(31 nodes) Fructose and mannose metabolism network (Mycobacterium sp. MS1601)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AQA06062.1	GDP-mannose pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
	pfkA	6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (343 aa)
	AQA01452.1	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
	AQA01453.1	TobH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
	AQA01454.1	Phosphomannomutase/phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
	AQA02865.1	Alpha-1,2-mannosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
	AQA03142.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)
	AQA03234.1	Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
	AQA03341.1	Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
	BVC93_14865	PTS lactose transporter subunit IIC; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (324 aa)
	AQA03793.1	Class II fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (344 aa)
	AQA03813.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
	AQA03984.1	Fructose-bisphosphatase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
	AQA04313.1	L-rhamnose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
	AQA04315.1	Rhamnulokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
	xylA	Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the xylose isomerase family. (407 aa)
	AQA04428.1	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
	AQA04450.1	Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
	AQA04754.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (391 aa)
	AQA04944.1	Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
	AQA05244.1	Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
	fbp	Fructose-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (357 aa)
	AQA05544.1	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
	AQA05604.1	L-threonine 3-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
	tpiA	Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
	AQA06084.1	Phosphomannomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
	AQA01594.1	Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
	AQA01979.1	Cation:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
	AQA06200.1	Mannitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
	AQA02197.1	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
	BVC93_07335	Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)

Your Current Organism:

Mycobacterium sp. MS1601

NCBI taxonomy Id: 1936029
Other names: M. sp. MS1601

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQA01452.1	AQA01453.1	BVC93_02260	BVC93_02265	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	TobH protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.989
AQA01452.1	AQA01454.1	BVC93_02260	BVC93_02270	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphomannomutase/phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.991
AQA01452.1	AQA02197.1	BVC93_02260	BVC93_06870	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.902
AQA01452.1	AQA02865.1	BVC93_02260	BVC93_10960	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alpha-1,2-mannosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.409
AQA01452.1	AQA03142.1	BVC93_02260	BVC93_12695	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.525
AQA01452.1	AQA03793.1	BVC93_02260	BVC93_16690	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Class II fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	0.493
AQA01452.1	AQA03984.1	BVC93_02260	BVC93_17835	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fructose-bisphosphatase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.882
AQA01452.1	AQA04944.1	BVC93_02260	BVC93_23885	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.409
AQA01452.1	AQA06062.1	BVC93_02260	BVC93_02305	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	GDP-mannose pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.745
AQA01452.1	AQA06084.1	BVC93_02260	BVC93_02870	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphomannomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.954
AQA01452.1	AQA06200.1	BVC93_02260	BVC93_06865	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Mannitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.827
AQA01452.1	BVC93_14865	BVC93_02260	BVC93_14865	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS lactose transporter subunit IIC; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.	0.861
AQA01452.1	fbp	BVC93_02260	BVC93_25965	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fructose-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family.	0.831
AQA01452.1	pfkA	BVC93_02260	BVC93_00155	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.	0.903
AQA01452.1	tpiA	BVC93_02260	BVC93_28510	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.	0.654
AQA01452.1	xylA	BVC93_02260	BVC93_20055	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the xylose isomerase family.	0.587
AQA01453.1	AQA01452.1	BVC93_02265	BVC93_02260	TobH protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.989
AQA01453.1	AQA01454.1	BVC93_02265	BVC93_02270	TobH protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphomannomutase/phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.977
AQA01453.1	AQA02197.1	BVC93_02265	BVC93_06870	TobH protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.632
AQA01453.1	AQA02865.1	BVC93_02265	BVC93_10960	TobH protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alpha-1,2-mannosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.673