(6 nodes) Cell redox homeostasis network (Sphingomonas sp. LM7)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AQR75194.1	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
	AQR72422.1	Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (85 aa)
	AQR72626.1	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. (106 aa)
	AQR73804.1	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
	AQR75918.1	Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
	AQR75145.1	Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)

Your Current Organism:

Sphingomonas sp. LM7

NCBI taxonomy Id: 1938607
Other names: S. sp. LM7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQR72422.1	AQR73804.1	BXU08_00940	BXU08_09220	Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.543
AQR72422.1	AQR75145.1	BXU08_00940	BXU08_17100	Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.	Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.561
AQR72422.1	AQR75194.1	BXU08_00940	BXU08_17355	Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.543
AQR72626.1	AQR73804.1	BXU08_02145	BXU08_09220	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.472
AQR72626.1	AQR75145.1	BXU08_02145	BXU08_17100	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.	Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.568
AQR72626.1	AQR75194.1	BXU08_02145	BXU08_17355	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.472
AQR72626.1	AQR75918.1	BXU08_02145	BXU08_14455	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.	Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.412
AQR73804.1	AQR72422.1	BXU08_09220	BXU08_00940	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.	0.543
AQR73804.1	AQR72626.1	BXU08_09220	BXU08_02145	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.	0.472
AQR73804.1	AQR75194.1	BXU08_09220	BXU08_17355	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.989
AQR73804.1	AQR75918.1	BXU08_09220	BXU08_14455	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.449
AQR75145.1	AQR72422.1	BXU08_17100	BXU08_00940	Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.	0.561
AQR75145.1	AQR72626.1	BXU08_17100	BXU08_02145	Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.	0.568
AQR75145.1	AQR75918.1	BXU08_17100	BXU08_14455	Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.953
AQR75194.1	AQR72422.1	BXU08_17355	BXU08_00940	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.	0.543
AQR75194.1	AQR72626.1	BXU08_17355	BXU08_02145	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.	0.472
AQR75194.1	AQR73804.1	BXU08_17355	BXU08_09220	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.989
AQR75194.1	AQR75918.1	BXU08_17355	BXU08_14455	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.449
AQR75918.1	AQR72626.1	BXU08_14455	BXU08_02145	Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.	0.412
AQR75918.1	AQR73804.1	BXU08_14455	BXU08_09220	Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.449