STRINGSTRING
AQA03964.1 AQA03964.1 AQA01084.1 AQA01084.1 purU purU AQA01244.1 AQA01244.1 AQA01328.1 AQA01328.1 AQA01440.1 AQA01440.1 AQA06080.1 AQA06080.1 folD folD AQA01787.1 AQA01787.1 AQA02114.1 AQA02114.1 purH purH purN purN AQA02143.1 AQA02143.1 BVC93_06885 BVC93_06885 AQA02382.1 AQA02382.1 AQA02725.1 AQA02725.1 tgt tgt AQA03511.1 AQA03511.1 AQA03525.1 AQA03525.1 AQA03565.1 AQA03565.1 AQA03571.1 AQA03571.1 AQA03638.1 AQA03638.1 AQA03802.1 AQA03802.1 AQA06457.1 AQA06457.1 purT purT AQA03965.1 AQA03965.1 glyA glyA AQA04054.1 AQA04054.1 AQA04421.1 AQA04421.1 AQA04791.1 AQA04791.1 AQA04797.1 AQA04797.1 AQA04798.1 AQA04798.1 AQA04810.1 AQA04810.1 gcvT gcvT AQA04845.1 AQA04845.1 AQA04886.1 AQA04886.1 BVC93_23785 BVC93_23785 AQA04972.1 AQA04972.1 AQA06670.1 AQA06670.1 AQA05014.1 AQA05014.1 AQA06684.1 AQA06684.1 AQA06704.1 AQA06704.1 BVC93_25955 BVC93_25955 AQA05359.1 AQA05359.1 AQA05361.1 AQA05361.1 AQA05523.1 AQA05523.1 fmt fmt thyX thyX AQA05877.1 AQA05877.1 thyA thyA AQA05897.1 AQA05897.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AQA03964.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
AQA01084.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (304 aa)
AQA01244.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
AQA01328.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
AQA01440.1HNH endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
AQA06080.1Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (757 aa)
folDBifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa)
AQA01787.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
AQA02114.15-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (203 aa)
purHBifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (523 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (210 aa)
AQA02143.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (293 aa)
BVC93_06885ABC transporter substrate-binding protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
AQA02382.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (631 aa)
AQA02725.1RDD family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
tgttRNA guanosine(34) transglycosylase Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose t [...] (408 aa)
AQA03511.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
AQA03525.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
AQA03565.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa)
AQA03571.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
AQA03638.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
AQA03802.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
AQA06457.1Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. (420 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (400 aa)
AQA03965.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (485 aa)
AQA04054.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
AQA04421.1Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
AQA04791.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)
AQA04797.1Urea carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
AQA04798.1Urea carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
AQA04810.1RDD family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (369 aa)
AQA04845.15,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (313 aa)
AQA04886.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (622 aa)
BVC93_23785Carboxylate--amine ligase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1250 aa)
AQA04972.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (602 aa)
AQA06670.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
AQA05014.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
AQA06684.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
AQA06704.1Segregation/condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. (282 aa)
BVC93_25955NADH-quinone oxidoreductase subunit N; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
AQA05359.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (81 aa)
AQA05361.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)
AQA05523.1methionyl-tRNA formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (309 aa)
thyXThymidylate synthase (FAD); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (250 aa)
AQA05877.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (159 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (266 aa)
AQA05897.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)
Your Current Organism:
Mycobacterium sp. MS1601
NCBI taxonomy Id: 1936029
Other names: M. sp. MS1601
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