa)
	AQA04380.1	acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (662 aa)
	carB	Orotidine-5'-phosphate decarboxylase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1113 aa)
	BVC93_30200	Asparagine synthase (glutamine-hydrolyzing); Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (593 aa)
	BVC93_30585	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1130 aa)
	ddl	D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (373 aa)

Your Current Organism:

Mycobacterium sp. MS1601

NCBI taxonomy Id: 1936029
Other names: M. sp. MS1601

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQA01362.1	AQA01499.1	BVC93_01725	BVC93_02555	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.624
AQA01362.1	sucC	BVC93_01725	BVC93_06580	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.704
AQA01475.1	AQA01499.1	BVC93_02395	BVC93_02555	acetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.948
AQA01475.1	AQA04380.1	BVC93_02395	BVC93_20335	acetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.896
AQA01475.1	AQA06188.1	BVC93_02395	BVC93_06445	acetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.901
AQA01475.1	AQA06420.1	BVC93_02395	BVC93_14755	acetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.937
AQA01475.1	BVC93_30585	BVC93_02395	BVC93_30585	acetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.818
AQA01475.1	carB	BVC93_02395	BVC93_28760	acetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Orotidine-5'-phosphate decarboxylase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family.	0.499
AQA01475.1	sucC	BVC93_02395	BVC93_06580	acetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.914
AQA01499.1	AQA01362.1	BVC93_02555	BVC93_01725	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.624
AQA01499.1	AQA01475.1	BVC93_02555	BVC93_02395	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.948
AQA01499.1	AQA04338.1	BVC93_02555	BVC93_20070	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.624
AQA01499.1	AQA04380.1	BVC93_02555	BVC93_20335	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.948
AQA01499.1	AQA06188.1	BVC93_02555	BVC93_06445	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.949
AQA01499.1	AQA06420.1	BVC93_02555	BVC93_14755	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.846
AQA01499.1	BVC93_30585	BVC93_02555	BVC93_30585	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.983
AQA01499.1	carB	BVC93_02555	BVC93_28760	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Orotidine-5'-phosphate decarboxylase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family.	0.643
AQA01499.1	sucC	BVC93_02555	BVC93_06580	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.875
AQA04338.1	AQA01499.1	BVC93_20070	BVC93_02555	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.624
AQA04338.1	sucC	BVC93_20070	BVC93_06580	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.830